1. [Interaction of influenza A and B viruses with nanodiamond-based sorbents].
- Author
-
Ivanova VT, Ivanova MV, Burtseva EI, Garina EO, Trushakova SV, Shevchenko ES, Manykin AA, Isakova AA, Korzhenevskiĭ AP, and Spitsyn BV
- Subjects
- Adsorption, DNA, Viral isolation & purification, Humans, Influenza A virus isolation & purification, Influenza B virus isolation & purification, Influenza, Human prevention & control, Temperature, Time Factors, DNA, Viral chemistry, Influenza A virus chemistry, Influenza B virus chemistry, Influenza, Human virology, Nanodiamonds chemistry
- Abstract
The paper presents data on the sorption of influenza A(H1N1), A(H1N1)v, A(H3N2) viruses, cDNA of A(H1N1)v and B viruses on nanodiamonds and furnace charge. The sorption of viruses occurred in different solutions at 4-37 degrees C during 10-20 min. The rate of sorption varied with the concentration of a sorbent in the solution and its structure, but did not with the antigenic formula of viruses or temperature. The sorption capacity of furnace charge towards influenza A and B viruses was higher than that of nanodiamonds. Nonviral proteins (bovine serum albumin and influenza virus antibodies) were found to be bound by both sorbents. Viral desorption did not take place in physiological solution at 4 and 22 degrees C for 48 hours.
- Published
- 2012