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A recent report discusses research conducted at Federal University Minas Gerais in Belo Horizonte, Brazil, on the identification and confirmation of psychotropic substances in alcoholic beverages. The study aimed to address the issue of criminal practices involving spiked drinks that make individuals vulnerable to sexual assault. The researchers developed a dual analytical methodology using surface-enhanced Raman spectroscopy (SERS) and paper spray mass spectrometry (PS-MS) to identify these substances in drinks. The results demonstrate the potential of this methodology to be implemented in forensic laboratories and used as a tool for harm reduction at parties and festivals. [Extracted from the article]

A recent study conducted at the State University of Campinas in Brazil examined the impact of a mobile app-guided pelvic floor muscle training (PFMT) program on urinary symptoms and quality of life in women with urinary incontinence. The study included 154 women with stress urinary incontinence who were randomly assigned to either the app group or the control (paper) group. Both groups showed significant improvements in urinary symptoms and quality of life, but the app group exhibited a more substantial reduction in overactive bladder symptoms and had greater improvements in quality of life. The study suggests that PFMT guided by a mobile app may be more effective than home-based guidance for improving urinary symptoms and quality of life in women with urinary incontinence. [Extracted from the article]

A study conducted by researchers at Sao Paulo State University (UNESP) in Brazil explores the potential of piperine-loaded nanoemulsions as a drug delivery system for breast cancer treatment. Piperine, an alkaloid of natural origin, has shown anti-cancer activity but has limited effectiveness due to its physicochemical characteristics. The researchers developed and characterized piperine-loaded nanoemulsions, which demonstrated sustained release and increased cytotoxicity against breast cancer cell lines. This study contributes to the understanding of nanosystems as a strategy to optimize drug delivery and enhance the cytotoxic properties of lipophilic drugs like piperine in breast cancer treatment. [Extracted from the article]

A report from Federal University in Pampulha, Brazil highlights the challenges and disparities in the systemic treatment of ovarian cancer. The research emphasizes that ovarian cancer is a global health problem, with the mortality-to-incidence ratio expected to increase, particularly in low- and middle-income countries. The study identifies various barriers to access and care, including limited awareness, lack of genetic and tumor testing, limited surgical expertise, delays in approving new therapies, and high treatment costs. The researchers call for collaboration and action to address these inequities and promote health equity in the management and treatment of ovarian cancer. [Extracted from the article]