Search

Your search keyword '"Vasilenko SK"' showing total 4 results
Start Over Author "Vasilenko SK" Journal voprosy virusologii
4 results on '"Vasilenko SK"'

1. [The characteristics of influenza A/H1N1 viruses related to A/PR/8/34 isolated in the Mongolian People's Republic].

Author

Iamnikova SS, Nimadava P, Petrov NA, Vasilenko SK, Iakhno MA, Semenova NP, and L'vov DK

Subjects
Antigens, Viral analysis, Base Sequence, Child, Child, Preschool, Epitopes analysis, Hemagglutination Inhibition Tests, Humans, Infant, Influenza A virus enzymology, Influenza A virus genetics, Influenza A virus isolation & purification, Influenza, Human microbiology, Molecular Sequence Data, Mongolia, Neuraminidase analysis, Neuraminidase genetics, Influenza A Virus, H1N1 Subtype, Influenza A virus immunology
Abstract

Investigations of the antigenic structure and genome of influenza A (H1N1) viruses isolated in the Mongolian People's Republic in 1982, 1983, 1986 and 1987 from children with acute respiratory diseases using monoclonal antibodies and nucleotide sequencing revealed 4 strains identical to the prototype strain A/PR/8/34 (H1N1), variant M. Sinai, and 8 strains closely similar to the epidemic strain A/USSR/90/77 (H1N1) in the antigenic structure and A/Leningrad/54 (H1N1) in the primary structure of HA.

Published
1991

2. [Primary structure of the hemagglutinin gene in strains of the influenza virus A/Leningrad/624/86 and A/Leningrad/621/86 serologic subtype H1N1].

Author

Petrov NA, Kozeletskaia KN, Vasilenko SK, Zhamsrangiĭn N, Grinbaum EB, Luzianina TIa, and Golubev DB

Subjects
Base Sequence, Influenza A virus classification, Molecular Sequence Data, RNA, Viral genetics, Serotyping, Genes, Viral genetics, Hemagglutinins, Viral genetics, Influenza A Virus, H1N1 Subtype, Influenza A virus genetics
Abstract

A molecular analysis was made of genomes of influenza A (H1N1) virus strains, the causative agents of an epidemic in Leningrad, 1986. The primary structure of hemagglutinin gene of two of these strains, A/Leningrad/624/86 and A/Leningrad/621/86, was established, as well as partial primary structure of PB1 gene of certain current strains of the A (H1N1) subtype. A hypothesis of a "shift" of PB1 gene in 1950-1957 is suggested.

Published
1990

3. [The primary structure of the hemagglutinin gene of strain A/Riga/9977/86--a drift variant of influenza virus A(H3N2)].

Author

Petrov NA, Vasilenko SK, Gorbunov IuA, Vtorushina IA, Grinbaum EB, Litvinova OM, Luzianina TIa, and Golubev DB

Subjects
Base Sequence, Molecular Sequence Data, Antigenic Variation genetics, Genes, Viral genetics, Hemagglutinins, Viral genetics, Influenza A Virus, H3N2 Subtype, Influenza A virus genetics
Abstract

The hemagglutinin gene primary structure of influenza virus A/Riga/9977/86 (H3N2) belonging to the "Coen/84" antigenic subgroup was determined by primer sequencing. A comparative analysis confirmed that the reversions of amino acids in the late stages of the H3 influenza virus subtype antigenic drift became more frequent and the antigenic variants remained in epidemic circulation longer. The possible role of some mutations is discussed.

Published
1990

4. [The characteristics of the hemagglutinin from persistent variants of the influenza virus A/Victoria/35/72 (H3N2)].

Author

Medvedeva MN, Petrov NA, Vasilenko SK, Simanovskaia VK, and Golubev DB

Subjects
Base Sequence, Electrophoresis, Polyacrylamide Gel, Genes, Viral genetics, Hemagglutinins, Viral analysis, Molecular Sequence Data, Mutation genetics, Time Factors, Virion genetics, Antigenic Variation genetics, Hemagglutinins, Viral genetics, Influenza A Virus, H3N2 Subtype, Influenza A virus genetics
Abstract

Electrophoresis in polyacrylamide gel of the reference influenza A/Victoria/35/72 (H3N2) virus and its persisting variants (PV) showed that the PV isolated on the 158th day from the moment of persistence modelling (PV158) had mutation in the gene of hemagglutinin (HA). This mutation is manifested by incomplete HA synthesis at 40 degrees C and increase of mobility of the light HA subunit (HA2). Analysis of nucleotide sequence of the greater part of HA gene of PV158 virus revealed 5 nucleotide substitutions four of which were significant. Three substitutions were found in Hal: 219 (Ser----Phe), 220 (Arg----Gly), 226 (Leu----Gln) and one in HA2: 156 (Thr----Asn). The importance of these mutations in the determination of the PV phenotype is discussed.

Published
1990

Catalog

Books, media, physical & digital resources
See catalog results