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Objective Common carotid artery intima-media thickness (CIMT) is a non-invasively assessed marker of subclinical atherosclerosis. Our aim in this study was to investigate CIMT in women with gestational diabetes mellitus (GDM). Methods Thirty women with GDM and 40 unaffected women (as a control group) were included in the study. Blood samples were drawn from each woman in the morning after they had fasted for at least 8 h, and levels of fasting glucose, insulin, homocysteine, total cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, low-density lipo protein (LDL) cholesterol and very low-density lipo protein (VLDL) cholesterol were measured, along with the CIMT in the two groups. Results The mean triglyceride (P = 0.016) and VLDL cholesterol (P = 0.011) levels in the GDM group were significantly higher than those in the unaffected women. There were no significant differences between the groups with respect to plasma levels of total cholesterol, HDL cholesterol, LDL cholesterol and insulin. The mean homocysteine (P = 0.027) and fasting glucose (P = 0.019) levels in women with GDM were significantly higher than those in the control group. Patients with GDM had significantly higher CIMT than did the unaffected women (0.582 ± 0.066 mm vs. 0.543 ± 0.049 mm, P = 0.006). CIMT correlated positively with maternal age (r = 0.316, P = 0.008), body mass index (BMI) at the time of a 50-g oral glucose load test (r = 0.414, P = 0.001) and homocysteine levels (r = 0.332, P = 0.008), and fasting glucose (r = 0.265, P = 0.03 1) and 1-h glucose value (r = 0.410, P = 0.001) at the time of the oral glucose tolerance test. There was a positive correlation between the presence of GDM and CIMT (r = 0.372, P = 0.001). However, stepwise multiple regression analysis showed that GDM/no GDM (95% CI + 0.012 to + 0.076, P = 0.008) and BMI at the time of the 50-g test (95% CI + 0.001 to + 0.009, P = 0.011) were independent parameters related to CIMT. Conclusion Women with GDM have increased CIMT compared with unaffected women. [ABSTRACT FROM AUTHOR]

An abstract of the conference paper "Glucose challenge test between 130-140 mg/dl; adding abdominal circumference measurement difference between 29-33 weeks may predict macrosomia," by E. Tarim and colleagues is presented.

An abstract of the conference paper "Limb body wall defect: three different presentations with abdominal wall defects," by S. Hacivelioglu and colleagues is presented.

An abstract of the conference paper "First trimester maternal serum PAPP-A levels and macrosomia," by E. Tarim and colleagues is presented.