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This paper was designed to report the results of comparative clinical and functional studies involving 89 patients who presented with moderately severe chronic obstructive pulmonary disease and were given the combined treatment with yellow turpentine bathtubs and bronchodilators inhalations with the use of a nebulizer. The patients comprising group 1 (n=29) were treated with yellow turpentine bathtubs and bronchodilators inhalations, those making up group 2 (n=30) received monotherapy with yellow turpentine bathtubs alone, and the patients included in group 3 (n=3) served as controls treated with the use of therapeutic physical exercises and symptomatic medications analogous to those given to the patients of the two former groups. The results of the study give evidence of the advantages of the rehabilitative complex including yellow turpentine bathtubs and atrovent inhalations over two alternative therapeutic modalities attributable to its pronounced anti-inflammatory and immune-corrective activity that resulted in the generalized improvement of bronchial patency, reduction of lung hypertension, and enhancement of physical tolerance; taken together, these effects ensured the best clinical results.

This paper summarizes the results of the application of thr magnetic fields for the treatment of experimental tumours, such as sarcoma M-1, alveolar liver cancer PC-1, and Erlich's carcinoma. The evidence of the anti-tumour action of both strong (1200 mTI) and weak (5 to 100 mTI) magnetic fields has been obtained. The author describes the modulating effect of the magnetic fields on the anti-tumour potency of photodynamic therapy and chemotherapy. The data concerning the impact of ferromagnetic hyperthermal therapy on the tumour growth and the survival rate among the tumour-bearing animals are presented.

Postoperative pain is a pressing medical problem, as it significantly reduces the quality of life of patients after surgical treatment. Chronic postoperative pain further disables patients and impairs their functional activity. Being a widespread interdisciplinary problem, postoperative pain requires the integration of various pain management methods in complex multimodal pain management in the acute period and treatment programs for its chronicity. The paper examines the possibilities of reflexology methods for the relief of acute and treatment of chronic postoperative pain. Integration of reflex effects from the first days after surgery makes it possible to more effectively and safely solve the problems of acute and chronic postoperative pain.

Background: Stability training, including rehabilitation, using the principle of biofeedback for support reaction on the stabilometric platform, is used to restore the functions of maintaining balance in medicine and to increase vertical stability in athletes, etc. in sports., Aim: To substantiate a procedure to correct the properties of human motor abilities during stability training, which are based on the consideration of the consistently involved levels of the nervous system in the construction of movements during games using biofeedback for support reaction., Material and Methods: The multilevel motion construction concept proposed by N.A. Bernstein (1947) was analyzed. Computer-assisted stabilometry, including Romberg's test with the eyes open and closed in the European standing (for 51 sec), was used for objective instrumental assessment of postural function. The study included 7 university students who belonged to a special medical group for their health status. The training was stopped when the student felt worse, tired, and unwilling to continue the game. The training duration was 12 to 22 minutes. To obtain reliable results, all stabilometric examinations were made from 8 to 9 o'clock in the morning. The study results were statistically analyzed using the goodness-of-fit test: Z-test (equality of the observed frequencies of two events), Wilcoxon signed rank test (when comparing dependent samples)., Results: The paper describes a relationship between the provisions of the multilevel motion construction concept proposed by N.A. Bernstein and the information about the levelled organization of movements during games via biofeedback for support reaction; guidelines for their use and experimental confirmation for the higher function of motor abilities: muscle synergy and kinesthetic sensitivity., Conclusion: There is evidence for the positive training effect on the function of motor ability properties of the pallidothalamic level of the nervous system during games via biological feedback for support reaction, their informative value compared with other stabilometric indicators.

Background: The paper presents the results of a study of the characteristics of the emotional sphere in patients with gastroesophageal reflux disease (GERD), using the original computer program developed by the author. In a number of studies, human psychoemotional characteristics were very significant in the occurrence of nausea, vomiting, and heartburn in patients with GERD. Psychogenic disorders of esophageal motility are widespread. However, until recently, the psychological characteristics of this category of patients, especially young ones, remain insufficiently studied., Aim: To study the emotional and personality characteristics of patients with GERD in order to improve its diagnosis and to determine the directions of psychocorrectional and rehabilitation work., Material and Methods: The study enrolled 68 patients with GERD and 68 clinically heathy volunteers. The computer program included the following scales: 1) the Scale of Conditions (Russian-language adaptation by A.B. Leonova, 1984); 2) the Scale of Differential Emotions (Russian-language adaptation by A.B. Leonova and M.S. Kapitsa, 2003); 3) the Chronic Fatigue Scale (modified b A.B. Leonova and I.V. Shishkina, 2003); and 4) the Spielberger State-Trait Anxiety Inventory. The Mann-Whitney U test was used to process empirical data., Results: The results of an analysis of experimental and psychological examinations were used to assess the emotional characteristics of patients with GERD. These patients were found to experience subjective discomfort and to frequently feel bad (p≤0.01). There were obviously relatively stable individual experiences of the anxiety-depressive complex in the profile of emotions. The patients were anxious and prone to fear and guilt (p≤0.01). Psychophysiologically, the patients with GERD had overt symptoms of physiological discomfort, including signs of sleep-wake cycle disorders, poorer health status, and obvious cognitive discomfort, as well as emotional and affective disorders, lower motivation, and social communication changes (p≤0.01). The patients with GERD were characterized by psychoemotional tension (p≤0.01) and anxiety that is sufficiently stable and prolonged, by transforming into a personality trait that becomes a factor of its change (p≤0.01)., Conclusion: The findings suggest that patients with GERD are characterized by a neurotic-like radical in the structure of personality and by a tendency to focus on their own somatic sensations and experiences. At the same time, the patients with GERD are commonly observed to have signs of obvious and severe chronic fatigue. There is more marked stress in the emotional sphere of these patients. Experimental and psychological examinations of the patient, by using this computer program, allow rehabilitation treatment and rehabilitation to be personified.

The paper reviews the literature on the efficiency of different rehabilitation methods after knee arthroplasty, such as continuous passive motion (CPM) therapy, exercises for balance and strengthening of hip muscles on the postoperative leg, and aquatic rehabilitation. It analyzes the optimal periods of rehabilitation initiation and continuance, studies of the Pilates system for patients after knee arthroplasty, kinesiotaping, fast-track rehabilitation, and Locomat robotic system. Various functional tests and questionnaire surveys are considered as performance measures. CPM therapy and the Pilates method are shown to require an additional investigation for inclusion in the standard rehabilitation program. Balance exercises have a positive impact on functional status and mobility in patients after surgery. Exercises for strengthening the hip muscles on the postoperative leg and aquatic training are recommended for use in routine practice. Kinesiotaping is successfully used to more effectively perform exercises, by reducing pain, edema and to improve a patient's psychological status. The Locomat can be used for walking technology training, which will be able to enhance the structure of a step and amortization function. The time taken in the rehabilitation center can be reduced using the fast-track rehabilitation program.

Aim: To study the impact of rehabilitation measures on the dynamics of pain syndrome and on the state of postural muscle balance in the early postoperative period in patients with degenerative-dystrophic diseases of the lumbar spine who have undergone decompressive-stabilizing interventions., Material and Methods: This paper comparatively analyzed the level of pain syndrome in the lumbar spine and lower extremities, the stabilometric indicators characterizing the amplitude of center-of-pressure oscillations in patients who had undergone decompressive-stabilizing operations at 7±2 days after surgical treatment for degenerative-dystrophic diseases of the lumbar spine. Two groups of 60 people in each were formed: rehabilitation measures were implemented, starting on day 2 of an early postoperative period (the duration of the latter was 7±2 days after surgery); the basic complex was supplemented with stabilometric training in Group 1 (a study group); only the basic complex was used in Group 2 (a comparison group)., Results: In the study group, the frequency of rehabilitation outcomes with an achieved excellent result depending on the level of pain syndrome in the lower extremities and spine on a visual analogue scale was 62.5 and 88.9%, respectively; which significantly statistically exceeds the proportion of patients with the same outcome in the comparison group (37.5 and 11.1%; p<0.01 in both cases). There was a statistically significant more pronounced decrease in the level of pain syndrome in the lumbar spine (p=0.0001) and lower limbs (p=0.003) in the patients of the study group in the early postoperative period. Intergroup comparison revealed a statistically significant decrease in all the indicators monitored in the study, which characterize the amplitude of the center-of-pressure oscillations. Moreover, the value of the oscillation area parameter between the patient groups differed by 1.76 and 1.83 times during Romberg's test with the eyes open or closed, respectively (p=0.0001)., Conclusion: The findings suggest that the comprehensive treatment supplemented with stabilometric training in the early postoperative period improves the state of postural muscle balance. There was a statistically significant predominance of compliance with normative values in patients of the study group during Romberg's test with the eyes open or closed (p=0.007 and p=0.00002, respectively), which contributes to a more marked decrease in the level of pain syndrome in the lumbar spine (p=0.001) and lower extremities (p=0.003).

Background: In recent decades, the volume of high-tech medical care in the field of orthopedics and traumatology, including endoprosthetic replacement of major joints (MJs) (the hip joint and/or the knee joint) in the lower extremities (LE) (LEMJ), has substantially increased. In this connection, there are an increasing number of patients in need of medical rehabilitation, to solve the problems of which needs the effective physical and rehabilitation medicine (PRM) techniques proven during researches to be introduced into practice., Objective: To analyze evidence-based studies containing sound data on the use of PRM technologies in the rehabilitation of patients after endoprosthetic replacement of LEMJs, to identify the most effective PRM technologies and to formulate recommendations for their use for practitioners, which are based on the evidence obtained during the analysis., Material and Methods: The paper is based on the scientometric analysis of 241 studies conducted in 2000 to 2018, which were devoted to the use of physical exercises and PRM technologies in the rehabilitation of patients after endoprosthetic replacement of LEMJs., Results: Over the past decade, there has been a tangible rise in the number of studies on endoprosthetic replacement of LEMJs. Some of the most studied PRM technologies having the proven effect are physical exercises in combination with neuromuscular electrical stimulation, kinesiotherapy, cryotherapy, and pressure therapy that is effective in preventing thromboembolism after surgery., Conclusion: The use of PRM technologies in the rehabilitation of patients after endoprosthetic replacement of LEMJs should be based on the results of high-quality randomized controlled clinical trials, which serve as the basis for the development of clinical recommendations. The process of analyzing the data of studies should be regular.

The paper presents the creative biography of Professor E.F. Levitsky, a famous Russian scientist, Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Director (1990-2009), Principal Researcher, Tomsk Research Institute of Balneology and Physiotherapy, Federal Biomedical Agency of Russia; Head, Department of Rehabilitation Medicine, Physiotherapy and Balneology, Faculty for Advanced Training and Professional Retraining of Specialists, Siberian State Medical University (Tomsk) (1995-2012). It reflects the main trends of scientific and social activities of the scientist.

Background: According to modern statistics, endometriosis is a disease that occupies the third place among the most problematic diseases of the female reproductive system, since it develops mainly in young women and, therefore, negatively affects their reproductive function. The paper presents the data obtained from a clinical trial of the combination treatment of Stages I-III endometriosis, including those using sanatorium-and-spa aftercare using radon tampons., Objective: To identify the most effective treatment for endometriosis., Material and Methods: Examinations were made in 348 women of reproductive age (mean age 30±4 years) with Stages I-III endometriosis. According to the therapy received, the patients were divided into 2 groups: 1) 174 patients who used drug therapy and radon tampons; 2) 174 patients who received only drug therapy., Results: Resultative positive changes were observed in Group 1 patients who received a combination of anti-inflammatory therapy, pathogenetic therapy of endometriosis, and sanatorium spa aftercare with radon tampons. The investigators excluded pain syndrome in 93.7% of cases, dysmenorrhea in 85.2%, and dyspareunia in 100%; menstrual blood loss decreased in 55.6% of patients; pregnancy occurred in 97.1% of women; the psychoemotional background improved in 100% of cases; in 96.2% of cases, subsequent recurrences were not observed (in the study period of 2014-2018)., Conclusion: The results of the study showed that a comprehensive and stage approach to treating Stages I-III endometriosis is fundamental to success in women's reproductive health.

The paper presents a review of the literature data reflecting the relevance and current views on the problem of facial feedback. It considers the relationship between the bioelectric activity of facial muscles and neuropsychic stress. The modern issues dedicated to the study of the correlation between the indicators assessing the tonic activity of facial muscles and psycho-emotional stress are highlighted. Particular emphasis is placed on the scientific concept of emotional proprioception, according to which facial muscle activity through the trigeminal and facial nerves affects the emotional centers of the brain, by improving or worsening the emotional state. The currently known methods for the correction of psychoemotional states, which are based on the feedback mechanism, are analyzed. The possibilities of using neuromuscular relaxation of the facial muscles to correct psychoemotional conditions are considered.

Background: To provide the population with inexpensive and effective medical products of domestic production is one of the most important public health tasks. These may include therapeutic muds, the high therapeutic value of which is confirmed by many years of positive experience with peloid therapy. The basis for interest in therapeutic muds is their efficiency in treating many diseases and regularly discovered new opportunities for their use., Objective: To strive to streamline the use of previously discovered therapeutic muds in Kazakhstan, to search for new hydromineral resources, and to register the latter as minerals., Material and Methods: The material was the results of the analysis of published data on studies of therapeutic muds, their use for medicinal purposes in sanatorium and extrasanatorium conditions, which had been prepared during the grant financing project 'Development of an innovative procedure for the qualitative and quantitative assessment of therapeutic muds in Southeastern Kazakhstan as hydromineral raw materials' (IRN AR 05130934) in 2018., Results and Conclusion: The paper provides a brief description of the results of the study of therapeutic mud deposits in Western Kazakhstan, North Kazakhstan, and the Almaty Region. It gives the main list of diseases in which the use of mud therapy is effective.

The survivors among the children and adolescents with a brain tumour are likely to show evidence of the impairment of the most important cognitive functions, such as attention, visual-motor integration, and working memory, following the completion of the antineoplastic treatment. The basic characteristics of these functions compromised in the patients presenting with the most serious cognitive deficiency are the information processing rate and the time needed for carrying out any cognitive activity in the patients experiencing deficit of white matter in the brain., Aim: The objective of the present study was to demonstrate the possibility and the effectiveness of the application of the new method for the stimulation of the information processing activity of the brain, the enhancement of its effectiveness, and the improvement of the quality of the visual-motor coordination in the children and adolescents following the completion of the antineoplastic treatment of brain tumours. This paper reports the first experience of the application of the Dynavision d2 visuo-motor reaction training device which has been used for the visual-motor integration and the increase of the information processing speed., Material and Methods: The sample included in the study was comprised of a total of 46 children at the mean age of 10.6±3.34 years that had undergone the treatment of the brain neoplasm. Each patient participated in 5 to 8 sessions of exercises with the use of the the Dynavision d2 visuo-motor reaction training device during 21 days., Results: All the treated patients exhibited the stable reduction of the mean time of the reaction from the first session to the last one. The comparison of the outcomes of the treatment between the children of different sexes has demonstrated better results (in absolute terms and in dynamics) in the girls in comparison with the boys. The exercises with the use of the Dynavision d2 visuo-motor reaction training device were not accompanied by any negative subjective sensations in the treated patients, nor did they induce the adverse somatic side effects., Conclusion: The results of the present study give evidence of both the applicability and the effectiveness of the application of the Dynavision d2 visuo-motor reaction training device for the diagnostics of the disturbances in the motor and visual coordination and the associated cognitive functions and for their correction in the children following the treatment of the neoplasm of the posterior cranial fossa.

This review presents the data on the receptor function of the skin and its role in the formation of the body's response to the action of physical therapy. Especially much attention is given in the paper to the influence of ultrasound, microwaves, laser radiation, various medical environments, and other physical factors on the morphofunctional condition of the skin receptors. Possible mechanisms of changes in receptor activity under effects of physical therapeutic factors are analyzed. Moreover, the paper summarizes the directions of further possible studies on the interactions between physical factors and cutaneous receptors.

This paper was designed to discuss the problems of co-morbidity and approaches to the rehabilitation of the patients presenting with gastroesophageal reflux disease and a concomitant pathology and to analyze the issues concerning the possible vertebro-visceral correlations inherent in the diseases of the internal organs., Aim: To evaluate the vertebro-neurological status of the thoracic segment of the vertebral column in the patients suffering from gastroesophageal reflux disease and to further improve the methods for their treatment taking into consideration the concomitant pathology, if any., Material and Methods: A total of 290 patients at the age varying from 25 to 60 (mean 44,3±11,3) years with the non-erosive form of gastroesophageal reflux disease were examined in the phase of its exacerbation. They included 132 (45.5%) men and 158 (54.5%) women. The duration of the disease averaged 13.1±3.3 years and that of the exacerbation period 1.2±0.5 months. All the patients underwent the vertebro-neurological examination. The visual analog scale was used to obtain the subjective characteristics of the pain syndrome associated with thoracalgia The quality of life of the patients was estimated based on the Medical Outcomes Study Short Form-36 (scores of MOS SF-36). To evaluate the effectiveness of the proposed approach to the treatment of the gastroesophageal reflux disease, the 260 participants of the study were randomly allocated to two groups, the main and control ones. The latter group was comprised of 130 patients given the standard treatment including the use of histamine H2-receptor antagonists, proton pump inhibitors, stimulators of the motility of the gastrointestinal tract, alginates, and other drugs, as indicated. The former group consisted of the remaining 130 patients undergoing the standard course of pharmacopuncture to correct the functional disorders in the thoracic segment of the vertebral column. The medications of choice for the purpose were the anti-homotoxic agents, such as placental compositum, co-enzyme compositum, and ubichinon compositum (Biologische Heilmittel Heel GmbH, Germany). The statistical analysis was performed with the use of the non-parametric methods based on the Statistica application software package ('StatSoft Inc.', США)., Results: The present article reports the results of the study that demonstrate significant strong positive correlation between the clinical manifestations of gastroesophageal reflux disease (the frequency and severity of symptoms) and thoracalgia and provides a rationale for the assessment of the vertebro-neurological status of the thoracic spine in the patients exhibiting the clinical signs of gastroesophageal reflux disease. The study substantiated the inclusion of pharmacopuncture with placenta compositum, co-enzyme compositum, and ubichinon compositum anti-homotoxic medications in the complex rehabilitation programs for the patients presenting with the clinical signs of gastroesophageal reflux disease and the concomitant thoracalgia symptoms. To assess the effectiveness of the proposed method for the treatment of this condition, such diagnostic criteria as the vertebro-neurological symptoms, coefficient of the thoracalgia-associated pain syndrome, the frequency and intensity of the gastroesophageal reflux disease symptoms, and the quality of life parameters were used., Conclusion: The results of the present study provide strong evidence that pharmacopuncture helps to improve the quality of life of the patients, alleviate thoracalgia symptoms and clinical signs of gastroesophageal reflux disease, and reduce the intensity of the pain syndrome caused by thoracalgia.

This paper is devoted to the characteristic of the informative value of the functional step test with the application of the heel cushions in the children for the purpose of differential diagnostics of anatomic and functional differences in the length of the lower extremities. A total of 85 schoolchildren with different length of the lower extremities have been examined. The comparative evaluation of the results of clinical and instrumental examinations was undertaken. The data obtained with the help of the functional step test give evidence of its very high sensitivity, specificity, and clinical significant as a tool for the examination of the children with different length of the low extremities. It is concluded that the test is one of the most informative predictors of the effectiveness of rehabilitation in the children with different length of the lower extremities.

This paper was designed to report the results of the application of two therapeutic modalities for the rehabilitation of 44 patients presenting with post-stroke locomotor disorders in the form of spastic hemiparesis. The patients allocated to the main group were treated with the use of the new kinesiotherapeutic methods including cryomassage and the Armeo robotic complex. The patients of the control group had to perform traditional therapeutic physical exercises in combination with classical massage and remedial gymnastics. It is concluded that the application of the combination of the modern kinesiotherapeutic factors exerting the positive corrective influence on different aspects of the locomotor deficiency in the upper extremities and the psychoemotional status of the patients has advantages over traditional physical exercise therapy in terms of clinical efficiency because it enhances the rehabilitative potential for these patients with serious locomotor problems.

This paper was designed to describe the main characteristics of general magnetic therapy and the mechanisms underlying its biological and therapeutic action. Special attention is given to the extensive application of this method in the routine clinical practice. The publications in the current scientific literature are reviewed in order to evaluate the potential of general magnetic therapy as a component of the combined treatment of various somatic pathologies, rehabilitation of the patients after surgical intervention with special reference to the management of the patients presenting with the oncological problems. The data suggesting good tolerability and high therapeutic effectiveness of the physiotherapeutic method under consideration.

This scientific review highlights peculiarities of the delivery of laser radiation to the tissues of the athlete's body by means of laser electrophoresis of biologically active substances and the possibilities for electrolaser myostimulation. The main features of electrical myostimulation based on the application of laser-generated radiation are described. The authors emphasize the necessity of taking into account the neurophysiological dependence of active and passive contractile muscular activity during training. They provide the scientifically grounded rationale for the combined use of coherent laser radiation and electrical stimulation. The list of scientific papers that confirm the effectiveness of the method being considered is presented. The authors compare this method with other techniques for the induced ion transfer. The beneficial influence of laserphoresis of succinic and hyaluronic acids on the athlete's body is reported with special reference to alleviating the pain syndrome. A number of phyto-extracts used for the purpose of laser electrophoresis are characterized. The authors demonstrate the application of the optional versions of this technique in various sports during the training and competition periods.

This paper presents the results of the systemic approach to the protection of health and prophylaxis of disability in the workers of industrial enterprises. The leading role in the technologies of rehabilitation (both short-term and long-term one) is played by the natural and physical therapeutic factors. The priority in the implementation of the therapeutic and health-promoting measures is given to the treatment based on the spa and health resort facilities as well as the factory health centers.

Unlabelled: This paper reports the results of the clinical observations and special investigations carried out with the involvement of the children presenting with acute respiratory diseases treated with the use of a Myramistin solution for inhalation., Material and Methods: The study included a total of 60 children with the above condition at the age varying between 2 and 17 years. Forty patients inhaled the Myramistin solution through a face mask connected to the nebulizer. The remaining 20 children that comprised the control group inhaled Myramistin in the form of a spray., Results: The study has demonstrated the effectiveness of the proposed method that produced beneficial effect on the clinical symptoms of the respiratory diseases and characteristics of peripheral blood. Moreover, it accelerated the recovery of the patients due to the anti-inflammatory and trophic action of the inhaled solution and promoted normalization of mucociliary clearance. The therapeutic effectiveness of the Myramistin spray was significantly lower than that of the solution., Conclusion: The results of the study provided a basis for the development of the optimal technologies for the application of the Myramistin inhalation solution to the treatment of the children presenting with acute respiratory diseases of the upper and lower parts of the respiratory tract.