1. [Use of dibunol and delagil in the treatment of acute pancreatitis].
- Author
-
Buianov VM, Stupin IV, Zheltikov AN, and Sherstnev MP
- Subjects
- Acute Disease, Administration, Oral, Animals, Antioxidants pharmacology, Chloroquine administration & dosage, Chloroquine pharmacology, Dogs, Female, Humans, Infusions, Intravenous, Injections, Intramuscular, Lipid Peroxidation drug effects, Middle Aged, Pancreatitis metabolism, Phospholipases antagonists & inhibitors, Postoperative Care, Rats, Antioxidants administration & dosage, Butylated Hydroxytoluene administration & dosage, Chloroquine analogs & derivatives, Pancreatitis surgery
- Abstract
The effect of Dibunol and Delagil on the course of experimental pancreatitis was studied in experiments in 80 rats and 36 dogs. The intravenous injection of the drugs was shown to decrease lethality of the animals. Control of biochemical parameters has revealed decreased activity of amylase, lipase, trypsin and malonic dialdehyde, normalized level of superlight luminescence of blood plasma. A good medical effect was obtained in 15 patients with acute pancreatitis.
- Published
- 1988