5 results on '"Alex J. Vanni"'
Search Results
2. Transurethral reconstruction of fossa navicularis strictures with dorsal inlay buccal mucosa graft urethroplasty
- Author
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M Ryan, Farrell, Jack G, Campbell, Lawrence, Zhang, Samuel, Nowicki, and Alex J, Vanni
- Subjects
Male ,Urethral Stricture ,Treatment Outcome ,Urologic Surgical Procedures, Male ,Urethra ,Mouth Mucosa ,Humans ,Constriction, Pathologic ,Middle Aged ,Retrospective Studies - Abstract
To describe a single stage, glans-sparing urethroplasty technique for fossa navicularis strictures using a transurethral dorsal inlay buccal mucosa graft.We conducted a retrospective review of a prospectively maintained urethral stricture database to identify all fossa navicularis strictures reconstructed with a single stage, transurethral dorsal inlay buccal mucosa graft urethroplasty (5/2015-6/2020). Primary outcomes were anatomic success, defined as the ability to pass a 17 Fr flexible cystoscope, and functional success, defined as the lack of obstructive voiding symptoms and no need for further procedures. Secondary outcomes were postoperative complications and patient satisfaction.Sixteen patients were included. Mean age was 63.1 years (43.9-75.6) and mean stricture length was 1.7 cm (1.4-2.0). Stricture etiology included internal trauma (62.5%), idiopathic (25.0%), and lichen sclerosus (12.5%). Prior endoscopic procedures were done in 75% of patients. Over a median follow-up of 28.8 months (IQR 17.6-38.0), anatomic success was 15/16 (93.8%) and functional success was 16/16 (100%). The single anatomic recurrence was at 4.2 months postoperatively. No additional procedures were required. Urinary tract infection occurred in 25% (4/16). There were no instances of de novo erectile dysfunction, chordee, or wound infection. All patients would recommend urethroplasty to others and all patients were either very satisfied (83.3%) or satisfied (16.7%) with the procedure. Penile sensitivity was unchanged in 83.3%, increased in 8.3% and decreased in 8.3%.Transurethral dorsal inlay buccal mucosa graft urethroplasty is a viable option for reconstruction of fossa navicularis strictures that avoids splitting the glans and results in excellent cosmesis.
- Published
- 2021
3. Multicenter analysis of posterior urethroplasty complexity and outcomes following pelvic fracture urethral injury
- Author
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Rachel Moses, Niels V. Johnsen, Alex J. Vanni, Thomas G. Smith, Sean P. Elliott, Jill C. Buckley, Garrick M. Greear, Lee C. Zhao, Bryan B. Voelzke, Bradley A. Erickson, Jeremy B. Myers, Benjamin N. Breyer, Nejd F. Alsikafi, Nima Baradaran, and Michael A. Granieri
- Subjects
Urethral injury ,Nephrology ,Adult ,Male ,medicine.medical_specialty ,Urologic Surgical Procedures, Male ,Adolescent ,Urethral stricture ,Urology ,Urethroplasty ,medicine.medical_treatment ,030232 urology & nephrology ,Anastomosis ,Surgical failure ,03 medical and health sciences ,Fractures, Bone ,Young Adult ,0302 clinical medicine ,Urethra ,Internal medicine ,medicine ,Humans ,Pelvic Bones ,Retrospective Studies ,business.industry ,Perineal approach ,Middle Aged ,medicine.disease ,Surgery ,Treatment Outcome ,030220 oncology & carcinogenesis ,Pelvic fracture ,business - Abstract
To analyze outcomes of posterior urethroplasty following pelvic fracture urethral injuries (PFUI) and to determine risk factors for surgical complexity and success. Patients who underwent posterior urethroplasty following PFUI were identified in the Trauma and Urologic Reconstructive Network of Surgeons (TURNS) database. Demographics, injury patterns, management strategies, and prior interventions were evaluated. Risk factors for surgical failure and the impact of ancillary urethral lengthening maneuvers (corporal splitting, pubectomy and supracrural rerouting) were evaluated. Of the 436 posterior urethroplasties identified, 122 were following PFUI. 83 (68%) patients were acutely managed with suprapubic tubes, while 39 (32%) underwent early endoscopic realignment. 16 (13%) patients underwent pelvic artery embolization in the acute setting. 116 cases (95%) were completed via a perineal approach, while 6 (5%) were performed via an abdominoperineal approach. The need for one or more ancillary maneuvers to gain urethral length occurred in 4 (36%) patients. Of these, 44 (36%) received corporal splitting, 16 (13%) partial or complete pubectomy, and 2 (2%) supracrural rerouting. Younger patients, those with longer distraction defects, and those with a history of angioembolization were more likely to require ancillary maneuvers. 111 patients (91%) did not require repeat intervention during follow-up. Angioembolization (p = 0.03) and longer distraction defects (p = 0.01) were associated with failure. Posterior urethroplasty provides excellent success rates for patients following PFUI. Pelvic angioembolization and increased defect length are associated with increased surgical complexity and risk of failure. Surgeons should be prepared to implement ancillary maneuvers when indicated to achieve a tension-free anastomosis.
- Published
- 2019
4. Clinical significance of cystoscopic urethral stricture recurrence after anterior urethroplasty: a multi-institution analysis from Trauma and Urologic Reconstructive Network of Surgeons (TURNS)
- Author
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Rachel Moses, Alex J. Vanni, Sean P. Elliott, Jill C. Buckley, Thomas G. Smith, Jeremy B. Myers, Bradley A. Erickson, Nejd F. Alsikafi, Lee C. Zhao, Nima Baradaran, Thomas W. Gaither, Benjamin N. Breyer, Bryan B. Voelzke, Darshan P. Patel, and Kirkpatrick B. Fergus
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Adult ,Male ,medicine.medical_specialty ,Urologic Surgical Procedures, Male ,Urethral stricture ,Urology ,Urethroplasty ,medicine.medical_treatment ,Clinical Sciences ,030232 urology & nephrology ,03 medical and health sciences ,0302 clinical medicine ,Urethra ,Lower urinary tract symptoms ,Recurrence ,medicine ,Humans ,Clinical significance ,Treatment outcome ,Urethrostomy ,Retrospective Studies ,Urethral Stricture ,medicine.diagnostic_test ,business.industry ,Cystoscopy ,Urology & Nephrology ,Middle Aged ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Hypospadias ,030220 oncology & carcinogenesis ,business ,Self report - Abstract
PURPOSE:To assess the functional Queryoutcome of patients with cystoscopic recurrence of stricture post-urethroplasty and to evaluate the role of cystoscopy as initial screening tool to predict future failure. METHODS:Cases with cystoscopy data after anterior urethroplasty in a multi-institutional database were retrospectively studied. Based on cystoscopic evaluation, performed within 3-months post-urethroplasty, patients were categorized as small-caliber (SC) stricture recurrence: stricture unable to be passed by standard cystoscope, large-caliber (LC) stricture accommodating a cystoscope, and no recurrence. We assessed the cumulative probability of intervention and the quality of life scores in association with cystoscopic recurrence 1-year post-urethroplasty. Patients with history of hypospadias, perineal urethrostomy, urethral fistula, and meatal pathology were excluded. RESULTS:From a total of 2630 men in our cohort, 1054 patients met the inclusion criteria: normal (n = 740), LC recurrence (n = 178), and SC recurrence (n = 136) based on the first cystoscopic evaluation performed at median 111 days postoperatively. Median follow-up was 350 days (IQR 121-617) after urethroplasty. Cystoscopic recurrence was significantly associated with secondary interventions (2.7%, 6.2%, 33.8% in normal, LC, and SC groups, respectively). Quality of life variables were not statistically significantly different among the three study groups. CONCLUSIONS:Many patients with cystoscopic recurrence do not need an intervention after initial urethroplasty. Despite good negative predictive value, cystoscopy alone may be a poor screening test for stricture recurrence defined by patient symptoms and need for secondary interventions.
- Published
- 2018
5. Radiation-induced complex anterior urinary fistulation for prostate cancer: a retrospective multicenter study from the Trauma and Urologic Reconstruction Network of Surgeons (TURNS)
- Author
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Alex J. Vanni, Mohannad A. Awad, Christopher McClung, Thomas W. Gaither, Hadley Wyre, Benjamin N. Breyer, Sean P. Elliott, Jeremy B. Myers, Suprita Krishna, Bradley A. Erickson, Lee C. Zhao, E. Charles Osterberg, Scott C. Pate, and Joshua A. Broghammer
- Subjects
Male ,medicine.medical_specialty ,Urinary Fistula ,Urology ,medicine.medical_treatment ,Urinary system ,Fistula ,Urinary Bladder ,030232 urology & nephrology ,Pubic symphysis ,Urinary Diversion ,Cystectomy ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,Postoperative Complications ,Interquartile range ,medicine ,Humans ,Radiation Injuries ,Aged ,Retrospective Studies ,business.industry ,Prostatic Neoplasms ,medicine.disease ,United States ,Surgery ,medicine.anatomical_structure ,Outcome and Process Assessment, Health Care ,030220 oncology & carcinogenesis ,Complication ,business ,Organ Sparing Treatments - Abstract
To characterize anterior urinary fistulae following radiotherapy for prostate cancer. Over 10 years, 31 men were identified to have an anterior urinary fistula. A retrospective database was created to evaluate patient demographics, presentation, diagnostic procedures, operative interventions, outcomes, and complications. Comparisons between men who underwent cystectomy versus bladder-sparing surgeries were performed. At a median age of 73 (interquartile range (IQR) 68.5, 79) years, presenting symptoms included as follows: pubic pain (19/31, 61%), urine drainage via fistula (10/31, 32%), or a superficial wound infection (6/31, 19%). Recent instrumentation prior to diagnosis of anterior urinary fistula was reported by 18/31 (58%) at a median of 14.9 months (IQR 7.9, 103.8) after manipulation. Anterior fistula formation was either isolated to the pubic symphysis (19/31, 61%) or the thigh (12/31, 38%). Nineteen men underwent a cystectomy, whereas 12 men underwent a fistula repair. Excluding grades 1 and 2, 30- and 90-day postoperative complications were limited to four and two men, respectively, all of whom had a grade 3 complication. At 6-month follow-up, 26/31 (84%) men reported their pain had resolved. There was one fistula recurrence managed with subsequent cystectomy. Complex anterior urinary fistulae to the pubic symphysis and thigh are devastating yet treatable conditions. Universally, these men have a history of radiotherapy and repeated endoscopic interventions. Surgical intervention with either cystectomy or primary repair was highly successful.
- Published
- 2016
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