125 results on '"Volz, A"'
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2. Echt-Zeit-Quantifizierung von p53-Protein-Isoformen im Hochdurchsatz-Verfahren mit einem neuem Exon-spezifischen Luciferase-Reportersystem
3. Exon-specific isoform expression reporter systems (EXSISERS) – A novel reporter to monitor differential p53 protein-isoform expression in response to tumor-specific treatments
4. HBs-directed T cell engager antibodies foster efficient recruitment of T cells and lead to strong reduction of HBV infection in livers of humanized mice
5. Infectivity of an ancient hepatitis B virus cloned after retrieval from archaeological human remains
6. Comparative analysis and distribution of distinct HBV particles and antigens in serum of patients and human liver chimeric mice according to density
7. IDH1 targeting as a potential treatment for intrahepatic cholangiocarcinoma (iCCA)
8. In vivo labeling of nascent viral HBV and HDV RNA for investigating viral replication and clearance kinetics
9. Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and cccDNA silencing in vivo without affecting posttranslational modifications of cccDNA-bound histones
10. Pre-clinical characterization of an HBsAg-specific monoclonal antibody preventing HBV spreading and reducing HBV, HDV and HBsAg in serum of humanized mice
11. Both interferon and siRNA treatments promote reappearance of SMC5/6 complex but have different impact on cccDNA
12. Efficacy of HDV mono-infection with genotype 1 and 3 in CRPISPR/Cas generated humanized NTCP mice compared to human liver chimeric mice
13. Interferon α treatment leads to reappearance of the Smc5/6 complex in HBV-infected humanized mice and to its renewed degradation upon viral rebound
14. Hepatitis B virus activates expression of the RIG-like receptor pathway in murine intrahepatic cells in humanized mice
15. Mutations in the basal core promoter of HBV lead to intracellular accumulation of viral nucleic acids in vivo
16. Hepatitis B virus-specific T cell receptors with high functional redirect T cells to eliminate HBV
17. T cells transiently expressing TCRs against HBV show antiviral activity in HBV/HDV co-infected humanized mice
18. Vorsorge statt Nachsorge - Strukturierte Früherkennung von Leberfibrose und Leberzirrhose durch Screening der Allgemeinbevölkerung mit Hilfe des SEAL Programmes
19. HDV-GT3 shows similar induction of innate immunity compared to HDV-GT1 in humanized mice despite its high infection efficiency and intrahepatic activity
20. HBV infection alters the transcriptional regulation of FXR-dependent microRNAs
21. Differential response of culture-derived HDV-1 and HDV-3 strains to peg-IFNα treatment in human liver chimeric mice despite strong ISG induction
22. Analysis of liver biopsies reveals a strong intrahepatic reduction of HDV and inflammatory markers after treatment with Myrcludex B in combination with Tenofovir in chronic HBV/HDV infected patients
23. Interferon α treatment leads to reappearance of the Smc5/6 complex in HBV-infected humanized mice and to its renewed degradation upon viral rebound
24. T cells transiently expressing TCRs against HBV show antiviral activity in HBV/HDV co-infected humanized mice
25. Hepatitis B virus-specific T cell receptors with high functional redirect T cells to eliminate HBV
26. Mutations in the basal core promoter of HBV lead to intracellular accumulation of viral nucleic acids in vivo
27. Hepatitis B virus activates expression of the RIG-like receptor pathway in murine intrahepatic cells in humanized mice
28. Efficacy of HDV mono-infection with genotype 1 and 3 in CRPISPR/Cas generated humanized NTCP mice compared to human liver chimeric mice
29. Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice
30. Wissensstand, Präventionsverhalten und Therapieadhärenz von Patienten mit chronischer Hepatitis B in einem großen tertiären Zentrum in Deutschland
31. HDV-GT3 shows similar induction of innate immunity compared to HDV-GT1 in humanized mice despite its high infection efficiency and intrahepatic activity
32. HBV infection alters the transcriptional regulation of FXR-dependent microRNAs
33. Inhibition des Wnt-Signalwegs durch Salinomycin resultiert in Apoptose von CD133+/-Tumorstammzellen des kolorektalen Karzinoms in vitro und verringertem Tumorwachstum in vivo
34. Human liver chimeric mice as a new model of Hepatitis E Virus infection and preclinical drug evaluation
35. Hepatitis Delta Virus can persist and propagate through human cell division both in vitro and in vivo
36. Proliferation of hepatitis B virus infected human hepatocytes in humanized mice treated with the entry inhibitor Myrcludex-B induces strong cccDNA reduction and maintenance of cccDNA-free hepatocytes
37. Hemoxygenase-1 and its downstream product Biliverdin suppress HCV replication and provides hepatoprotective effects in humanized uPA/SCID mice
38. The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor
39. Different antiviral effects induced by interferon or entecavir in HDV infected human-chimeric uPA/SCID mice determined by new intrahepatic qRT-PCR assay
40. Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice
41. Lack of HBeAg does not induce stronger enhancement of innate immunity genes in humanized mice
42. Zellteilung Hepatitis B Virus infizierter Hepatozyten führt zur schnellen Reduktion von cccDNA und viraler Replikation in humanisierten Mäusen
43. Alpha-Amylase/Trypsin Inhibitors, novel activators of innate immunity in ex-vivo tissue explants
44. Hämoxygenase-1 Induktion in chimären uPA/SCID Mäusen schützt humane Hepatozyten und hemmt die HCV Replikation
45. Eine Hepatitis-Delta-Koinfektion führt im Vergleich zu einer Hepatitis-B-Monoinfektion in humanisierten Mäusen zu einer verstärkten Antwort des angeborenen Immunsystems und zur ausgeprägteren Induktion humanspezifischer Zytokine
46. Das Hepatitis Delta Virus persistiert mehrere Wochen in vivo und bleibt auch nach Hepatitis B Virus Superinfektion infektiös
47. PRETREATMENT OF HUMANIZED uPA/SCID MICE WITH INTERFERON ALPHA STRONGLY INHIBITS THE ESTABLISHMENT OF HBV INFECTION
48. THE ENTRY INHIBITOR MYRCLUDEX-B EFFICIENTLY BLOCKS VIRAL SPREADING IN VIVO IN HUMAN LIVER CHIMERIC uPA/ SCID MICE PREVIOUSLY INFECTED WITH HEPATITIS B VIRUS
49. TREATMENT WITH PEGYLATED INTERFERON-ALPHA INDUCES SUSTAINED SUPPRESSION OF BOTH VIRUS REPLICATION AND ANTIGENEMIA IN HUMANIZED uPA/SCID MICE STABLY INFECTED WITH HBV
50. HDV LACKING HBV CAN INFECT HUMAN HEPATOCYTES IN THE LIVER OF CHIMERIC uPA/SCID MICE AND PERSIST FOR AT LEAST SIX WEEKS BEFORE BEING RESCUED BY SUPERINFECTION WITH HBV
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