1. Production of experimental atrial septal defects
- Author
-
Noel L. Mills, Thomas E. Brodie, Terry D. King, and Sandra L. Thompson
- Subjects
medicine.medical_specialty ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Atrial septal defects ,Heart Septal Defects, Atrial ,03 medical and health sciences ,0302 clinical medicine ,Dogs ,Postoperative Complications ,Internal medicine ,mental disorders ,medicine ,Heart Septum ,Methods ,Animals ,cardiovascular diseases ,030212 general & internal medicine ,Heart Atria ,Cardiac catheterization ,Punch Biopsy ,Wound Healing ,business.industry ,Surgical Instruments ,Surgery ,Disease Models, Animal ,Cardiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Atrial septal defects (ASDs) were successfully created by punch biopsy technique in 67 dogs. The technique is simple, effective and provides an ideal model for the study of ASDs, either for testing closure devices or physiological experiments. The position and size of the defects may be varied according to preference. Of 45 animals subjected to cardiac catheterization, 39 (87 percent) has a patent atrial septal defect.
- Published
- 1976