1. Wound healing in sickle cell leg ulcers.
- Author
-
Leigh, Rebecca and Downie, Fiona
- Subjects
SICKLE cell anemia treatment ,WOUND healing ,RISK assessment ,ANKLE ,LEG ulcers ,MORPHINE ,CLINICAL trials ,ENZYME inhibitors ,HEMOGLOBINS ,DRUG administration ,TERTIARY care ,ZINC ,DISCHARGE planning ,QUALITY of life ,TISSUE viability ,HYDROXYUREA ,NITRITES ,COMPRESSION therapy ,COMPRESSION garments ,HYDROCOLLOID surgical dressings ,WOUND care ,BLOOD transfusion ,RELAXATION for health ,DISEASE risk factors - Abstract
The normal physiology of wound healing is impacted by sickle cell disease (SCD). With SCD, the red blood cells are misshapen due to an abnormality of haemoglobin S. Sickle cell leg ulcers usually occur around the ankle and have very poor healing rates, with a detrimental impact on quality of life, particularly as they usually develop in patients who are in their 20s (Marti-Carvajal et al, 2021). This article looks at some of the treatment options for SCD and whether these treatments have an impact, either positively or to the detriment of leg ulcer/wound healing. There are multiple physiological factors influencing the development of sickle cell leg ulcers, and their [ABSTRACT FROM AUTHOR]
- Published
- 2024