1. Meningococcal pneumonia
- Author
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Matthias Vossen, Dieter Mitteregger, and Christoph Steininger
- Subjects
0301 basic medicine ,General Veterinary ,General Immunology and Microbiology ,Incidence ,030106 microbiology ,Public Health, Environmental and Occupational Health ,Neisseria meningitidis ,Meningococcal Infections ,03 medical and health sciences ,0302 clinical medicine ,Infectious Diseases ,Risk Factors ,Pneumonia, Bacterial ,Humans ,Molecular Medicine ,030212 general & internal medicine - Abstract
Neisseria meningitidis remains the most important cause of bacterial meningitis worldwide, particularly in children and young adults. The second most common and a potentially severe end-organ manifestation of invasive meningococcal disease (excluding systemic sepsis) is meningococcal pneumonia. It occurs in between 5% and 15% of all patients with invasive meningococcal disease and is thus the second most common non-systemic end-organ manifestation. To establish the diagnosis requires a high level of clinical awareness - the incidence is therefore very likely underreported and underestimated. This review of 344 meningococcal pneumonia cases reported in the Americas, Europe, Australia, and Asia between 1906 and 2015 presents risk factors, pathogenesis, clinical manifestations, diagnostic approaches, treatment, and prognosis of meningococcal pneumonia.
- Published
- 2016
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