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Background: Workplace inspections are applied to facilitate the adherence to the occupational health and safety regulations. The Iranian Ministry of Health introduced a new software system for tablets to inspect workplaces., Objectives: The aim of this study was to take measurements of the usability, mental workload, and mood of inspectors., Methods: Inspectors used both pen-and-paper and tablet methods to inspect the automotive industry in a mixed-method procedure. The NASA-TLX score, QUIS score, I-PANAS (SF) situation, inspection time, and number of errors were collected throughout the procedure. The differences were investigated using a paired sample and the Wilcoxon signed ranks test., Results: In terms of efficacy, using the tablet resulted in lower error rates, but it took longer to complete the inspection task (P < 0.001). Participants perceived a lower workload when inspecting with a tablet rather than the traditional method. (Mental Demand: p < 0.002, Performance: p < 0.009, Effort: p < 0.012, TLX: p < 0.002 based on various subcomponents of NASA-TLX). The newly introduced system's usability was insufficient., Conclusion: Although the use of tablets has improved safety inspections, ergonomic redesign of the system and consideration of a user-centered approach, as well as inspector training, can make the system more likely to succeed. more...