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Extracorporeal methods of hemosorption and detoxication were used in treatment of 293 patients with purulent surgical infection of soft tissues complicated by sepsis. In 35 patients with the same nosology the methods in question were not employed. An analysis of the clinical observations has shown that lethality in the main group was reduced to 23.6%. The sorption technologies were shown to be most effective for normalization of leukocytosis, lekocytic index of intoxication, middle mass molecules in this group of patients.

Investigations of the lymphatic bed of lower extremities by the method of rentgen-contrast lymphography were performed in 64 patients with trophic ulcers of lower extremities and postthrombotic disease. The data obtained by lymphography allowed formation of a group of patients perspective for treatment by lymphotropic antibacterial therapy. The lymphotropic therapy using Gentamycin and Cefazolin resulted in a more rapid arresting of local inflammatory alterations and development of reparative processes in the trophic ulcer area and in normalization of the main clinico-laboratory parameters.

The results of using recombinant interleukin-2 from yeast for the treatment of patients with the sepsis syndrome are discussed. It is noted that there was a marked immunomodulating effect, the amount of endogenous interleukin-2 increased. The patients' state was shown to become less severe (according to the SAPS criterion), the patients felt better. A conclusion is made of the possibility in principle and expediency of using cytokines for the treatment of patients with the sepsis syndrome.

An original method of endolymphatic therapy with the stimulation of the lymph outflow was developed and used in 108 patients with peritonitis. The dynamics of intoxication parameters was studied during the endolymphatic therapy, indirect electrochemical oxidation of blood, photochemotherapy and traditional treatment. The method proposed has been found to be most efficient. The method of endolymphatic therapy with the lymph stimulation allowed lethality from peritonitis to be decreased to 7.4%.

The skin electric resistance in the representative points was measured by the Nakatani technique in 86 surgical patients during resuscitation. Two most informative indices were established: the average electric resistance of the skin and the renal index. A significant correlation (r = 0.78) was obtained between the average electric resistance of the skin and score sum SAPS. Changes of the renal index allow the dynamics of the patient's state to be estimated, and along with the electric resistance of the skin--the degree of traumatic consequences of the operative intervention. The method is simple and not dangerous for the patients.

Based on the experience with the treatment of 144 patients the authors recommend to use transfusions of autologous blood subjected to UV irradiation in the complex treatment of lymphostasis of lower extremities.

The work presents results of treatment of 1019 patients aged from 20 to 89 with postinjectional phlegmons. Operations were made on 1003 patients. Main causes of the appearance of the disease, choice of anesthesia and modern methods of treatment are discussed. The application of drugs of a composite effect in addition to early operation, the ultrasonic treatment of the purulent cavity, vacuum drainage followed by early secondary sutures make the terms of treatment of patients with postinjectional phlegmons shorter.