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Your search keyword '"Krispin, E."' showing total 20 results
Start Over Author "Krispin, E." Journal ultrasound in obstetrics & gynecology
20 results on '"Krispin, E."'

1. Consensus protocol for management of early and late twin–twin transfusion syndrome: Delphi study

Author

Krispin, E., primary, Javinani, A., additional, Odibo, A., additional, Carreras, E., additional, Emery, S. P., additional, Sepulveda Gonzalez, G., additional, Habli, M., additional, Hecher, K., additional, Ishii, K., additional, Miller, J., additional, Papanna, R., additional, Johnson, A., additional, Khalil, A., additional, Kilby, M. D., additional, Lewi, L., additional, Bennasar Sans, M., additional, Otaño, L., additional, Zaretsky, M. V., additional, Sananes, N., additional, Turan, O. M., additional, Slaghekke, F., additional, Stirnemann, J., additional, Van Mieghem, T., additional, Welsh, A. W., additional, Yoav, Y., additional, Chmait, R., additional, and Shamshirsaz, A. A., additional

Published
2024
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4. Implication of chromosomal microarray analysis prior to in‐utero repair of fetuses with open neural tube defects

Author

Zemet, R., primary, Krispin, E., additional, Johnson, R. M., additional, Kumar, N. R., additional, Westerfield, L. E., additional, Stover, S., additional, Mann, D. G., additional, Castillo, J., additional, Castillo, H. A., additional, Nassr, A. A., additional, Cortes, M. Sanz, additional, Donepudi, R., additional, Espinoza, J., additional, Whitehead, W. E., additional, Belfort, M. A., additional, Shamshirsaz, A. A., additional, and Van den Veyver, I. B., additional

Published
2023
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6. Perinatal outcomes of fetoscopic laser surgery for twin–twin transfusion syndrome in triplet pregnancy: cohort study, systematic review and meta‐analysis

Author

Mustafa, H. J., primary, Javinani, A., additional, Krispin, E., additional, Tadbiri, H., additional, Shamshirsaz, A. A., additional, Espinoza, J., additional, Nassr, A. A., additional, Donepudi, R., additional, Belfort, M. A., additional, Sanz Cortes, M., additional, Harman, C., additional, and Turan, O. M., additional

Published
2022
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7. Implication of chromosomal microarray analysis prior to in‐utero repair of fetal open neural tube defect.

Author

Zemet, R., Krispin, E., Johnson, R. M., Kumar, N. R., Westerfield, L. E., Stover, S., Mann, D. G., Castillo, J., Castillo, H. A., Nassr, A. A., Sanz Cortes, M., Donepudi, R., Espinoza, J., Whitehead, W. E., Belfort, M. A., Shamshirsaz, A. A., and Van den Veyver, I. B.

Subjects
*NEURAL tube defects, *FETAL surgery, *PREGNANCY outcomes, *NEONATAL death, *GESTATIONAL age, *AGE differences
Abstract

Objective: In‐utero repair of open neural tube defects (ONTD) is an accepted treatment option with demonstrated superior outcome for eligible patients. While current guidelines recommend genetic testing by chromosomal microarray analysis (CMA) when a major congenital anomaly is detected prenatally, the requirement for an in‐utero repair, based on the Management of Myelomeningocele Study (MOMS) criteria, is a normal karyotype. In this study, we aimed to evaluate if CMA should be recommended as a prerequisite for in‐utero ONTD repair. Methods: This was a retrospective cohort study of pregnancies complicated by ONTD that underwent laparotomy‐assisted fetoscopic repair or open‐hysterotomy fetal surgery at a single tertiary center between September 2011 and July 2021. All patients met the MOMS eligibility criteria and had a normal karyotype. In a subset of the pregnancies (n = 77), CMA testing was also conducted. We reviewed the CMA results and divided the cohort into two groups according to whether clinically reportable copy‐number variants (CNV) were detected (reportable‐CNV group) or not (normal‐CMA group). Surgical characteristics, complications, and maternal and early neonatal outcomes were compared between the two groups. The primary outcomes were fetal or neonatal death, hydrocephalus, motor function at 12 months of age and walking status at 30 months of age. Standard parametric and non‐parametric statistical tests were employed as appropriate. Results: During the study period, 146 fetuses with ONTD were eligible for and underwent in‐utero repair. CMA results were available for 77 (52.7%) patients. Of those, 65 (84%) had a normal CMA and 12 (16%) had a reportable CNV, two of which were classified as pathogenic. The first case with a pathogenic CNV was diagnosed with a 749‐kb central 22q11.21 deletion spanning low‐copy‐repeat regions B–D of chromosome 22; the second case was diagnosed with a 1.3‐Mb interstitial deletion at 1q21.1q21.2. Maternal demographics, clinical characteristics, operative data and postoperative complications were similar between those with normal CMA results and those with reportable CNVs. There were no significant differences in gestational age at delivery or any obstetric and early neonatal outcome between the study groups. Motor function at birth and at 12 months of age, and walking status at 30 months of age, were similar between the two groups. Conclusions: Standard diagnostic testing with CMA should be offered when an ONTD is detected prenatally, as this approach has implications for counseling regarding prognosis and recurrence risk. Our results indicate that the presence of a clinically reportable CNV should not a priori affect eligibility for in‐utero repair, as overall pregnancy outcome is similar in these cases to that of cases with normal CMA. Nevertheless, significant CMA results will require a case‐by‐case multidisciplinary discussion to evaluate eligibility. To generalize the conclusion of this single‐center series, a larger, multicenter long‐term study should be considered. © 2023 International Society of Ultrasound in Obstetrics and Gynecology. [ABSTRACT FROM AUTHOR]

Published
2023
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9. Iatrogenic chorioamniotic separation and septostomy following fetoscopic laser photocoagulation for twin–twin transfusion syndrome

Author

Krispin, E., primary, Mustafa, H. J., additional, Sun, R. C., additional, Donepudi, R., additional, Espinoza, J., additional, Nassr, A. A., additional, Belfort, M. A., additional, Sanz Cortes, M., additional, Mostafaei, S., additional, Harman, C., additional, Turan, O., additional, and Shamshirsaz, A. A., additional

Published
2022
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11. Perinatal risk factors of neurodevelopmental impairment after fetoscopic laser photocoagulation for twin–twin transfusion syndrome: systematic review and meta‐analysis

Author

Hessami, K., primary, Nassr, A. A., additional, Sananès, N., additional, Castillo, J., additional, Castillo, H. A., additional, Sanz Cortes, M., additional, Espinoza, J., additional, Donepudi, R. V., additional, Sun, R. C., additional, Krispin, E., additional, Belfort, M. A., additional, and Shamshirsaz, A. A., additional

Published
2021
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13. OC17.01: Latrogenic chorioamniotic separation and septostomy following fetoscopic laser photocoagulation for Twin–twin transfusion syndrome

Author

Krispin, E., primary, Mustafa, H., additional, Sun, R., additional, Donepudi, R.V., additional, Espinoza, J., additional, Nassr, A., additional, Belfort, M.A., additional, Cortes, M. Sanz, additional, Mustafaei, S., additional, Harman, C., additional, Turan, O.M., additional, and Shamshirsaz, A., additional

Published
2021
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16. EP05.12: Prenatal imaging and clinical outcomes in isolated congenital aqueductal stenosis: a single‐centre retrospective cohort study.

Author

Sambatur, E., Qaderi, S., Soldatelli, M., Castillo, J., Castillo, H., Northam, W., Warf, B., Krispin, E., Grant, E., and Shamshirsaz, A.

Subjects
HYDROCEPHALUS, CHOROID plexus, CEREBRAL palsy, DEVELOPMENTAL delay, GESTATIONAL age, CEREBROSPINAL fluid shunts
Abstract

This article, titled "EP05.12: Prenatal imaging and clinical outcomes in isolated congenital aqueductal stenosis: a single-centre retrospective cohort study," explores the prenatal imaging measures, clinical course, and outcomes associated with isolated congenital aqueductal stenosis (CAS). CAS is a known cause of obstructive hydrocephalus and can lead to poor neurodevelopmental outcomes. The study included 22 patients with isolated CAS who were imaged prenatally and had at least one year of clinical follow-up. The findings indicate that there is a progressive increase in ventricular sizes from initial imaging to delivery, with most children requiring cerebrospinal fluid (CSF) diversion procedures and experiencing neurodevelopmental impairment. [Extracted from the article]

Published
2024
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