1. [Photodynamic therapy in treatment of chorioid neovascularization].
- Author
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Avetisov SE, Budzinskaia MV, Kiseleva TN, Kazarian EE, Gurova IV, Loshchenov VB, Shevchik SA, Kuz'min SG, and Vorozhtsov GN
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Choroidal Neovascularization pathology, Fluorescein Angiography, Follow-Up Studies, Fundus Oculi, Humans, Indoles administration & dosage, Injections, Intravenous, Middle Aged, Organometallic Compounds administration & dosage, Radiation-Sensitizing Agents administration & dosage, Tomography, Optical Coherence, Treatment Outcome, Choroidal Neovascularization drug therapy, Indoles therapeutic use, Organometallic Compounds therapeutic use, Photochemotherapy methods, Radiation-Sensitizing Agents therapeutic use
- Abstract
The authors studied the effectiveness of photodynamic therapy (PDT) with Photosence, a Russian photosensitizer, in treatment of chorioid neovascularization (CNV) in cases of age-related macular degeneration (ARMD) and pathological myopia (PM). The subjects were 73 patients with CNV suffering from ARMD and PM. The efficiency of PDT and complex conservative therapy was compared using vision acuity measurement, retinal morphometry, and fluorescent eye ground angiography (FEGA), performed before treatment, immediately after treatment, and 1, 3, 6, and 12 months later. The study showed that PDT in patients with CNV, ARMD and PM was more efficient than pharmacotherapy. Vision acuity improved or stabilized, and the parameters of retinal morphometry and FEGA improved as well. The results of the study evidence high efficiency of PDT with Photosence in treatment of CNV with ARMD and PM.
- Published
- 2007