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Recent research from Italy has documented a rapid method for the purification of wild-type and V804M mutant rearranged during transfection (ret) catalytic domain. "RET is a transmembrane Tyr kinase and [...]

The follicular variant of papillary thyroid carcinoma (FVPTC) was associated with ras mutation. "Although FVPTC has been classified as a papillary cancer based on nuclear features, its follicular growth pattern [...]

A novel loss-of-function deletion in the sodium/iodide symporter (NIS) gene was found in thyroid adenoma. "The NIS actively transports iodide into thyrocytes. However, in thyroid carcinoma, down-regulated or mis-targeted NIS [...]

Cyclooxygenase-2 (COX-2) inhibitors could be used to reverse the chemoresistance phenotype in medullary thyroid carcinoma (MTC). According to recent research published in the Journal of Clinical Endocrinology and Metabolism, "MTC [...]

No correlation was found between BRAF mutations and papillary thyroid carcinomas (PTCs). According to recent research published in the journal Clinical Endocrinology, "Genetic alterations in 4 oncogenes, namely RAS point [...]

The detection of BRAF mutations predicts the progress of papillary thyroid carcinoma (PTC) and Hashimoto thyroiditis (HT). According to recent research from South Korea, "The purpose of the present study [...]

Interleukin-12B gene polymorphisms are not linked to autoimmune thyroid disease. "Interleukin (IL)-12 is a key factor in cell-mediated immunity that drives the development of Th1 cells and stimulates T lymphocytes [...]