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3. The Influence of Age on the Outcomes of Traumatic Brain Injury: Findings from a Japanese Nationwide Survey (J-ASPECT Study-Traumatic Brain Injury)

Author

Takigami, Masayoshi, Kamiyama, Kenji, Houkin, Kiyohiro, Nishi, Shougo, Yoshimoto, Tetsuyuki, Kaneko, Sadao, Oka, Koji, Ooyama, Hiroshi, Kamada, Kyousuke, Makino, Kenichi, Tokumitsu, Naoki, Sako, Kazuhiro, Suzuki, Susumu, Suzuki, Nozomi, Izumi, Naoto, Nitta, Kazumi, Ootaki, Masahumi, Isobe, Masanori, Nishiya, Mikio, Yamazaki, Takaaki, Mabuchi, Syouji, Ogasawara, Kuniaki, Kubo, Naohiko, Shimizu, Yukihiko, Saito, Keiichi, Yamanome, Tatumi, Yoshino, Atsuo, Fujitsuka, Mitsuyuki, Takami, Masaaki, Ohtaka, Hirotoshi, Hirano, Teruyuki, Shiokawa, Yosiaki, Okada, Takaharu, Suzuki, Ichiro, Kohno, Michihiro, Haraoka, Jou, Arai, Yoshinori, Kawamura, Noriyoshi, Isoshima, Akira, Yasue, Masaharu, Takayoshi Kobayashi, Mitsuhiko Hokari, Kawai, Kensuke, Maehara, Taketoshi, Arai, Hajime, Noguchi, Makoto, Hoshino, Haruhiko, Hiyama, Hirofumi, Yoshida, Kensaku, Utsugi, Osamu, Takeda, Yasuaki, Tamaki, Kouichi, Karasudani, Hirohide, Urabe, Takao, Kobayashi, Shiro, Nakamura, Michio, Koguchi, Yorio, Ono, Junichi, Suda, Sumio, Hadeishi, Hiromu, Fukutake, Toshio, Wakui, Kenji, Tanno, Hirokazu, Ishige, Naoki, Ohasi, Takashi, Sakai, Hideki, Nishimura, Yasuaki, Watanabe, Takayuki, Matsumoto, Takashi, Koketsu, Naoki, Hirose, Yuichi, Doyu, Manabu, Hasegawa, Toshinori, Kuwayama, Naoto, Terao, Shinichi, Mizutani, Nobuhiko, Suzaki, Noriyuki, Okuda, Satoshi, Yasui, Keizo, Seki, Yukio, Hasegawa, Yasuhiro, Ikeda, Akira, Takeuchi, Youtarou, Ohara, Sigeki, Araki, Yoshio, Wakabayashi, Toshihiko, Tanaka, Hisashi, Yoshimoto, Junpei, Sugiura, Makoto, Koichiro, Ogura, Kobayashi, Nozomu, Yamada, Tomonori, Kato, Amami, Toshiho, Ohtsuki, Wakayama, Akatsuki, Takahashi, Jun, Kataoka, Hiroharu, Yoshimine, Toshiki, Nakajima, Yoshikazu, Gi, Hidehuku, Uranishi, Ryunosuke, Nakamura, Yusaku, Yamanaka, Kazunori, Ohmori, Kazumi, Matsumoto, Hiroyuki, Oiwa, Yoshitugu, Uemura, Yosihiko, Fujiwara, Hiroaki, Iwai, Yoshiyasu, Morikawa, Masashi, Tane, Kazuyuki, Hashikawa, Kazuo, Fujinaka, Toshiyuki, Yoneda, Shunichi, Yamashita, Kohsuke, Kitano, Masahiko, Tominaga, Shinsuke, Nakamura, Kazuhito, Kono, Katsuhiko, Ohata, Kenji, Taniguchi, Hirokatsu, Hazama, Takanori, Kuroiwa, Toshihiko, Tamura, Yoji, Maeno, Kazusige, Arai, Motohiro, Iwase, Masaaki, Hashimoto, Kenji, Yamada, Keisuke, Turuno, Takashi, Ichinose, Tsutomu, Kurokawa, Shinichiro, Matsuyama, Takeshi, Fujita, Toshiaki, Yuguchi, Takamichi, Teramoto, Yoshihumi, Kakita, Hiroto, Matsuo, Takayuki, Izumo, Tsuyoshi, Ryu, Nobutoshi, Naoki Kitagawa, Wataru Haraguchi, Kaminogo, Makio, Sakamoto, Seisaburo, Tokunaga, Yosiharu, Urasaki, Ei-Ichirou, Kuratsu, Junichi, Takada, Akira, Terasaki, Tadashi, Hisami Oosima, Isao Fuwa, Yamashiro, Shigeo, Hiromasa Tsuiki, Makoto Yoshikawa, Koga, Kazunari, Egami, Hiroshi, Kawamura, Tadao, Mitsuo, Kunihiko, Masaki Morisige, Takamitu Hikawa, Takeda, Yuu, Yamaguchi, Yutaka, Shunro Uchinokura, Shiro Miyata, Goya, Tomokazu, Takeshima, Hideo, Yatsushiro, Kazutaka, Ohta, Hajime, Nagadou, Tatsui, Hirahara, Kazuho, Obara, Souichi, Seto, Hiroshi, Moroki, Koiti, Arita, Kazunori, Ishiuchi, Shogo, Uchihara, Toshimitsu, Mekaru, Susumu, Nagamine, Tomoaki, Jin Momoji, Naoki Tomiyama, Atusi Kimoto, Kouzi Idomari, Kadekaru, Tsutomu, Syamoto, Hirosi, Sasaki, Osamu, Minagawa, Makoto, Takahashi, Hideaki, Hiroyuki Arai, Kiyoshi Onda, Takeuchi, Shigekazu, Abe, Hiroshi, Fukuda, Osamu, Kouno, Mitsuo, Tamura, Tetsuro, Michiya Kubo, Yukio Horie, Hondo, Hiroaki, Takada, Hisashi, Masuoka, Toru, Shirasaki, Naoki, Nitta, Hisashi, Yasuo Katsuki, Makoto Kimura, Hisato Minamide, Yutaka Hayashi, Munemoto, Shigeru, Ikeda, Kiyonobu, Yutaka Hayashi, Mitsutoshi Nakada, Sato, Syuji, Hatano, Taketo, Yamamura, Osamu, Kabuto, Masanori, Jyunya Hayashi, Takahiro Sakuma, Kinouchi, Hiroyuki, Koizumi, Hidehito, Imae, Syougo, Fujita, Manabu, Suga, Masakazu, Kanehisa Kohno, Shinji Iwata, Zenke, Kiichiro, Fujisawa, Mutsuo, Mizobuchi, Hikaru, Hayashi, Satoru, Morimoto, Masanori, Ueba, Tetsuya, Nishimura, Hiroyuki, Ikawa, Naoki, Matsumoto, Yuzo, Kannuki, Seiji, Kagawa, Masahiro, Hayashi, Naoki, Atsushi Shindo, Takashi Tamiya, Yoshino, Kimihiro, Masaoka, Tetsuya, Nakahara, Ichiro, Satoshi Suzuki, Akira Nakamizo, Okamoto, Yuji, Takahashi, Haruki, Iihara, Koji, Hirakawa, Katsuyuki, Nagata, Shinji, Ookura, Akio, Yoshiro Kaneko, Hidenori Yoshida, Nakane, Hiroshi, Inoue, Isao, Hitotsumatsu, Tsutomu, Kouichi Kuramoto, Terukazu Kuramoto, Hiromichi Ooishi, Yoshihisa Matumoto, Masani Nonaka, Tooru Inoue, Morioka, Motohiro, Shuji Sakata, Hiroshi Sugimori, Takashima, Hiroshi, Ishihara, Shin-Ichiro, Suzuyama, Kenji, Miyazono, Masayuki, Itaro Hattori, Masafumi Morimoto, Ozaki, Satoshi, Hirota, Nobuo, Yasuhiko Mochimatsu, Yasunori Takemoto, Takagi, Makoto, Kenji Nakayama, Isao Yamamoto, Hiroshi Tanaka, Yoshinori Uchida, Sakata, Katsumi, Nobutaka, Kawahara, Nomura, Motohiro, Ozawa, Hitoshi, Tsumura, Kotaro, Michiyuki Maruyama, Makoto Inaba, Mori, Tatsuro, Mori, Takahisa, Sugitani, Masato, Tanaka, Yuichiro, Yamada, Masaru, Matsumae, Mitsunori, Onitsuka, Keiichirou, Tatsuya Takahashi, Kosuke Miyahara, Endou, Sumio, Takahashi, Hidekazu, Kaidu, Hiroyuki, Chikashi Maruki, Akira Tsunoda, Fujimaki, Takamitsu, Ooigawa, Hidetoshi, Masatsugu Uchida, Masahiko Tanaka, Kouiti Katoh, Hiroshi Wanihuti, Hyodo, Akio, Asakura, Ken, Nakajima, Shigeyoshi, Kanzawa, Takao, Kurihara, Hideyuki, Ohmori, Sigehiro, Hiroshi Kusunoki, Mitsugi Yoshinao, Magarisawa, Satoshi, Okabe, Shinichi, Kujiraoka, Yuuji, Tsuruoka, Shin, Takeshita, Mikihiko, Akira Matsumura, Tetsuya Yamamoto, Uemura, Kazuya, Tabata, Hitoshi, Sonobe, Makoto, Ryoji Yoshida, Masashi Nakatsukasa, Shimoeda, Norifumi, Kunimine, Hideo, Ishihara, Masayuki, Murai, Nozomu, Murakami, Nobukuni, Kidooka, Minoru, Iwamoto, Yoshihiro, Tenjin, Hiroshi, Masahiko Takamasu, Kouji Shiga, Mori, Nobuhito, Kose, Shigeru, Kohmura, Eiji, Matsumoto, Keigo, Sakaki, Takayuki, Miyake, Hiroji, Mabuchi, Eiichiro, Yokota, Masayuki, Yosihiro Kuga, Hideyuki Ohnishi, Kimura, Mitsuru, Masaaki Saiki, Osamu Narumi, Nakajima, Norio, Asahi, Minoru, Koyama, Junji, Noda, Shinya, Iida, Junichi, Fujita, Toyohisa, Nakase, Hiroyuki, Toru Hoshida, Hidehiro Hirabayashi, Fujimoto, Takayoshi, Nakao, Naoyuki, Tanaka, Yoshiyuki, Ozaki, Fuminori, Nakamura, Yoshinari, Miki, Kazuhito, Watanabe, Takashi, Hasegawa, Seiko, Konno, Hiromu, Takemura, Atsuhito, Okubo, Atsuya, Saito, Hitoshi, Taizen Nakase, Tatsuya Ishikawa, Toshio Sasajima, Hiroaki Shimizu, Sasou, Masayuki, Watanabe, Yoichi, Kiyoshi Saito, Taku Sato, Masahiro Satoh, Satoshi Taira, Koizumi, Takayuki, Shoji Mashiyama, Yasuhiro Suzuki, Oikawa, Tomoyoshi, Sonoda, Yukihiko, Shinjiro Saito, Rei Kondo, Shinoda, Atsuo, Kamatsuka, Eiichiro, So, Keiten, Kinjo, Toshihiko, Kennji Itou, Tooru Sasaki, Hiroaki Shimizu, Hidenori Endo, Karibe, Hirosi, Takahashi, Kou, Nakajima, Masayuki, Watanabe, Kazuyoshi, Takayama, Motohiro, Komuro, Taro, Fumio Suzuki, Hisao Hirai, Suzuki, Hidenori, Murata, Hiroto, Miya, Fumitaka, Kanamaru, Kenji, Tamura, Akira, Harada, Kiyoshi, Fukazawa, Seiji, Takehara, Seiya, Watanabe, Yoshihiko, Nakayama, Teiji, Hiroshi Nagura, Haruhiko Sato, Chiharu Tanoi, Shinji Amano, Kuroda, Katsuhiro, Morooka, Satoru, Masashi Kitagawa, Takafumi Wataya, Koide, Kazuo, Tanigawara, Tetsuya, Iwama, Toru, Ito, Junki, Noda, Shinji, Kouno, Kazuyuki, Kitazawa, Kazuo, Toshiki Takemae, Yoshikazu Kusano, Hokama, Masanobu, Yoshihisa Nishiyama, Hiroki Sato, Seguchi, Tatsuya, Yoshihiko Inui, Sumio Kobayashi, Oohigashi, Youji, Muraoka, Shinsuke, Miyatake, Masaki, Nakagawa Shinichi, Kensuke Hayashida, Inoue, Atsushi, Sakai, Keiichi, Yamaguchi, Shuhei, Fusao Ikawa, Tatsuya Mizoue, Hideki Irie, Gen Ishida, Kagawa, Takato, Namba, Yoichiro, Nakashima, Hiroyuki, Koji Abe, Isao Date, Uno, Masaaki, Sen Yamagata, Masaki Chin, Soitiro Takao, Hidemiti Sasayama, Kouji Muneda, Hideyuki Yoshida, Watanebe, Akira, Katou, Syouichi, Hamada, Yasuhiro, Suzuki, Michiyasu, Nishizaki, Takafumi, Yamashita, Katsuhiro, Ryuji Nakamura, Takaharu Nakamura, Wakabayashi, Shinichi, Okazaki, Takahito, Kurisu, Kaoru, Matsumoto, Masayasu, Katsuzo Kiya, Atsushi Tominaga, Syuichi Oki, Masaaki Shibukawa, Nakahara, Toshinori, Okita, Shinji, Torii, Tuyosi, Kenjirou Fujiwara, Minoru Nakagawa, Syuuhei Nishimura, Takashi Matsuoka, Naoyuki Isobe, Osamu Hamasaki, Shinji Nagahiro, Junichiro Satomi, Agawa, Masahito, Oka, Hirofumi, Yoshimura, Kunikazu, Kato, Tsutomu, Satoshi Minoshima, Nobuaki Kobayasi, Mikuni, Nobuhiro, Tanikawa, Rokuya, Sasaki, Jyunkou, Otawara, Yasunari, Tominaga, Teiji, Sasaki, Tatsuya, Takemura, Sunao, Kawakami, Masahisa, Ihara, Satoshi, Shibata, Yasushi, Saegusa, Takashi, Iuchi, Toshihiko, Ito, Chiaki, Okuda, Osamu, Yoshida, Kazunari, Masateru Katayama, Sadao Suga, Akihiro, Oikawa, Miura, Naohisa, Ota, Takahiro, Kumabe, Toshihiro, Suzuki, Sachio, Kumagai, Takashi, Nishimaki, Keiichi, Hongo, Kazuhiro, Shigeta, Hiroaki, Hattori, Kazuyoshi, Uozumi, Yoichi, Nakahara, Norimoto, Hashimoto, Nobukazu, Shu Imai, Shinichi Shirakami, Okumura, Yoshinari, Kazuhiro Yokoyama, Ryo Tamaki, Miyamoto, Susumu, Yamamoto, Kazuo, Ichioka, Tsugumichi, Inoue, Tsuyoshi, Kinoshita, Manabu, Saitoh, Minoru, Aihara, Hideo, Miyake, Hajimu, Tukasa Nishiura, Kotaro Ogihara, Nishino, Shigeki, Miyoshi, Yasuyuki, Arisawa, Tadashi, Shoji Tsuchimoto, Shigeru Daido, Kinoshita, Kimihisa, Keisuke Migita, Kiyoshi Yuki, Akatsuka, Keiichi, Fujisawa, Hirosuke, Shono, Tadahisa, Tsugu, Hitoshi, Hayashi, Shuji, Toshio Matsushima, Tatsuya Abe, Nakashima, Susumu, Tuji, Takehisa, Kaga, Akihiko, Kanemaru, Reizou, Takasaki, Koji, Imamura, Junichi, Noha, Masahiro, Watanabe, Saburo, Sakai, Nobuyuki, Hiroaki Minami, Yasuhisa Yoshida, Okumura, Tomoyoshi, Nishimura, Shinjitsu, Numazawa, Shinichi, Masanori Tsutsumi, Kiyoshi Kazekawa, Fukuyama, Kouzou, Fujimoto, Yasuhiro, Yamagami, Keitaro, Kurogi, Ryota, Kurogi, Ai, Nishimura, Kunihiro, Onozuka, Daisuke, Ren, Nice, Kada, Akiko, Nishimura, Ataru, Arimura, Koichi, Ido, Keisuke, Mizoguchi, Masahiro, Sakamoto, Tetsuya, Kayama, Takamasa, and Hagihara, Akihito

Published
2019
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14. Intraoperative cerebrospinal fluid leak graded by Esposito grade is a predictor for diabetes insipidus after endoscopic endonasal pituitary adenoma resection

Author

Tanji, Masahiro, primary, Mineharu, Yohei, additional, Kikuchi, Masahiro, additional, Nakagawa, Takayuki, additional, Sakamoto, Tatsunori, additional, Yamashita, Masaru, additional, Matsunaga, Mami, additional, Kuwata, Fumihiko, additional, Kitada, Yuji, additional, Terada, Yukinori, additional, Arakawa, Yoshiki, additional, Yoshida, Kazumichi, additional, Kataoka, Hiroharu, additional, and Miyamoto, Susumu, additional

Published
2021
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19. The Influence of Age on the Outcomes of Traumatic Brain Injury: Findings from a Japanese Nationwide Survey (J-ASPECT Study-Traumatic Brain Injury)

Author

Yamagami, Keitaro, primary, Kurogi, Ryota, additional, Kurogi, Ai, additional, Nishimura, Kunihiro, additional, Onozuka, Daisuke, additional, Ren, Nice, additional, Kada, Akiko, additional, Nishimura, Ataru, additional, Arimura, Koichi, additional, Ido, Keisuke, additional, Mizoguchi, Masahiro, additional, Sakamoto, Tetsuya, additional, Kayama, Takamasa, additional, Suzuki, Michiyasu, additional, Arai, Hajime, additional, Hagihara, Akihito, additional, Iihara, Koji, additional, Takigami, Masayoshi, additional, Kamiyama, Kenji, additional, Houkin, Kiyohiro, additional, Nishi, Shougo, additional, Yoshimoto, Tetsuyuki, additional, Kaneko, Sadao, additional, Oka, Koji, additional, Ooyama, Hiroshi, additional, Kamada, Kyousuke, additional, Makino, Kenichi, additional, Tokumitsu, Naoki, additional, Sako, Kazuhiro, additional, Suzuki, Susumu, additional, Suzuki, Nozomi, additional, Izumi, Naoto, additional, Nitta, Kazumi, additional, Ootaki, Masahumi, additional, Isobe, Masanori, additional, Nishiya, Mikio, additional, Yamazaki, Takaaki, additional, Mabuchi, Syouji, additional, Ogasawara, Kuniaki, additional, Kubo, Naohiko, additional, Shimizu, Yukihiko, additional, Saito, Keiichi, additional, Yamanome, Tatumi, additional, Yoshino, Atsuo, additional, Fujitsuka, Mitsuyuki, additional, Takami, Masaaki, additional, Ohtaka, Hirotoshi, additional, Hirano, Teruyuki, additional, Shiokawa, Yosiaki, additional, Okada, Takaharu, additional, Suzuki, Ichiro, additional, Kohno, Michihiro, additional, Haraoka, Jou, additional, Arai, Yoshinori, additional, Kawamura, Noriyoshi, additional, Isoshima, Akira, additional, Yasue, Masaharu, additional, Takayoshi Kobayashi, Mitsuhiko Hokari, additional, Kawai, Kensuke, additional, Maehara, Taketoshi, additional, Noguchi, Makoto, additional, Hoshino, Haruhiko, additional, Hiyama, Hirofumi, additional, Yoshida, Kensaku, additional, Utsugi, Osamu, additional, Takeda, Yasuaki, additional, Tamaki, Kouichi, additional, Karasudani, Hirohide, additional, Urabe, Takao, additional, Kobayashi, Shiro, additional, Nakamura, Michio, additional, Koguchi, Yorio, additional, Ono, Junichi, additional, Suda, Sumio, additional, Hadeishi, Hiromu, additional, Fukutake, Toshio, additional, Wakui, Kenji, additional, Tanno, Hirokazu, additional, Ishige, Naoki, additional, Ohasi, Takashi, additional, Sakai, Hideki, additional, Nishimura, Yasuaki, additional, Watanabe, Takayuki, additional, Matsumoto, Takashi, additional, Koketsu, Naoki, additional, Hirose, Yuichi, additional, Doyu, Manabu, additional, Hasegawa, Toshinori, additional, Kuwayama, Naoto, additional, Terao, Shinichi, additional, Mizutani, Nobuhiko, additional, Suzaki, Noriyuki, additional, Okuda, Satoshi, additional, Yasui, Keizo, additional, Seki, Yukio, additional, Hasegawa, Yasuhiro, additional, Ikeda, Akira, additional, Takeuchi, Youtarou, additional, Ohara, Sigeki, additional, Araki, Yoshio, additional, Wakabayashi, Toshihiko, additional, Tanaka, Hisashi, additional, Yoshimoto, Junpei, additional, Sugiura, Makoto, additional, Koichiro, Ogura, additional, Kobayashi, Nozomu, additional, Yamada, Tomonori, additional, Kato, Amami, additional, Toshiho, Ohtsuki, additional, Wakayama, Akatsuki, additional, Takahashi, Jun, additional, Kataoka, Hiroharu, additional, Yoshimine, Toshiki, additional, Nakajima, Yoshikazu, additional, Gi, Hidehuku, additional, Uranishi, Ryunosuke, additional, Nakamura, Yusaku, additional, Yamanaka, Kazunori, additional, Ohmori, Kazumi, additional, Matsumoto, Hiroyuki, additional, Oiwa, Yoshitugu, additional, Uemura, Yosihiko, additional, Fujiwara, Hiroaki, additional, Iwai, Yoshiyasu, additional, Morikawa, Masashi, additional, Tane, Kazuyuki, additional, Hashikawa, Kazuo, additional, Fujinaka, Toshiyuki, additional, Yoneda, Shunichi, additional, Yamashita, Kohsuke, additional, Kitano, Masahiko, additional, Tominaga, Shinsuke, additional, Nakamura, Kazuhito, additional, Kono, Katsuhiko, additional, Ohata, Kenji, additional, Taniguchi, Hirokatsu, additional, Hazama, Takanori, additional, Kuroiwa, Toshihiko, additional, Tamura, Yoji, additional, Maeno, Kazusige, additional, Arai, Motohiro, additional, Iwase, Masaaki, additional, Hashimoto, Kenji, additional, Yamada, Keisuke, additional, Turuno, Takashi, additional, Ichinose, Tsutomu, additional, Kurokawa, Shinichiro, additional, Matsuyama, Takeshi, additional, Fujita, Toshiaki, additional, Yuguchi, Takamichi, additional, Teramoto, Yoshihumi, additional, Kakita, Hiroto, additional, Matsuo, Takayuki, additional, Izumo, Tsuyoshi, additional, Ryu, Nobutoshi, additional, Naoki Kitagawa, Wataru Haraguchi, additional, Kaminogo, Makio, additional, Sakamoto, Seisaburo, additional, Tokunaga, Yosiharu, additional, Urasaki, Ei-Ichirou, additional, Kuratsu, Junichi, additional, Takada, Akira, additional, Terasaki, Tadashi, additional, Hisami Oosima, Isao Fuwa, additional, Yamashiro, Shigeo, additional, Hiromasa Tsuiki, Makoto Yoshikawa, additional, Koga, Kazunari, additional, Egami, Hiroshi, additional, Kawamura, Tadao, additional, Mitsuo, Kunihiko, additional, Masaki Morisige, Takamitu Hikawa, additional, Takeda, Yuu, additional, Yamaguchi, Yutaka, additional, Shunro Uchinokura, Shiro Miyata, additional, Goya, Tomokazu, additional, Takeshima, Hideo, additional, Yatsushiro, Kazutaka, additional, Ohta, Hajime, additional, Nagadou, Tatsui, additional, Hirahara, Kazuho, additional, Obara, Souichi, additional, Seto, Hiroshi, additional, Moroki, Koiti, additional, Arita, Kazunori, additional, Ishiuchi, Shogo, additional, Uchihara, Toshimitsu, additional, Mekaru, Susumu, additional, Nagamine, Tomoaki, additional, Jin Momoji, Naoki Tomiyama, additional, Atusi Kimoto, Kouzi Idomari, additional, Kadekaru, Tsutomu, additional, Syamoto, Hirosi, additional, Sasaki, Osamu, additional, Minagawa, Makoto, additional, Takahashi, Hideaki, additional, Hiroyuki Arai, Kiyoshi Onda, additional, Takeuchi, Shigekazu, additional, Abe, Hiroshi, additional, Fukuda, Osamu, additional, Kouno, Mitsuo, additional, Tamura, Tetsuro, additional, Michiya Kubo, Yukio Horie, additional, Hondo, Hiroaki, additional, Takada, Hisashi, additional, Masuoka, Toru, additional, Shirasaki, Naoki, additional, Nitta, Hisashi, additional, Yasuo Katsuki, Makoto Kimura, additional, Hisato Minamide, Yutaka Hayashi, additional, Munemoto, Shigeru, additional, Ikeda, Kiyonobu, additional, Yutaka Hayashi, Mitsutoshi Nakada, additional, Sato, Syuji, additional, Hatano, Taketo, additional, Yamamura, Osamu, additional, Kabuto, Masanori, additional, Jyunya Hayashi, Takahiro Sakuma, additional, Kinouchi, Hiroyuki, additional, Koizumi, Hidehito, additional, Imae, Syougo, additional, Fujita, Manabu, additional, Suga, Masakazu, additional, Kanehisa Kohno, Shinji Iwata, additional, Zenke, Kiichiro, additional, Fujisawa, Mutsuo, additional, Mizobuchi, Hikaru, additional, Hayashi, Satoru, additional, Morimoto, Masanori, additional, Ueba, Tetsuya, additional, Nishimura, Hiroyuki, additional, Ikawa, Naoki, additional, Matsumoto, Yuzo, additional, Kannuki, Seiji, additional, Kagawa, Masahiro, additional, Hayashi, Naoki, additional, Atsushi Shindo, Takashi Tamiya, additional, Yoshino, Kimihiro, additional, Masaoka, Tetsuya, additional, Nakahara, Ichiro, additional, Satoshi Suzuki, Akira Nakamizo, additional, Okamoto, Yuji, additional, Takahashi, Haruki, additional, Hirakawa, Katsuyuki, additional, Nagata, Shinji, additional, Ookura, Akio, additional, Yoshiro Kaneko, Hidenori Yoshida, additional, Nakane, Hiroshi, additional, Inoue, Isao, additional, Hitotsumatsu, Tsutomu, additional, Kouichi Kuramoto, Terukazu Kuramoto, additional, Hiromichi Ooishi, Yoshihisa Matumoto, additional, Masani Nonaka, Tooru Inoue, additional, Morioka, Motohiro, additional, Shuji Sakata, Hiroshi Sugimori, additional, Takashima, Hiroshi, additional, Ishihara, Shin-Ichiro, additional, Suzuyama, Kenji, additional, Miyazono, Masayuki, additional, Itaro Hattori, Masafumi Morimoto, additional, Ozaki, Satoshi, additional, Hirota, Nobuo, additional, Yasuhiko Mochimatsu, Yasunori Takemoto, additional, Takagi, Makoto, additional, Kenji Nakayama, Isao Yamamoto, additional, Hiroshi Tanaka, Yoshinori Uchida, additional, Sakata, Katsumi, additional, Nobutaka, Kawahara, additional, Nomura, Motohiro, additional, Ozawa, Hitoshi, additional, Tsumura, Kotaro, additional, Michiyuki Maruyama, Makoto Inaba, additional, Mori, Tatsuro, additional, Mori, Takahisa, additional, Sugitani, Masato, additional, Tanaka, Yuichiro, additional, Yamada, Masaru, additional, Matsumae, Mitsunori, additional, Onitsuka, Keiichirou, additional, Tatsuya Takahashi, Kosuke Miyahara, additional, Endou, Sumio, additional, Takahashi, Hidekazu, additional, Kaidu, Hiroyuki, additional, Chikashi Maruki, Akira Tsunoda, additional, Fujimaki, Takamitsu, additional, Ooigawa, Hidetoshi, additional, Masatsugu Uchida, Masahiko Tanaka, additional, Kouiti Katoh, Hiroshi Wanihuti, additional, Hyodo, Akio, additional, Asakura, Ken, additional, Nakajima, Shigeyoshi, additional, Kanzawa, Takao, additional, Kurihara, Hideyuki, additional, Ohmori, Sigehiro, additional, Hiroshi Kusunoki, Mitsugi Yoshinao, additional, Magarisawa, Satoshi, additional, Okabe, Shinichi, additional, Kujiraoka, Yuuji, additional, Tsuruoka, Shin, additional, Takeshita, Mikihiko, additional, Akira Matsumura, Tetsuya Yamamoto, additional, Uemura, Kazuya, additional, Tabata, Hitoshi, additional, Sonobe, Makoto, additional, Ryoji Yoshida, Masashi Nakatsukasa, additional, Shimoeda, Norifumi, additional, Kunimine, Hideo, additional, Ishihara, Masayuki, additional, Murai, Nozomu, additional, Murakami, Nobukuni, additional, Kidooka, Minoru, additional, Iwamoto, Yoshihiro, additional, Tenjin, Hiroshi, additional, Masahiko Takamasu, Kouji Shiga, additional, Mori, Nobuhito, additional, Kose, Shigeru, additional, Kohmura, Eiji, additional, Matsumoto, Keigo, additional, Sakaki, Takayuki, additional, Miyake, Hiroji, additional, Mabuchi, Eiichiro, additional, Yokota, Masayuki, additional, Yosihiro Kuga, Hideyuki Ohnishi, additional, Kimura, Mitsuru, additional, Masaaki Saiki, Osamu Narumi, additional, Nakajima, Norio, additional, Asahi, Minoru, additional, Koyama, Junji, additional, Noda, Shinya, additional, Iida, Junichi, additional, Fujita, Toyohisa, additional, Nakase, Hiroyuki, additional, Toru Hoshida, Hidehiro Hirabayashi, additional, Fujimoto, Takayoshi, additional, Nakao, Naoyuki, additional, Tanaka, Yoshiyuki, additional, Ozaki, Fuminori, additional, Nakamura, Yoshinari, additional, Miki, Kazuhito, additional, Watanabe, Takashi, additional, Hasegawa, Seiko, additional, Konno, Hiromu, additional, Takemura, Atsuhito, additional, Okubo, Atsuya, additional, Saito, Hitoshi, additional, Taizen Nakase, Tatsuya Ishikawa, additional, Toshio Sasajima, Hiroaki Shimizu, additional, Sasou, Masayuki, additional, Watanabe, Yoichi, additional, Kiyoshi Saito, Taku Sato, additional, Masahiro Satoh, Satoshi Taira, additional, Koizumi, 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Kiyoshi Kazekawa, additional, Fukuyama, Kouzou, additional, and Fujimoto, Yasuhiro, additional

Published
2019
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32. Intraoperative Cerebrospinal Fluid Leak Graded by Esposito Grade Is a Predictor for Diabetes Insipidus After Endoscopic Endonasal Pituitary Adenoma Resection.

Author

Tanji, Masahiro, Mineharu, Yohei, Kikuchi, Masahiro, Nakagawa, Takayuki, Sakamoto, Tatsunori, Yamashita, Masaru, Matsunaga, Mami, Kuwata, Fumihiko, Kitada, Yuji, Terada, Yukinori, Arakawa, Yoshiki, Yoshida, Kazumichi, Kataoka, Hiroharu, and Miyamoto, Susumu

Subjects
*CEREBROSPINAL fluid leak, *DIABETES insipidus, *PITUITARY tumors, *PREOPERATIVE risk factors, *LOGISTIC regression analysis, *ENDOSCOPIC surgery
Abstract

Diabetes insipidus (DI) is a well-known complication of transsphenoidal surgery. However, the risk factors for DI remain controversial. We conducted a retrospective study of patients who underwent endoscopic transsphenoidal surgery for pituitary adenoma at our institution during a 5-year period. The patients were divided into a DI group and a non-DI group. Logistic regression analyses were used to identify risk factors for postoperative DI. In subgroup analysis, the DI group was divided into transient DI and permanent DI groups, and perioperative factors were compared between groups. Of 101 patients, 58 were in the non-DI group (57.4%) and 43 were in the DI group (42.6%). Permanent DI occurred in 7 patients (6.9%). In univariate analyses, statistically significant risk factors were suprasellar extension, tumor functionality, and intraoperative cerebrospinal fluid leaks by Esposito grade. In multivariate logistic regression analysis, Esposito grade was the only statistically significant risk factor (P = 0.015). The frequency of DI increased as the Esposito grade increased (P = 0.0002 for the trend). In subgroup analysis, postoperative nadir sodium concentration was lower in the permanent DI group (128.1 ± 2.78 mmol/L) than in the transient DI group (135 ± 1.22 mmol/L; P = 0.035), and the optimal cutoff value was 124.5 mmol/L, with a sensitivity of 57.1% and a specificity of 91.7% (area under the curve = 0.76, P = 0.034). Intraoperative cerebrospinal fluid leak by Esposito grade is associated with postoperative DI. These data can be applied to help identify high-risk patients who need more aggressive follow-up and fluid management. [ABSTRACT FROM AUTHOR]

Published
2022
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