99 results
Search Results
2. Efficacy of High-Dose Nebulized Interferon α 2b in Severe COVID-19 Pneumonia.
- Author
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Chkhis, Ayman, Abdulrazzaq, Najiba, Mokhtar, Sherif, and Jasmi, Alia Al
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PNEUMONIA prevention ,THERAPEUTIC use of interferons ,PNEUMONIA ,COVID-19 ,CONFIDENCE intervals ,CHEST X rays ,MULTIVARIATE analysis ,RETROSPECTIVE studies ,INTERFERONS ,RISK assessment ,SEVERITY of illness index ,ARTIFICIAL respiration ,DESCRIPTIVE statistics ,AMINOTRANSFERASES ,LONGITUDINAL method - Abstract
OBJECTIVE: The COVID-19 pandemic is progressing rapidly, sending the world into a great panic. Healthcare professionals have responded by embarking on a concerted search for therapies to cure and prevent COVID-19. Recently, interferon (IFN) has emerged as a potential therapy as it is associated with reducing lung inflammation and suppressing viral replication. This research paper assessed the efficacy of high-dose nebulized IFN α 2b in severe COVID-19 pneumonia. METHODS: This is a retrospective study. It commenced on April 9 and ended on June 17, 2020. Researchers selected participants from hospitalized patients aged 18 years and above who were diagnosed with severe COVID-19 pneumonia. Other inclusion criteria were bilateral pneumonia on lung or chest X-ray scan and severe respiratory distress. SMART-COP, which is a risk stratification scoring tool, and radiologic severity index (RSI) were used to assess pneumonia severity. Patients in the treatment cohort received nebulized IFN α 2b at a dose of 10 million IU every 12 hours for 5 days, in addition to standard treatment. Patients in the control cohort received standard treatment only. RESULTS: Seventy-three patients met the inclusion criteria; 37 were included in the treatment cohort and 36 in the control cohort. Mechanical ventilation was needed in 14 of 36 (38.9%) patients in the control cohort, compared with 6 of 37 (27.4%) patients in the treatment cohort (HR 5.62 [95% CI 1.81-17.48]; P = .003). For pneumonia severity, there was a hazard ratio (HR) of 3.72 [95% CI 1.74-7.98]; P = ·.01. After 5 days of treatment, chest X-rays indicated significant beneficial changes in the treatment group (HR 2.24 [CI 1.05-4.79]; P = .036). Multivariate analysis revealed that pneumonia severity and RSI remained higher in the control group. The HR was 3.44 [95% CI 1.49-7.94]; P = .004 and 2.26 [95% CI 0.99-5.16]; P = .05, respectively. There was an increase in liver aminotransferases in 5 (14%) participants in the control cohort and 3 (8%) participants in the treatment cohort. CONCLUSION: High-dose nebulized IFN α 2b has potential efficacy in mitigating severe COVID-19 pneumonia. This study established that administering high-dose nebulized IFN α 2b significantly reduces pneumonia severity in COVID-19 patients. We also found a strong relationship between using nebulized IFN α 2b and reduced need for mechanical ventilation among patients with severe COVID-19 pneumonia. However, a well-designed control trial is needed to confirm the drug's efficacy in reducing the COVID-19 pneumonia severity. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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3. ARIA 2019, Allerjik Rinite Tedavi Yaklaşımı-Türkiye.
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Yorgancıoğlu, Ayşe Arzu, Gemicioğlu, Bilun, Cingi, Cemal, Kalaycı, Ömer, Kalyoncu, Ali Fuat, Bachert, Claus, Hellings, Peter, Pfaar, Oliver, Schünemann, Holger J., Wallace, Dana, Bedbrook, Anna, Czarlewski, Wienczyslawa, and Bousquet, Jean
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ALLERGIES ,ASTHMA ,DRUG therapy ,IMMUNOTHERAPY ,INTEGRATED health care delivery ,MEDICAL protocols ,MEDICAL societies ,RHINITIS ,PATIENT-centered care - Abstract
Copyright of Turkish Thoracic Journal / Turk Toraks Dergisi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
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4. Re: Pneumococcal and Influenza Vaccination Status of Hospitalized Adults With Community-Acquired Pneumonia and the Effects of Vaccination on Clinical Presentation.
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Bani, Waseem, Elmasry, Alshimaa, Perwaiz, Mohammad Ibrar, and Hussein, Faris
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VACCINATION status ,INFLUENZA vaccines ,PROFESSIONS ,PNEUMOCOCCAL vaccines - Published
- 2021
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5. Thoracic Aortic Aneurysm: A Rare Case Report.
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Duru, Serap, Erdem, Melike, Ağca, Erdem, Kaplan, Tuğba, and Ardıç, Sadık
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CHEST disease diagnosis ,AORTA ,THORACIC aneurysm diagnosis ,CHEST (Anatomy) ,CHEST X rays ,HOSPITAL admission & discharge ,EVALUATION of medical care ,PATIENTS ,OPERATIVE surgery ,TRANSPLANTATION of organs, tissues, etc. ,THORACIC aneurysms ,SYMPTOMS ,ANATOMY - Abstract
Copyright of Turkish Thoracic Journal / Turk Toraks Dergisi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2013
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6. A Pulmonary Tuberculosis Case Presented with Tonsillar Involvement.
- Author
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Kaya Kılıç, Esra and Kılıç, Caner
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Tonsillar tuberculosis is a rare form of extra pulmonary tuberculosis. We reported a case with tonsillar tuberculosis secondary to pulmonary tuberculosis in this paper. A 26 year old, unimmunocompromised man admitted to head and neck surgery clinic with complaints of fever, throatache and difficulty swallowing. The patient was consulted by infectious diseases clinic because of examination findings and his history. Asid fast basili was determined in tonsillar lesion smear, sputum and the patient was diagnosed as tonsillar and pulmonary tuberculosis. Antituberculous agents were started. Complaints of the patient were decreased and any adverse effect was developed. Treatment was completed in 9 months. In patients with long-term difficulty swallowing and fever, countries in which tuberculosis is prevalent, tonsillar tuberculosis should be considered, even if the patients were unimmunocompromised. [ABSTRACT FROM AUTHOR]
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- 2016
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7. Antibiotic Choices in an Outpatient Community with Acquired Respiratory Tract Infections in Turkey.
- Author
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Erdem, Hakan and Ünal, Serhat
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LUNG diseases ,RESPIRATORY diseases ,ANTI-infective agents ,ACUTE otitis media ,PNEUMONIA - Abstract
Copyright of Turkish Thoracic Journal / Turk Toraks Dergisi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2009
8. Two Cases of Tuberculosis Complicating Treatment With Tumor Necrosis Factor-α Inhibitors.
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Çalıkoğlu, Mukadder, Şahin, Günsah, and Aslan, Gönül
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INFLAMMATION ,ALIMENTARY canal inflammation ,ALVEOLITIS ,BURSITIS ,DISEASE susceptibility ,ETIOLOGY of diseases ,CONSTITUTIONAL diseases ,TUBERCULOSIS ,LUNG diseases ,MYCOBACTERIAL diseases - Abstract
Copyright of Turkish Thoracic Journal / Turk Toraks Dergisi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2008
9. Lober Karina Rezeksiyonu ve Rekonstrüksiyonu Yapılan Bir Karsinoid Tümör Olgusu.
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Okur, Erdal, Baysungur, Volkan, Gökçe, Mertol, and Halezeroğlu, Semih
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CARCINOID ,OPERATIVE surgery ,BRONCHI ,PRECANCEROUS conditions ,TUMORS - Abstract
Copyright of Turkish Thoracic Journal / Turk Toraks Dergisi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2010
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10. Pulmoner Alveoler Mikrolitiyazis.
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Fakılı, Füsun, Elbek, Osman, Kervancıoğlu, Reşat, İnan, Nilüfer, Tutar, Ediz, and Dikensoy, Öner
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PULMONARY alveoli ,CALCULI ,CHEST X rays ,ECHOCARDIOGRAPHY ,CALCIUM ,LUNG diseases ,DISEASES - Abstract
Copyright of Turkish Thoracic Journal / Turk Toraks Dergisi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2008
11. EDITORIAL.
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Bayram, Hasan and Dikensoy, Öner
- Abstract
An introduction is presented in which the editor discusses various reports within the issue on topics including research papers related to Neutrophil/Lymphocyte Ratio in COPD, Chronic Thromboembolic Pulmonary Hypertension and Respiratory Disability.
- Published
- 2016
12. The Knowledge and Attitude about New Generation Tobacco Products among Physicians.
- Author
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Bostan, Pınar and Dilektaşlı, Aslı Görek
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PROFESSIONS ,SMOKING cessation ,ELECTRONIC cigarettes ,CROSS-sectional method ,PHYSICIANS' attitudes ,SURVEYS ,QUESTIONNAIRES ,TOBACCO products ,SMOKING - Abstract
OBJECTIVE: Health hazards of e-cigarettes including "e-cigarette or vaping product use-associated lung injury" are better understood today. Just as e-cigarettes, heated tobacco products release toxic emissions. We aimed to determine the knowledge and attitude about new generation tobacco products among physicians who were the members of an organization for health care professionals, the majority of whom are pulmonologists. MATERIAL AND METHODS: In this cross-sectional study, a self-administered online questionnaire-based survey was conducted among the physicians from April to October 2019. The survey included questions about demographics (gender, age, graduation date from medical institution, and academic title), their smoking status, their knowledge and attitudes toward new generation tobacco products, and additionally about whether new generation tobacco products can be used to aid in smoking cessation. RESULTS: Among the 506 members who responded to the survey, 56.7 % were female; the mean age was 42.4 ± 10.9 years (20-74). About 74.5% were pulmonologists, 5.5% were thoracic surgeons, and 20% were other physicians. Among the responders, the frequency of those who have not heard of new generation tobacco products before was determined as 9.5%, 24.5%, and 41.3%. At least 58.9% of participants lacked the knowledge necessary to discuss these products with their patients and the rate reached 76.7% for the heated tobacco product. To the question of whether new generation tobacco products can be used in smoking cessation, 68.4% responded "I never agree that they can be used." Non-current smokers (P = .003), elders (P = .001), those who had training on smoking cessation assistance (P = .001), and those who had experience in smoking cessation assistance (P = .009) were significantly more prevalent in the group who answered: "I never agree that they can be used." CONCLUSION: Physicians must become considerably more knowledgeable about the new generation tobacco products and hazards. Otherwise, these new tobacco products may pose new threats to national and global tobacco control efforts. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
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13. Turkish Thoracic Society's Statement Report on Electronic Cigarettes and Heated Tobacco Products.
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Çetinkaya, Pelin Duru, Bostan, Pınar Pazarlı, Salepçi, Banu, Dilektaşlı, Aslı Görek, Elbek, Osman, Uyanusta Küçük, Filiz Çağla, Karadoğan, Dilek, Arpaz, Seren, Dülger, Seyhan, Uysal, Mehmet Atilla, Uzaslan, Esra, Özge, Cengiz, Kılınç, Oğuz, Dağlı, Elif, and Itil, Oya
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ELECTRONIC cigarettes ,GOVERNMENT policy ,TOBACCO products ,INFORMATION needs ,SMOKING ,MEDICAL societies ,TOBACCO ,SMOKING cessation products - Abstract
Tobacco addiction, which causes the death of more than 8.5 million people in the world every year, is a preventable global public health problem. There are 1.1 billion adult smokers worldwide and 60% of them desire or intend to quit but unfortunately, the tobacco industry continues to profit at the expense of people's lives by marketing electronic cigarettes and heated tobacco products as a smoking cessation method and they continue to poison young people with new threat tobacco products, promising a "smoke-free future" Turkish Thoracic Society is actively involved in the implementation of the National Tobacco Control Program to protect public health and has warned and raised awareness of new threats to the youth, such as electronic cigarettes and heated tobacco products. The purpose of this report is to provide information about electronic cigarettes and heated tobacco products and to present TTJ's position on the subject. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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14. A Scopus-Based Bibliometric Analysis of Global Tuberculosis Publications: 1849-2020.
- Author
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Merdan, Yağmur Ekenoğlu and Etiz, Pınar
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TUBERCULOSIS epidemiology ,TUBERCULOSIS prevention ,BIBLIOMETRICS ,WORLD health ,ELECTRONIC publications - Abstract
OBJECTIVE: Tuberculosis continues to become a serious public-health concern in many countries despite efforts to prevent and control global tuberculosis infections. MATERIAL AND METHODS: This study aims to present bibliometric analysis of the period 1849-2020 tuberculosis publications that are published by global researchers and indexed in the Scopus database. Although many studies have been carried out on tuberculosis, there is no study that performs bibliometric analysis of publications in this field in such a wide range of dates. Tuberculosis publications searched in the Scopus database between the period 1849-2020 were analyzed. Data on tuberculosis were presented by analyzing the number of publications, the language of publication, the countries that contribute the most to the literature, the most active institutions, the most cited publications, active authors and active journals, using appropriate quantitative and qualitative bibliometric indicators. RESULTS: 263,234 articles, published between 1849 and 2020 and searched in the Scopus database, were evaluated. The most articles (n= 8.344) were published in 2020. A total of 112,121 articles were published between 2001 and 2020. The most used publication language in the articles was English (62.48%), followed by Russian (7.25%). The country that contributed the most to the literature was the United States (13.81%), followed by India (7.18%). 3.9% of the articles were published in the journal "Tuberculosis and Lung Diseases". CONCLUSION: The results of the present bibliometric study are expected to shed light on the planning of future tuberculosis studies and the development of health policies toward tuberculosis. Research output is low in some countries, which should make larger investments in international and national collaborative research projects in the field of tuberculosis. If doing so, many countries of limited source will benefit from research that offer novel diagnostic and screening technology of tuberculosis. [ABSTRACT FROM AUTHOR]
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- 2022
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15. Is the Thoracic and Back Muscle Mass Associated with Disease Severity in Patients with COVID-19?
- Author
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Yığman, Zeynep Aykın, Umay, Ebru Karaca, Aktürk, Galip, and Ergün, Mustafa Çağrı
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BODY composition ,CHEST (Anatomy) ,RESPIRATORY muscles ,VIRAL pneumonia ,SKELETAL muscle ,COVID-19 ,SERRATUS anterior muscles ,INTERCOSTAL muscles ,ERECTOR spinae muscles ,BACK ,SEVERITY of illness index ,RISK assessment ,COMPARATIVE studies ,PECTORALIS muscle ,LATISSIMUS dorsi (Muscles) ,OXYGEN therapy ,THORACIC vertebrae ,TRACHEA intubation - Abstract
OBJECTIVE: With this study, it was aimed to investigate whether the thoracic muscle mass of patients with coronavirus disease 2019 was related to disease severity and disease characteristics and to evaluate whether muscle mass measurement had a predictive effect on predicting disease severity. MATERIAL AND METHODS: Two hundred twenty-three subjects (patient group = 161 and control = 62) who presented to our coronavirus disease 2019 outpatient clinic between May 2020 and September 2020 were included in the study. The medication, oxygen, and intubation requirements of the patients and their disease duration and hospital stay were also recorded. At the T4 level, thoracic and back (pectoralis, intercostalis, paraspinals, serratus, and latissimus dorsi) muscles and at the T12 level erector spinae muscles were measured in terms of area (cm²). RESULTS: T4-level muscle cross-sectional area results were found to be negatively correlated with the presence of pneumonia and the requirement of oxygen and intubation. In addition, both T4- and T12-level muscle cross-sectional area results were factors associated with oxygen and intubation requirements. T4-level muscle cross-sectional area results were also associated with the presence of pneumonia. CONCLUSION: We predict that there may be a relationship between the decrease in the mass of the accessory respiratory muscles and the severity of the disease. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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16. Six-Week Hospital-Based Pulmonary Rehabilitation in Covid Pneumonia ICU Survivors: Experience from a Tertiary Care Center in Central India.
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Khurana, Alkesh Kumar, Hussain, Aqeel, Goyal, Abhishek, Karna, Sunaina Tejpal, Saigal, Saurabh, Soman, Raj Krishnan, Verma, Mamta, Khadanga, Sagar, Sahu, Gaurav, and Singh, Brijendra
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MEDICAL rehabilitation ,PNEUMONIA ,INTENSIVE care units ,COVID-19 ,EXERCISE tolerance ,EVALUATION of human services programs ,LUNG diseases ,TERTIARY care ,HOSPITAL health promotion programs ,HUMAN services programs ,QUALITY of life ,QUESTIONNAIRES - Abstract
OBJECTIVE: There is very limited data on the usefulness of pulmonary rehabilitation in patients with coronavirus pneumonia who have survived intensive care unit care. The primary aim was to explore the feasibility of conducting a pulmonary rehabilitation program in patients with coronavirus disease-19 pneumonia surviving intensive care. The secondary aim was to study the impact of a hospital-based 6-week pulmonary rehabilitation program on exercise capacity, quality of life, and psychological parameters in these patients. This study was conducted at the Center for Pulmonary Rehabilitation, Department of Pulmonary Medicine of the institute. MATERIAL AND METHODS A total of 27 patients were enrolled. Among them, 14 patients who completed the desired 12 sessions over 6 weeks constituted the pulmonary rehabilitation group and 13 patients who either did not consent or defaulted within the first 2 weeks were considered as controls. Both groups had assessments at 0 and 6 weeks that included a 6-Minute Walk Test, Incremental Shuttle Walk Test, mMRC Dyspnea Scale, Baseline Dyspnea Index, and Transitional Dyspnea Index, Saint George's Respiratory Questionnaire score, and Depression, Anxiety, Stress Scale-21 score. RESULTS: Significant improvement in dyspnea by mMRC (P = .01) and exercise capacity as measured by 6-Minute Walk Test (P <.001) and Incremental Shuttle Walk Test (P = .025) was seen in the pulmonary rehabilitation group as compared to the control group. There was no significant improvement in quality of life and psychological parameters (Depression, Anxiety, Stress Scale 21 score) after 6 weeks of pulmonary rehabilitation program as measured in our study. CONCLUSION: Pulmonary rehabilitation is feasible and appears promising in coronavirus disease acute respiratory distress syndrome survivors. However, data from other centers and a larger number of patients are required to imbibe conclusive results. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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17. Turkish Thoracic Society Early Career Members Task Force Group's Virtual Congress Notes: European Respiratory Society International Congress 2020.
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Kızılırmak, Deniz, Karadoğan, Dilek, Yıldırım, Halime, Akyıl, Fatma Tokgöz, Eyüboğlu, Tuğba Şişmanlar, Emiralioğlu, Nagehan, Sertçelik, Ümran Özden, Günaydın, Fatma Esra, Ataoğlu, Özlem, Oğuz, Merve Sinem, Çakmakcı, Selin, Özçelik, Neslihan, Öncel, Aslı, Fırıncıoğluları, Ali, Kara, Bilge Yılmaz, Ömer, Dilara, Karaoğlanoğlu, Selen, Cetin, Nazli, Karakas, Fatma Gulsum, and Gurkan, Canan Gunduz
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CHEST diseases ,RESPIRATORY diseases ,COVID-19 ,LUNG diseases ,CONFERENCES & conventions ,RESPIRATORY infections ,LUNG tumors ,SLEEP disorders ,PULMONOLOGY ,VASCULAR diseases - Abstract
In this article, Early Career Task Force Group members of the Turkish Thoracic Society summarize the European Respiratory Society 2020 virtual congress. Current developments in the field of respiratory diseases were compiled with the addition of sessions specific to coronavirus disease 2019 this year. Almost all of the congress sessions were examined, and the important and striking results of the congress were highlighted. Congress sessions were attended by expert researchers, and the prominent messages of each session were highlighted in short summaries. They were then grouped under relevant titles and ranked in order of meaning and relation. It was finalized by a team of researchers. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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18. Pulmonary Rehabilitation in Coronavirus Disease 2019 Patients.
- Author
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Menekşeoğlu, Ahmet Kıvanç and Sindel, Dilşad
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MEDICAL rehabilitation ,COVID-19 ,LUNG diseases ,SEVERITY of illness index ,PERSONAL protective equipment ,COMORBIDITY - Abstract
Since coronavirus disease 2019 mainly affects the respiratory system, pulmonary rehabilitation has increased its importance during the novel coronavirus pandemic. Healthcare professionals must use appropriate personal protective equipment during rehabilitation of patients infected with severe acute respiratory syndrome coronavirus 2. Comorbidities of the patient should be taken into consideration while organizing the rehabilitation program. Clinical manifestations range from asymptomatic to acute respiratory distress syndrome. There is no need for pulmonary rehabilitation in asymptomatic patients. Pulmonary rehabilitation may be recommended in patients with mild-moderate disease. It is advised that patients be followed up during the rehabilitation period. Positioning and passive range of motion exercises are beneficial in preventing immobilization complications in patients with critical illness. Post-coronavirus disease 2019 rehabilitation program should be established according to the needs and functional levels of the patients. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
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19. COVID-19 Pneumonia After SARS-CoV-2 Vaccination with CoronaVac: A Case Series from Turkey.
- Author
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Çoban, Mehmet Meriç, Yakar, Mehmet Nuri, Küçük, Murat, Ergün, Bişar, Çelik, Muammer, Ergan, Begüm, Yaka, Erdem, and Gökmen, Necati
- Subjects
RISK factors of pneumonia ,COVID-19 ,CLINICAL trials ,COVID-19 vaccines ,DRUG design ,SYMPTOMS ,CASE studies - Abstract
Coronavirus disease 2019 is a novel viral infection that has caused a pandemic globally. Many kinds of vaccine development studies were conducted to prevent the spread and deaths. The CoronaVac is the most commonly used vaccine in Turkey. Phase 3 trials from various countries revealed that CoronaVac efficacy ranged from 50.7% to 91.25% but increased in moderate or severe cases to 100%. Additionally, it was remarkable owing to high seroconversion rates achieving up to 100%. After the vaccine campaign began in Turkey, critically ill patients continued to admit to our center's intensive care unit though they had been vaccinated with 2 doses of CoronaVac. The clinical course of these patients revealed that they are still at high risk of severe disease and death. Therefore, we aimed to share these patients' clinical characteristics and disease course, laboratory, and radiologic data. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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20. ERS International Virtual Congress 2021: Highlights from the Turkish Thoracic Society Early Career Members.
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Şenel, Merve Yumrukuz, Karadoğan, Dilek, Vardaloğlu, Ilgım, Develi, Elif, Çelik, Selma, Hızal, Mina, Özsezen, Beste, Öncel, Aslı, Can, İlknur, Hürsoy, Nur, Uyar, Kübra, Karakaş, Fatma Gülsüm, Er, Berrin, Asfuroğlu, Pelin, Gürsoy, Tuğba Ramaslı, Eyüboğlu, Tuğba Şişmanlar, Çakır, Eylül Pınar, Ademhan, Dilber, Karaoğlanoğlu, Selen, and Emiralioğlu, Nagehan
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TREATMENT of respiratory diseases ,PULMONOLOGISTS ,CONFERENCES & conventions ,MEMBERSHIP ,INFORMATION resources - Abstract
This review aimed to highlight some important points derived from the presentations of the European Respiratory Society 2021 Virtual International Congress by a committee formed by the Early Career Task Group of the Turkish Thoracic Society. We summarized a wide range of topics including current developments of respiratory diseases and provided an overview of important and striking topics of the congress. Our primary motivation was to give some up-to-date information and new developments discussed during congress especially for the pulmonologists who did not have a chance to follow the congress. This review also committed an opportunity to get an overview of the newest data in the diverse fields of respiratory medicine such as post-coronavirus disease 2019, some new interventional and technologic developments related to respiratory health, and new treatment strategies. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
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21. Altered Cardiac Repolarization in Chronic Obstructive Pulmonary Disease.
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Uğuz, Fatih Alper, Bozkuş, Fulsen, Aksu, Ekrem, Atilla, Nurhan, Kahraman, Hasan, and Doğaner, Adem
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HEART ,MANN Whitney U Test ,FISHER exact test ,T-test (Statistics) ,OBSTRUCTIVE lung diseases ,ELECTROCARDIOGRAPHY ,DESCRIPTIVE statistics ,CHI-squared test ,DEMOGRAPHY ,DATA analysis software ,LOGISTIC regression analysis ,DISEASE complications - Abstract
OBJECTIVE: Altered cardiac repolarization is an important mechanism in the development of malignant cardiac arrhythmia and in the occurrence of sudden cardiac death. It is known that the risk of cardiac arrhythmia and sudden death is increased in patients with chronic obstructive pulmonary disease. Evaluating the measurements of repolarization in the electrocardiogram may provide useful information to determine potential risks for lethal arrhythmias in the patients with chronic obstructive pulmonary disease. In the present study, we investigated the possible relationships between repolarization parameters in the electrocardio and demographic, clinical, and biochemical findings in patients with chronic obstructive pulmonary disease. MATERIAL AND METHODS: In the present study, 35 patients with Global Initiative for Chronic Obstructive Lung Disease A-B constituted group 1 and 35 patients with Global Initiative for Chronic Obstructive Lung Disease C-D constituted group 2. Cardiac repolarization and dispersion (QTc interval and QT dispersion) were measured on 12-lead electrocardiogram. QTc interval, QT dispersion, TP-e, and Tp-e/QTc were evaluated in order to determine the patients at risk of sudden cardiac death. QTc interval >440 ms in men and >460 ms in women was considered as prolonged QTc interval. RESULTS: QTc and QTd values were found to be statistically significantly prolonged in the group of GOLD C-D compared to the group of GOLD A-B (P < .001). QTc value showed negative correlation with the ratio of forced expiratory volume in 1 second to forced vital capacity and partial pressure of oxygen (P = .030, r = -0.260; P = .006, r = -0.332, respectively). No significant difference was in Tp-e and Tp-e/QTc between the groups (P = .73, P = .12, respectively). CONCLUSION: QTc and QTd are non-invasive markers reflecting arrhythmogenicity, and our findings were found to be related to prolonged QTc and QTd in patients with chronic obstructive pulmonary disease. Prolongation in the dispersion of repolarization and altered cardiac repolarization in the population with chronic obstructive pulmonary disease may be related to hypoxemia and airway obstruction. Alterations in the cardiac repolarization may put these patients at high risk for malignant ventricular arrhythmia and sudden cardiac death. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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22. Determination of Novel Coronavirus Disease (COVID-19) Vaccine Hesitancy Using a Systematic Review Approach Based on the Scientific Articles in PubMed Database.
- Author
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Ergün, Alperen, Bekar, Ayşegül, Aras, Bedran, Dere, Canan, Tekneci, Doğukan, Sarıçiçek, Gamze, Akdere, Selin Naz, Telli, Semi, Pehlivanlı, Şamil Berkay, Ucael, Deren Özyurek, Özden, Mustafa Enes, Altıntaş, Ercüment, and Aslan, Dilek
- Subjects
ONLINE information services ,COVID-19 vaccines ,SYSTEMATIC reviews ,MEDLINE - Abstract
OBJECTIVE: Publications on vaccine hesitancy and the novel coronavirus disease 2019 in the scientific literature are increasing every day. An examination of their content will help to eliminate the existing negativity related to vaccine hesitancy through scientific methods. Hence, a systematic approach to the prevention of vaccine hesitancy worldwide can be developed. This article aims to survey how vaccine hesitancy is addressed in the PubMed articles about "vaccine hesitancy" over the novel coronavirus disease, for which the MeSH criteria have been published; to understand their recommendations for the prevention of vaccine hesitancy; to evaluate any related research described as "cross-sectional," "case-control," and "cohort" according to Strengthening the Reporting of Observational Studies in Epidemiology criteria; and to contribute to the current literature on the subject. MATERIAL AND METHODS: This study is planned to use a systematic review format and STROBE checklist was used to evaluate the articles accessed from PubMed database. Microsoft Excel was used as the data calculation tool. RESULTS: Sixty-five (81.3%) of the 80 articles investigated in the scope of this study mention "vaccine." While 64 articles (80%) discuss the determination of vaccine hesitancy, 57 (71.3%) articles address its prevention. The keyword "COVID-19" is used in 61 articles (79.2%). The second most frequently used keyword is "vaccine hesitancy" (n = 37, 48.1%), followed by "vaccine" (n = 25, 32.5%). Twenty-nine (48%) of the reviewed articles originate from the WHO American Continents. The second most represented region of research is the European Region (n = 21, 35%), followed by the South East Asian Region (n = 5, 8%). CONCLUSION: This study illustrates the recent situation for the coronavirus disease 2019 vaccine and reveals the presence of a vaccine hesitancy. Vaccine hesitancy is a risk factor that could prevent herd immunity. The systematic review of scientific articles should continue with improvements in order to tackle the problem as exemplified by the present study. Other checklists as well as STROBE checklist are recommended to be used in similar studies to have more objective conclusions. [ABSTRACT FROM AUTHOR]
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- 2022
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23. Comparison of Different Slice Thicknesses on Chest Computed Tomography for Evaluation of COVID-19-Associated Pneumonia.
- Author
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Atasoy, Dilara, Çetinkaya, Nazım, Çaylak, Halil, Sarıismailoğlu, Rağıp, and Atalar, Mehmet Haydar
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VIRAL pneumonia ,REVERSE transcriptase polymerase chain reaction ,COVID-19 ,PREDICTIVE tests ,CHEST X rays ,RESEARCH evaluation ,TIME ,SEVERITY of illness index ,COMPARATIVE studies ,INTER-observer reliability ,COMPUTED tomography ,POLYMERASE chain reaction ,DATA analysis software ,EVALUATION - Abstract
OBJECTIVE: To compare the value of chest computed tomography at 1-mm and 5-mm slice thickness in terms of computed tomography severity score and computed tomography evaluation time in the diagnosis of COVID-19. MATERIAL AND METHODS: Sixty-five patients were included in the study group who are reverse-transcription polymerase chain reaction-positive for COVID-19 and had chest computed tomography. The 1 mm and 5 mm reconstructed images were evaluated in 2 different sessions with 4-week intervals by 2 certificated general radiologists. The presence of COVID-19-related findings, COVID-19 final category, and evaluation time were recorded. Thin and thick slices were compared for these variables and inter-reader reliability calculated with the Statistical Package for the Social Sciences (SPSS) for Windows. RESULTS: There was no significant difference between the COVID-19-related findings on thorax computed tomography between 1-mm and 5-mm slices except crazy paving appearance, microvascular enlargement, and septal thickening. The frequency of the final categories of computed tomography results was consistent between the thick and thin slices. The computed tomography assessment time was significantly lower in 5 mm slices. The inter-reader reproducibility analysis results demonstrated good and excellent reproducibility of measurements between readers for both slice thicknesses. CONCLUSION: It was found that 5-mm reconstruction thickness of chest computed tomography can be employed for the initial detection of COVID-19-related findings and the final diagnostic category-related COVID-19 rather than 1-mm slices with a faster availability of results which can be beneficial on pandemic hospitals. [ABSTRACT FROM AUTHOR]
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- 2022
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24. Persistent Ambient Air Pollution in Turkey: A 4-Year Analysis.
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Aykaç, Nilüfer and Yasin, Yeşim
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AIR pollution ,PARTICULATE matter ,ENVIRONMENTAL monitoring ,RESEARCH methodology - Abstract
OBJECTIVE: Ambient air pollution is an important cause of morbidity and mortality for both individual and public health. The major contaminant that creates air pollution in Turkey is particulate matter. This study aims to demonstrate Turkey's air quality in terms of particulate matter in the last 4 years. MATERIAL AND METHODS: In this descriptive study, the public data of the National Air Quality Monitoring Network between the years 2016 and 2019 were analyzed for particulate matter (PM
10 ). Stations with less than 75% data throughout the year were excluded from the evaluation while calculating the annual average values. The averages of the years were compared statistically with each other. RESULTS: For 111 stations that made sufficient measurements for 4 years, the annual median value of particulate matter remained constant in 12 stations (10.8%), increased in 26 stations (23.4%), and decreased in 73 stations (65.7%). The level of air pollution at 18 stations has been sustained for 4 years. It has been observed that there is no significant improvement in the criterion that the daily average PM10 level should not be higher than 50 µg/m³ for more than 35 days, and pollution is detected above the limit value permitted by the World Health Organization in all provinces and stations except a few provinces every year. Finally, during the 4-year observation, the number of stations that did not make sufficient measurements throughout the year has been found to increase over the years. CONCLUSION: Our data reveal that the air pollution attributable to particulate matter in Turkey between the years 2016 and 2019 did not regress prominently. On the contrary, air pollution has been found to gain permanency in certain provinces, and air quality monitoring has been inadequate due to insufficient measurement activities of some of the stations. [ABSTRACT FROM AUTHOR]- Published
- 2021
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25. Regular Treatment With Aspirin 300 mg/day After Desensitization in Patients With N-ERD: 12-Year Results.
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Kaya, Saltuk Buğra, Çakmak, Mehmet Erdem, Damadoğlu, Ebru, Karakaya, Gül, and Kalyoncu, Ali Fuat
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DRUG therapy for asthma ,DISEASE relapse prevention ,ALLERGY desensitization ,RESPIRATORY diseases ,DRUG efficacy ,NASAL polyps ,ORAL drug administration ,NONSTEROIDAL anti-inflammatory agents ,TREATMENT duration ,COMPARATIVE studies ,ASPIRIN ,PULMONARY function tests ,QUALITY of life ,DESCRIPTIVE statistics ,DRUG allergy ,DISEASE exacerbation ,ENDOSCOPY ,LONGITUDINAL method ,EVALUATION - Abstract
OBJECTIVE: Aspirin desensitization is recommended for patients with nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity, in whom asthma is uncontrolled despite medical treatment, and/or frequent endoscopic sinus surgery (ESS) is required due to nasal polyps. There are few studies in the literature on long-term follow-up of patients undergoing regular aspirin treatment after desensitization. This study aims to evaluate the effect of regular aspirin treatment on respiratory function, symptom control, quality of life, and the number of nasal surgeries required during a period of 12 years. MATERIAL AND METHODS: A total of 18 patients were included in the study in 2006; 11 patients were excluded and 7 patients regularly taking aspirin for 12 years were evaluated. Oral aspirin desensitization was performed at 4-6 weeks following the ESS. Patients receiving 300 mg/day aspirin were followed up in control visits every 3 months. Nasal and respiratory system examinations and pulmonary function test were performed, and all patients responded to the SF-36 Quality of Life scale during each visit. RESULTS: There was no change in respiratory function parameters following the12-year aspirin treatment. There was no statistically significant improvement in the quality of life; however, the need for ESS due to the recurrence of nasal polyps decreased significantly (P = .000). At the 12-year follow-up, all symptom scores improved, but improvement in the postnasal drip score was statistically significant (P = .046). CONCLUSION: Long-term regular treatment with aspirin at a dose of 300 mg/day in patients with N-ERD improved symptom scores, and alleviated the need for ESS due to nasal polyp recurrence. [ABSTRACT FROM AUTHOR]
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- 2021
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26. Adult Primary Antibody Deficiencies and the Lung.
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Damadoğlu, Ebru
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PROFESSIONS ,ASTHMA ,INTERSTITIAL lung diseases ,RESPIRATORY infections ,IMMUNOLOGICAL deficiency syndromes ,OBSTRUCTIVE lung diseases ,BRONCHIECTASIS ,IMMUNOLOGIC diseases ,EARLY diagnosis ,ADULTS - Abstract
Primary antibody deficiency diseases result from a genetic defect that causes misfunction of 1 or more of the immune system elements. Due to the increased awareness among physicians and the success of new treatment modalities, the number of pediatric patients reaching adult age and the number of patients diagnosed in adult age is increasing. Adult patients comprise more than half of the total cases. Primary antibody deficiencies are the most common immunodeficiency type in adults, and these may cause recurrent upper and lower respiratory tract infections and result in the development of bronchiectasis. Among non-infectious pulmonary complications, any type of interstitial lung disease may be seen; however, a special type seen in patients with common variable immunodeficiency, namely granulomatous lymphocytic interstitial lung disease, is the one most commonly investigated. Underlying or accompanying immunodeficiency may be present in patients with asthma and chronic obstructive pulmonary disease, especially if the disease requires frequent hospitalizations and/or is severe. Early diagnosis and appropriate management of primary antibody deficiency diseases in patients with respiratory symptoms are crucial to decrease complications and increase survival. [ABSTRACT FROM AUTHOR]
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- 2021
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27. Vacuum Bell: Is It a Useful Innovative Device for Pectus Excavatum Correction?
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Loufopoulos, Ioannis, Karagiannidis, Ioannis G., Lampridis, Savvas, Mitsos, Sofoklis, and Panagiotopoulos, Nikolaos
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STERNUM abnormalities ,CARDIAC surgery ,PECTUS excavatum ,CHEST X rays ,ENDOSCOPIC surgery ,SYSTEMATIC reviews ,DATABASE searching ,STERNUM ,LUNG diseases ,DIFFUSION of innovations - Abstract
Pectus Excavatum (PE) or "funnel chest," the most common deformity of the anterior chest wall characterized by sternal depression, can be repaired via either operative or non-invasive techniques. Vacuum Bell (VB) device is the most widespread of the latter one which can be applied either intraoperatively or as monotherapy. The present narrative review examines the efficacy of that innovative method. A thorough search of the literature resulted in 13 English-written articles concerning VB therapy from its first description to February 2019. The studies included patients with mild to moderate PE, mainly evaluated via Haller-Index and/or sternum depth prior to and following treatment. Concerning depth-improvement, 37-90% showed amelioration while 10-40% of them an excellent correction to normal. In 42%, Haller-Index also improved with a median decrease of 0.3 after VB application. A correlation was attempted to be found between the efficacy of VB and factors such as the frequency and duration of VB application, patient age, gender, PE severity and type, and differential pressure of the suction cup. Complications may be frequent yet mild and temporary. Intraoperatively, VB widows Minimally Invasive Repair of Pectus Excavatum (MIRPE) operation a safer procedure with greater results. VB as conservative treatment is an effective and well-tolerated alternative therapeutic option for selected patients with PE who meet specific criteria. It also constitutes a device of significant efficacy, appropriate for intraoperative use during MIRPE procedure. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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28. Inhalation Challenge Tests in Occupational Asthma: Why Are Multiple Tests Needed?
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Üzmezoğlu, Bilge Akgündüz
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PREDICTIVE tests ,RESPIRATORY disease diagnosis ,OCCUPATIONAL exposure ,BRONCHIAL provocation tests ,ATTRIBUTION (Social psychology) ,OCCUPATIONAL asthma - Abstract
Occupational and environmental lung diseases are on the rise because of the widespread use of various toxic agents in industry. Asthma etiopathogenesis is unclear because of exposure to high and low molecular agents in workplaces. Approximately 15-25% of asthma in adults is reported to be related to occupational exposure. The prevalence of occupational asthma (OA) is predicted to be high. The difficulties in diagnosing OA results in inadequate treatment, permanent airway damage, and medicolegal and social problems. As with other occupational diseases, it is necessary to demonstrate a direct causal relationship between the suspected agent and OA. Spirometry, peak expiratory flow rate, and/or non-specific bronchial hyperresponsiveness are frequently used to show airway hyperresponsiveness at the workplace and away from work. However, there are some controversies about the specificity and sensitivity of these test methods. Furthermore, these tests do not identify the exposure agent, which could be the causative agent. Specific inhalation challenge (SIC) tests that demonstrate the direct causal relationship are currently the gold standard. However, their positive and negative predictive values have not yet been established; therefore, many low molecular weight agents could cause late or atypical reactions. Therefore, a negative SIC test cannot exclude the disease. This review describes the procedures for the SIC test and discusses the importance of using the combined test methods with the SIC test. [ABSTRACT FROM AUTHOR]
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- 2021
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29. Sleep Quality Among Healthcare Workers During the COVID-19 Pandemic and Its Impact on Medical Errors: Kuwait Experience.
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Abbas, Ahmad, Al-Otaibi, Torki, Gheith, Osama Ashry, Nagib, Ayman Maher, Farid, Mahmoud M., and Walaa, Mohammad
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HEALTH facility employees ,CROSS-sectional method ,MEDICATION errors ,SLEEP ,MEDICAL errors ,RISK assessment ,SLEEP disorders ,PSYCHOSOCIAL factors ,DESCRIPTIVE statistics ,DRUG allergy ,COVID-19 pandemic - Abstract
OBJECTIVE: Millions of people suffer from sleep disturbances. In addition, the coronavirus disease 2019 (COVID-19) pandemic created several new challenges--particularly for frontline healthcare workers (HCWs). This study assessed the sleep quality (SQ) among HCWs. MATERIAL AND METHODS: A cross-sectional study was conducted using an English-language online survey. The participants were invited via a web link sent using social network platforms. It included sociodemographic- and profession-related characteristics. COVID-19-associated risks were assessed (e.g., being on the front line, doing swabs, satisfaction about protective equipment, and management protocols). Assessment of SQ was done using the Pittsburgh Sleep Quality Index (PSQI) and various medical errors were recorded. RESULTS: A total of 217 HCWs completed the survey with mean (±standard deviation) age of 35.8 (±7.3) years; 56.2% were male, 18.43% had comorbidities, and 61.75% experienced sleep difficulties before the COVID-19 crisis. This work reports a 78.8% prevalence of poor SQ, with the mean (standard deviation) global PSQI score of 9.36 (±4.4). HCWs with poor sleep experienced more positive comorbid profile (23.64% versus 6.52%, p=0.01). Working on the front lines of COVID-19 was associated with poor sleep (69.59% versus 47.83%, p=0.006). Among the participants, 77.42% performed medical errors, particularly not checking for drug allergies (17.97%), dispensing medication with incomplete instructions (20.74%), providing incorrect doses or overdosing (14.75%), incorrectly explaining the use of medication (9.22%), and prescribing a drug to the wrong patient (10.14%). CONCLUSION: This nationwide survey reported high prevalence of poor SQ among HCWs during the COVID-19 pandemic. Being an HCW on the front lines of COVID-19 and doing swabs with a positive comorbidity was associated with poor sleep. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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30. A case of carcinoid tumor who underwent lobar carina resection and reconstruction.
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Okur E, Baysungur V, Gokce M, and Halezeroglu S
- Abstract
Carcinoid tumors are low-grade malignant lesions of the bronchial system. Complete surgical resection is proposed, saving as much lung parenchyma as possible for treatment. Our patient had a typical carcinoid tumor located at the division of the left upper and lower lobar bronchus. We completely resected and reconstructed the lobar carina invaded by tumor without resecting any lung parenchyma. Although it is technically demanding, lobar carina resection, reported in a limited number of papers in the literature, can be successfully performed in appropriate cases, [ABSTRACT FROM AUTHOR]
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- 2010
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31. COVID-19 Pandemic and the Global Perspective of Turkish Thoracic Society.
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Köktürk, Nurdan, İtil, Bahriye Oya, Altınışık, Göksel, Adıgüzel, Nalan, Akgün, Metin, Akyıldız, Levent, Altın, Sedat, Arıkan, Hüseyin, Ateş, Güngör, Ay, Pınar, Aykaç, Nilüfer, Babayiğit, Cenk, Bostan, Pınar, Cinel, Güzin, Çalışır, Haluk Celaleddin, Çelik, Pınar, Çetinkaya, Pelin Duru, Dağlı, Elif, Demir, Ahmet Uğur, and Demir, Canan
- Subjects
EDUCATION of physicians ,CHEST diseases ,HEALTH policy ,MEDICAL societies ,PUBLIC health ,HEALTH & social status ,COVID-19 ,COVID-19 pandemic - Abstract
It has been more than 3 months now since the first case of COVID-19 was reported in Turkey. Globally, the number of confirmed cases and deaths reached 9,653,048 and 491,128 respectively, as reported by 216 countries by June 27, 2020. Turkey had 1,396 new cases, 194,511 total cases, and 5,065 deaths by the same date. From the first case until today, the Turkish Thoracic Society (TTS) has been very proactive in educating doctors, increasing public awareness, undertaking academic studies, and assisting with public health policies. In the present report, social, academic, and management perspectives of the pandemic are presented under appropriate subtitles. During this critical public health crisis, TTS has once again demonstrated its readiness and constructive stance by supporting public health, healthcare workers, and the environment. This review summarizes the perspective of TTS on each aspect of the COVID-19 pandemic and casts light on its contributions. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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32. Covid-19: The Biggest Threat of the 21st Century: In Respectful Memory of the Warriors All Over the World.
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Karcıoğlu, Oğuz, Yüksel, Aycan, Baha, Ayşe, Er, Aslıhan Banu, Esendağlı, Dorina, Gülhan, Pınar Yıldız, Karaoğlanoğlu, Selen, Erçelik, Merve, Şerifoğlu, İrem, Yıldız, Ethem, and Köktürk, Nurdan
- Subjects
POLYMERASE chain reaction ,DIAGNOSTIC errors ,COVID-19 pandemic - Abstract
Since the first case was diagnosed in China, the new coronavirus infection (COVID-19) has become the number one issue in the world and it seems to remain trend-topic for a long time. Until 17 April, it affected 210 countries, infected over 2 million people and caused approximately 150000 deaths. Although the course of the disease ranges from asymptomatic state to severe ARDS; the majority of patients reveal only mild symptoms. Though adults are the most commonly affected group; it can also be seen in newborns and elderly patients. Unfortunately, elderly patients are the most vulnerable group with higher mortality. Elderly patients, smokers and patients with comorbid conditions are most affected by the disease. In certain diagnostical tool is the real-time reverse transcription-polymerase chain reaction (real-time RT-PCR) test. However, it can be resulted in false-negative results and in this case the computed thorax tomography (CT) is one of the most important tools with high sensitivity. Besides the supportive treatment, most commonly used agents are immunomodulatory drugs such as plaquenil and azitromycin, and anti-virals including oseltamivir, ritonavir-lopinavir, favipiravir. Until a vaccine or a specific therapy invented, the most important intervention to control the disease is to fight against transmission. This is a real war and the doctors are the soldiers. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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33. The Underminers: Booming Illicit Trade of Roll Your Own and Waterpipe Tobacco in Turkey.
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Uznay, Fatih and Gümüş, Sevtap
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COMMERCIAL law ,LEGAL status of sales personnel ,TOBACCO ,GOVERNMENT policy ,GOVERNMENT regulation ,TOBACCO products ,DESCRIPTIVE statistics - Abstract
OBJECTIVES: The aim of this study is to specify the reasons and extents of illicit Roll-Your-Own (RYO) and waterpipe tobacco (WPT) markets which broke out in Turkey and to determine the destruction of these markets over the effectiveness of main tobacco control measures, the effect of this destruction on increase in tobacco use and the measures that can be taken. MATERIALS AND METHODS: Reliable data about illicit trade are quite limited. This study was prepared through using the recommended methods on illicit trade in "Methods for Evaluating Tobacco Control Policies" published by the International Agency For Research On Cancer (IARC) and "Understand, Measure, and Combat Tobacco Smuggling" published by the World Bank. RESULTS: RYO and WPT markets are almost totally illicit in Turkey. These markets serve to tobacco outbreak by increasing total tobacco use far beyond the official data through its size surpassing 30% of total consumption and they have begun to invalidate all of the principle tobacco control measures by hindering and undermining them. CONCLUSION: In order to implement tobacco control measures effectively in Turkey, these illicit markets must be included in system by doing necessary regulations promptly. It is strongly needed that illicit RYO and WPT production and trade should be described as newly emerged threat areas in tobacco control literature, since other countries may suffer from similar problems. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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34. What We Learned about COVID-19 So Far? Notes from Underground.
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Akyıl, Fatma Tokgöz, Karadoğan, Dilek, Gürkan, Canan Gündüz, Yüksel, Aycan, Arıkan, Hüseyin, Eyüboğlu, Tuğba Şişmanlar, Emiralioğlu, Nagehan, Gürsoy, Tuğba Ramaslı, Şerifoğlu, İrem, Töreyin, Zehra Nur, Marim, Feride, Kara, Bilge Yılmaz, Özakıncı, Hilal, Develi, Elif, Çakmakçı, Selin, Küsbeci, Tuba Çiftçi, Karcıoğlu, Oğuz, Gülhan, Pınar Yıldız, Erçelik, Merve, and Er, Berrin
- Subjects
THERAPEUTIC use of protease inhibitors ,ANGIOTENSIN converting enzyme ,CARDIOVASCULAR diseases ,CELL receptors ,CHLOROQUINE ,COUGH ,FEVER ,GENETIC techniques ,HYPERTENSION ,POLYMERASE chain reaction ,PROFESSIONS ,SMOKING ,COMORBIDITY ,FIBRIN fibrinogen degradation products ,LOPINAVIR-ritonavir ,NUCLEOSIDE reverse transcriptase inhibitors ,COVID-19 - Abstract
The novel coronavirus pandemic poses a major global threat to public health. Our knowledge concerning every aspect of COVID-19 is evolving rapidly, given the increasing data from all over the world. In this narrative review, the Turkish Thoracic Society Early Career Taskforce members aimed to provide a summary on recent literature regarding epidemiology, clinical findings, diagnosis, treatment, prevention, and control of COVID-19. Studies revealed that the genetic sequence of the novel coronavirus showed significant identity to SARS-CoV and MERS-CoV. Angiotensin-converting enzyme 2 receptor is an important target of the SARS-CoV-2 while entering an organism. Smokers were more likely to develop the disease and have a higher risk for ICU admission. The mean incubation period was 6.4 days, whereas asymptomatic transmission was reported up to 25 days after infection. Fever and cough were the most common symptoms, and cardiovascular diseases and hypertension were reported to be the most common comorbidities among patients. Clinical manifestations range from asymptomatic and mild disease to severe acute respiratory distress syndrome. Several patients showed typical symptoms and radiological changes with negative RT-PCR but positive IgG and IgM antibodies. Although radiological findings may vary, bilateral, peripherally distributed, ground-glass opacities were typical of COVID-19. Poor prognosis was associated with older age, higher Sequential Organ Failure Assessment score, and high D-dimer level. Chloroquine was found to be effective in reducing viral replication in vitro. Likewise, protease inhibitors, including lopinavir/ritonavir, favipiravir, and nucleoside analogue remdesivir were proposed to be the potential drug candidates in COVID-19 management. Despite these efforts, we still have much to learn regarding the transmission, treatment, and prevention of COVID-19. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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35. Turkish Thoracic Society Experts Consensus Report: Recommendations for Pulmonary Function Tests During and After COVID 19 Pandemic.
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Gemicioğlu, Bilun, Börekçi, Şermin, Dilektaşlı, Aslı Görek, Ulubay, Gaye, Azap, Özlem, and Saryal, Sevgi
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CLINICAL pathology equipment ,PREVENTION of epidemics ,PREVENTION of infectious disease transmission ,ATTITUDE (Psychology) ,CHEST diseases ,PREVENTION of communicable diseases ,CONSENSUS (Social sciences) ,EXPERTISE ,MEDICAL appointments ,MEDICAL personnel ,MEDICAL protocols ,PERSONAL protective equipment ,REPORT writing ,PULMONARY function tests ,STERILIZATION (Disinfection) ,MEDICAL triage ,VENTILATION ,COVID-19 - Abstract
The recommendation of conducting pulmonary function tests (PFTs) from different societies during and after the coronavirus disease (COVID-19) pandemic was rated by the experts of the Turkish Thoracic Society (TTS) and presented as the TTS experts consensus report. Information about the topic has been provided. Globally, as of mid-May 2020, there have been over 4.4 million confirmed cases of COVID-19. There are two main routes of transmission of COVID-19: respiratory droplets and contact transmission. PFTs are non-invasive tests that are commonly performed in routine assessment and follow-up of patients in the pulmonology units. However, PFTs may generate aerosols and require sharing common surfaces. With regard to the high prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the community, PFTs should not be performed routinely in confirmed or suspected patients with COVID-19 during the pandemic. Because of the risk of human-to-human transmission of COVID-19, PFTs should be restricted to a small patient population with selected indications. Triage for COVID-19 should be performed prior to testing. Only essential PFTs such as spirometry, diffusion capacity of the lungs for carbon monoxide (DLCO), arterial blood gas analysis, or pulse oximetry should be performed in the selected cases. Tests should be scheduled to allow sufficient time for donning and doffing of the technical personnel with the full personal protective equipment (PPE) (gown, a filtering respirator mask, goggles or full-face shield, and disposable gloves), ventilation of the room, and application of post-test cleaning and disinfection procedures of the equipment and the testing room. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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36. Call for Emergency Action to Limit Global Temperature Increases, Restore Biodiversity, and Protect Health.
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Atwoli, Lukoye, Baqui, Abdullah H., Benfield, Thomas, Bosurgi, Raffaella, Godlee, Fiona, Hancocks, Stephen, Horton, Richard, Laybourn-Langton, Laurie, Monteiro, Carlos Augusto, Norman, Ian, Patrick, Kirsten, Praities, Nigel, Rikkert, Marcel G. M. Olde, Rubin, Eric J., Sahni, Peush, Smith, Richard, Talley, Nicholas J., Turale, Sue, and Vázquez, Damián
- Subjects
PUBLIC health ,CONFERENCES & conventions ,ENVIRONMENTAL health ,PAIN catastrophizing ,CLIMATE change ,BIOTIC communities ,COVID-19 pandemic - Published
- 2021
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37. EDITORIAL.
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Bayram, Hasan and Kılınç, Oğuz
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CHEST diseases ,MEDICAL practice ,PHYSICIANS ,SERIAL publications - Abstract
An introduction to the journal is presented in which the editors discuss various reports published within the issue, including one on factors that affect the success of smoking cessation initiatives, one on the impact of smoking on the success in the treatment of multiple drug resistance tuberculosis and another on the attitudes of school teachers towards smoking.
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- 2013
38. Anti-IL-5 Biologicals Targeting Severe Late Onset Eosinophilic Asthma.
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Özyiğit, Leyla Pur, Öztürk, Ayşe Bilge, and Bavbek, Sevim
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ASTHMA ,EOSINOPHILIA ,INTERLEUKINS ,MONOCLONAL antibodies ,DISEASE exacerbation ,DELAYED onset of disease - Abstract
Improved knowledge about the pathogenesis of asthma has facilitated the development of novel drugs and provided hope for patients with severe asthma. After the short- and long-term success of omalizumab in severe allergic phenotype, researchers have targeted patients with severe eosinophilic asthma who comprise up to 45% of adult severe asthma. Interleukin (IL)-5 and IL-5 receptor subunit α play crucial roles in the development, maturation, and operation of eosinophils. Currently, patients treated with anti-IL-5 biologicals depleting eosinophils experience the positive efficacy of these drugs, especially with regard to the reduction of exacerbation rate. The aim of this review was to shed light on severe eosinophilic asthma treatment with these new currently available agents selectively targeting IL-5 or its receptor, discussing their usage including pre-treatment concerns, such as selecting the target population and choosing the right agent among them, and subsequent assessment of relevant effect and safety issues. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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39. Does the Hospital Admission of Patients with Respiratory Disease Increase in Izmir When the PM10 Level is High?
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Yalnız, Enver, Uslu, Özgür, Bolat, Erkut, Altın, Sedat, and Polat, Gülru
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AIR pollution ,ASTHMA ,BRONCHIECTASIS ,DYSPNEA ,HOSPITAL care ,RESPIRATORY diseases ,RHINITIS ,SEX distribution ,DESCRIPTIVE statistics - Abstract
OBJECTIVES: Air pollution is caused by exhaust emissions from motor vehicles, fuel consumption for heating of residences, and especially emissions from industrial facilities around the world. The exposure to outdoor air pollution has been associated with acute and chronic health problems, from irritation to death. In this study, we aimed to determine whether air pollution increases the frequency of hospital admission and whether there is a difference between disease subgroups, age, and gender, in the 2-year period in Izmir province where - air pollution is increasing. MATERIALS AND METHODS: Collection of health data for the project compiled by the Ministry of Health, in cooperation with the Izmir Provincial Health Directory Information Processing Department, and information obtained on the age groups, gender, admission time, and diagnosis of illness [International Classification of Diseases (ICD)10 code] on the residents of Izmir in 2016/2017. RESULTS: The daily numbers of patients with respiratory complaints and air pollution were found to be related. Both air pollution and the admission rate increase in the January--March period. In male patients, the risk of hospitalization increases for 1.14%. Males had a higher increase in the rate of diagnosis of chronic rhinitis (increase of 6.22%) than females who had an increase of 0.97%. It was observed that there was a 2.62% increase in the incidence of bronchiectasis, 2.53% in that of asthma, and 2.49% in that of dyspnea. CONCLUSION: There was a significant increase in respiratory diseases during the days when the air pollution was high, and this was observed as the upper respiratory tract infection and acute bronchitis in the young group and chronic respiratory diseases in the elderly group upon hospital admissions. The reduction of air pollutants and inhalation of clean air are the most important aspects in providing a healthier and longer life. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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40. Correlation between the Diagnostic Yield from the Bronchoalveolar Lavage Fluid Analysis and Clinicoradiological Findings in Sarcoidosis.
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Akyıl, Fatma Tokgöz, Ağca, Meltem, Öztürk, Hatice, Sonkaya, Esin, Erdem, İpek, Bülbül, Esra Usta, Özbaki, Fatma, Yıldız, Reyhan, Bekir, Sümeyye Alparslan, and Sevim, Tülin
- Subjects
BODY fluid analysis ,SARCOIDOSIS diagnosis ,ACADEMIC medical centers ,BRONCHOALVEOLAR lavage ,CHEST X rays ,COMPUTED tomography ,SCIENTIFIC observation ,RETROSPECTIVE studies ,DESCRIPTIVE statistics ,CD4 lymphocyte count ,LYMPHOCYTE count - Abstract
OBJECTIVES: The diagnosis of sarcoidosis is frequently challenging, requiring a search for less invasive, more reliable diagnostic methods. The bronchoalveolar lavage fluid (BALF) analysis has been used in the differential diagnosis of sarcoidosis for many years with a wide sensitivity and specificity rates. The objective of the study is to investigate whether diagnostic performance of the BALF analysis is altered by clinicoradiological findings of patients with sarcoidosis. MATERIALS AND METHODS: The present study is a retrospective, single-center, observational study, designed in a sarcoidosis outpatient clinic in a training hospital. Patients who had undergone the bronchoalveolar lavage BAL procedure at diagnosis were included in the study. Demographics, clinical and detailed chest X-ray, and high-resolution computed tomography (HRCT) findings at diagnosis were recorded. According to the diagnostic performance, the BALF results were grouped as "diagnostic" and "non-diagnostic," and recorded parameters were compared between the groups. RESULTS: Considering the BALF analysis of all the 257 patients, the mean lymphocyte ratio was 41±17.5 (5--80), and the mean CD4/CD8 was 5.5±4.7 (0.1-24.7). The BALF analysis was diagnostic in 56% (n=145) of patients. Diagnostic performance of the procedure did not correlate with any of the demographic data, smoking status, spirometric findings, chest X-ray staging, HRCT findings, and tomography scoring. Extrapulmonary involvement was significantly more frequent in the diagnostic group (66% vs. 34%, p=0.006). CONCLUSION: BALF results signal sarcoidosis in more than half of the patients. The diagnostic role of BALF is greater in patients with extrapulmonary involvement. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
41. Work-Related Symptoms of Patients with Asthma: A Multicenter Study.
- Author
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Mungan, Dilşad, Özmen, İpek, Evyapan, Fatma, Topçu, Füsun, Akgün, Metin, Arbak, Peri, and Bülbül, Yılmaz
- Subjects
ASTHMA diagnosis ,ALLERGIES ,ASTHMA ,CLEANING compounds ,DUST ,GASES ,INDUSTRIAL hygiene ,MEDICAL cooperation ,OCCUPATIONAL diseases ,OCCUPATIONS ,QUESTIONNAIRES ,RESEARCH ,SODIUM hypochlorite ,WORK environment ,OCCUPATIONAL hazards ,ENVIRONMENTAL exposure ,CROSS-sectional method ,DISEASE exacerbation ,DESCRIPTIVE statistics ,OCCUPATIONAL asthma - Abstract
OBJECTIVES: It is considered that occupational exposure accounts for up to 25% of all cases of adult asthma. We need detailed individual-level data regarding the relationship between asthma, occupation, and work-related symptoms in Turkey to inform policies on workplace safety. This study aimed to investigate the association between asthma symptoms, occupation type, and workplace exposure in patients with asthma. MATERIALS AND METHODS: In this cross-sectional multicenter study, adult patients with asthma were investigated by a questionnaire in terms of relationship between asthma symptoms and workplace exposure. The study population was adult patients who had been diagnosed with asthma for at least six months prior to study and who were under follow-up in Ankara, İstanbul, Erzurum, Düzce, Trabzon, Denizli, and Diyarbakır. RESULTS: The mean age of the 345 cases (188 females) was 41±13 years. The majority of the patients (36.8%) were "housewives"; other common occupations were office workers (6.7%), textile workers (4%), students (3.8%), hospital staff (3.5%), and cleaners (2.9%). Thirty-five percent of patients described worsening of asthma during working periods. Among patients with a history of increased symptoms in workplace, 100 (83%) developed asthma after starting work, while 20 patients (17%) had pre-existing asthma. Half of the patients described workplace exposure to dust, fume, and gases. Exposure to cleaning supplies at home was present in 43% of the subjects. Of all housewives, 12% (n=15) described an increase in their asthma symptoms during housework. The frequency of bleach or hydrochloric acid use alone among housewives was 60% and 34%, which was significantly higher than other occupations. The FEV
1 /FVC ratio of housewives who frequently used hydrochloric acid (FEV1 /FVC=71.5) was lower than that of non-users (FEV1 /FVC=74.9) (p=0.024). CONCLUSION: Patients with asthma experience significant workplace exposures that exacerbate their symptoms. Housewives experience significant exposure that triggers allergic and asthma symptoms. It is important to raise awareness about the prevalence and risks of occupational (including in-home) exposures in asthmatics patients and physicians to minimize asthma triggers and exacerbations. [ABSTRACT FROM AUTHOR]- Published
- 2019
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42. Airway Clearance with Expiratory Flow Accelerator Technology: Effectiveness of the "Free Aspire" Device in Patients with Severe COPD.
- Author
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Patrizio, Giorgia, D'Andria, Michele, D'Abrosca, Francesco, Cabiaglia, Antonella, Tanzi, Fabio, Garuti, Giancarlo, and Nicolini, Antonello
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OBSTRUCTIVE lung disease treatment ,TREATMENT of respiratory obstructions ,AIRWAY (Anatomy) ,THERAPEUTIC use of breathing exercises ,CONFIDENCE intervals ,QUALITY of life ,RESPIRATORY infections ,T-test (Statistics) ,TECHNOLOGY ,PILOT projects ,RANDOMIZED controlled trials ,TREATMENT effectiveness ,DATA analysis software ,DESCRIPTIVE statistics ,POSITIVE end-expiratory pressure ,MANN Whitney U Test ,DISEASE risk factors - Abstract
OBJECTIVES: Chronic obstructive pulmonary disease (COPD) is associated with a higher risk of pulmonary infections. This risk not only negatively affects patients' quality of life but also increases social and health costs. Hence, there is a need for an effective rehabilitative treatment including airway clearance. The aim of this pilot study was to evaluate the efficacy of a new tool for bronchial clearance based on expiratory flow accelerator (EFA) technology compared with positive expiratory pressure (PEP) treatment. MATERIALS AND METHODS: Twenty stable patients with COPD, Global Initiative for Chronic Obstructive Lung Disease 3-4 stage, were enrolled and allocated to treatment with EFA or Bubble-PEP (BP) for 20 days during a pulmonary rehabilitation program. At baseline and the end of treatment, the following parameters were measured: arterial blood gases (ABG); respiratory function, including peak cough expiratory flow (PCEF), maximal inspiratory pressure (MIP), and maximal expiratory pressure exercise capacity using the 6-minute walk test (6MWT), dyspnea using the Medical Research Council scale, and quality of life using the St. George's Respiratory Questionnaire. RESULTS: Expiratory flow accelerator showed a significant pre- and post-improvement in ABG and a significantly greater improvement than BP in PCEF, MIP, and 6MWT post-treatment. CONCLUSION: Expiratory flow accelerator is a valid device compared with BP as an adjunctive therapy for the treatment of patients with severe COPD. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
43. Comparison of Compliance Rates and Treatment Efficiency in Home-Based with Hospital-Based Pulmonary Rehabilitation in COPD.
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Pehlivan, Esra, Yazar, Esra, Balcı, Arif, and Kılıç, Lütfiye
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COMPARATIVE studies ,EXERCISE therapy ,HOME care services ,LONGITUDINAL method ,LUNG diseases ,OBSTRUCTIVE lung diseases ,MEDICAL rehabilitation ,PATIENT compliance ,TREATMENT effectiveness - Abstract
OBJECTIVES: The aim of the present study was to compare the home-based pulmonary rehabilitation (PR) with the hospital-based PR with respect to exercise compliance rates and efficiency of therapy in stable chronic obstructive pulmonary disease (COPD). MATERIALS AND METHODS: Patients with stable severe and very severe COPD who were admitted consequently to our PR clinic were prospectively included in the study. Patients who completed the home-based PR for at least 4 days/week for 2 months as recommended were classified as the study group. Patients who completed the hospital-based PR in our clinic before the present study were classified as the control group. RESULTS: Thirty-five patients were included in the home-based PR, but 10 patients were incompatible with the exercise training, and four patients were out of follow-up. Twenty-one patients successfully completed the home-based PR (study group), and compliance rate was 60%. Thirty-seven patients previously underwent the hospital-based PR, and 25 patients completed the exercise program (control group); thus, their compliance rate was 67%. There was no difference between the two groups with respect to treatment compliance rates. The significant improvement in six-minute walking distance, modified Medical Research Council dyspnea, and COPD Assessment Test scores were observed after PR in both groups, and there was no difference with respect to the levels of improvement. CONCLUSION: The present study showed that approximately two-thirds of patients with COPD successfully completed the home-based PR, and that this program also provided similar benefits with respect to the quality of life and exercise capacity compared with the hospital-based PR. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
44. Rationale and Design of the Turkish Sleep Apnea Database -- TURKAPNE: A National, Multicenter, Observational, Prospective Cohort Study.
- Author
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Peker, Yüksel, Başoğlu, Özen K., and Fırat, Hikmet
- Subjects
SLEEP apnea syndromes ,SLEEP apnea syndrome treatment ,ACADEMIC medical centers ,ALCOHOLISM ,ANTHROPOMETRY ,BIOMARKERS ,BLOOD sugar ,CARDIOVASCULAR diseases ,ECHOCARDIOGRAPHY ,LIPIDS ,LONGITUDINAL method ,LUNG diseases ,MEDICAL cooperation ,METABOLIC disorders ,SCIENTIFIC observation ,QUESTIONNAIRES ,RESEARCH ,PULMONARY function tests ,SMOKING ,SUBSTANCE abuse ,TRAFFIC accidents ,PHENOTYPES ,COMORBIDITY ,POLYSOMNOGRAPHY ,EDUCATIONAL attainment ,PROFESSIONAL licenses ,CROSS-sectional method ,ADVERSE health care events ,ADULTS ,GENETICS ,DIAGNOSIS - Abstract
OBJECTIVES: The primary aim of The Turkish Sleep Apnea Database (TURKAPNE) study is to generate a cross-sectional nationwide database for defining the clinical and polysomnographic characteristics of the patients with obstructive sleep apnea (OSA) in Turkey. MATERIALS AND METHODS: In this ongoing project, all consecutive adults with suspected OSA are recruited from the sleep centers of the university and research hospitals in Turkey. Information on anthropometric data, educational status, driving license, smoking habits, alcohol use, comorbidities, drug use, questionnaires, polysomnographic, and/or cardiorespiratory polygraphic findings are recorded in a systematized Web-based report form. Blood glucose, lipids and other biochemical markers, lung function, and echocardiography measurements are optionally included. Follow-up data regarding treatment modality and compliance is assessed. Cross-sectional and longitudinal associations between OSA phenotypes and metabolic, pulmonary, and cardiovascular comorbidities as well as traffic accidents, and the impact of treatment will be further explored. We target a total sample of 10,000 participants. RESULTS: The study was registered with ClinicalTrials.gov (NCT02784977) in May 2016 and the first patient was recruited in October 2017. A total of 1911 participants from 19 centers have been enrolled in the study by May 31, 2018. CONCLUSION: The TURKAPNE study will contribute to a better understanding of the health-related burden of OSA phenotypes and its association with the comorbidities and adverse outcomes, including traffic accidents in Turkey. The results may also contribute to a more personalized approach and better management of varying OSA phenotypes with concomitant disorders. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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- View/download PDF
45. Assessing the Prevalence and Incidence of Asthma and Chronic Obstructive Pulmonary Disease in the Eastern Mediterranean Region.
- Author
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Masjedi, Mohammadreza, Ainy, Elaheh, Zayeri, Faried, and Paydar, Rogayeh
- Subjects
ASTHMA ,CONFIDENCE intervals ,OBSTRUCTIVE lung diseases ,MEDLINE ,META-analysis ,ONLINE information services ,SYSTEMATIC reviews ,DISEASE incidence ,DISEASE prevalence ,CHRONIC bronchitis - Abstract
OBJECTIVES: This study conducted in 2016 aimed to assess the prevalence and incidence of asthma and chronic obstructive pulmonary disease (COPD) in the Eastern Mediterranean Region (EMR). MATERIAL AND METHODS: A meta-analysis to evaluate the published research relating to asthma and COPD was conducted using data from 23 EMR Office (EMRO) countries and searching using the web of science, PubMed, SciVerse Scopus, Google scholar, and MEDLINE databases. The keywords entered were all EMRO countries (Afghanistan, Bahrain, Djibouti, Egypt, Islamic republic Iran, Iraq, Jordan, Kuwait, Lebanon, Libyan Arab Jamahiriya, Morocco, Oman, Pakistan, Palestine, Qatar, Saudi Arab, Somalia, Sudan, Syrian Arab Republic, Tunisia, the United Arab Emirates, Yemen republic, and Cyprus) and asthma OR chronic obstructive pulmonary disease (COPD) OR (chronic bronchitis). Our definition of asthma and COPD was according to the World Health Organization (WHO). RESULTS: A total of 92 published articles were identified. The pooled prevalence of asthma and COPD was 9.38 (confidence interval [CI]: 9.20-9.55) and 5.39 (CI: 5.17-5.62), respectively. There were no articles about COPD and asthma in Bahrain and Djibouti; no articles about asthma in Jordan and Libyan Arab Jamahiriya; and no articles about COPD in Afghanistan, Iraq, Oman, Palestine, Somalia, Sudan, and Yemen republic. The highest prevalence of asthma was observed in Kuwait, and the highest prevalence of COPD was observed in Pakistan. CONCLUSION: The EMRO countries have inadequate research and data in the areas of asthma and COPD. More efforts and relevant studies must be conducted to understand the countrywide prevalence and real burden of these diseases. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
46. The Effect of Smoking on the Course of Tuberculosis.
- Author
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Yalçınsoy, Murat, Güngör, Sinem, Begüm Afşar, Bigen, Bilgin, Sevinç, and Akkaya, Esen
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TUBERCULOSIS treatment ,SMOKING ,SMOKING cessation ,TUBERCULOSIS - Abstract
A letter to the editor is presented in response to the article "The Relation of Smoking With Treatment Success in Cases With Multi Drug-Resistant Tuberculosis," by P. Pazarli et al, in a 2013 issue.
- Published
- 2014
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47. A Prospective Review of the Results of Patients Treated and Followed up for a Diagnosis of Sarcoidosis.
- Author
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Özdemir, Levent and Özdemir, Burcu
- Subjects
SARCOIDOSIS diagnosis ,SARCOIDOSIS treatment ,PATIENT aftercare ,LONGITUDINAL method ,MUSCLE diseases ,PUBLIC hospitals ,SARCOIDOSIS ,STEROIDS ,TREATMENT effectiveness - Abstract
OBJECTIVES: The present study reports the treatment and follow-up results of patients prospectively diagnosed and treated in a public hospital. MATERIAL AND METHODS: The present study reports the prospective follow-up data of 21 sarcoidosis cases followed up and treated in the Department of Chest Diseases of Dörtyol State Hospital from January 2010 to December 2014 RESULTS: The 21 cases had a mean age of 44±10 years and a mean follow-up period of 38±13 months. While 10 cases were given steroid treatment, 11 cases were radiologically followed up. Besides pulmonary involvement, skin findings were detected in 7 cases and ophthalmologic findings were detected in 3 cases. In the treatment group, regression was observed in the radiographic findings of 6 cases, while no radiologically significant changes were seen in 4 cases. In the follow-up group, regression was observed in the radiographic findings of 9 cases, while no significant changes were seen in mediastinal LAPs of 2 cases. At the end of the treatment, it was found that 1 case developed steroid-induced myopathy, 1 case developed fungus ball of the sequelae, 1 case had loss of vision secondary to posterior uveitis, and 1 case had a risk of steroid-induced osteoporosis. CONCLUSION: Choice of treatment procedure based on the stage and clinical results of the patient is still the most effective method in sarcoidosis treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
48. Respiratory Disability in The Van Region Based on the Medical Board Reports.
- Author
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Mermit Çilingir, Buket
- Abstract
OBJECTIVES: Respiratory system disorders have an impact on daily living activities of subjects, resulting in disability. Data should be gathered on disability for health services. The present study aimed to review the records of patients with a respiratory disability report from our medical board, and contribute to the national and regional statistics on disability. MATERIAL AND METHODS: We retrospectively reviewed sociodemographic characteristics, respiratory diseases and disability rates of the patients who were examined by the Chest Diseases Department during the Medical Board evaluations in our hospital between January 1st and July 1st, 2014. RESULTS: Among 4285 patients whose applications were submitted to the medical board for evaluation, 401 (9.3%) had a respiratory disease. Of these patients, 163 were male, and 238 were female, with a mean age of 64.2 years. The most common diseases associated with disability were chronic obstructive pulmonary disease, asthma and sequelae tuberculosis.The disability rating for respiratory system was 80% in 24.9% of patients, 40% in 34.7% of patients, and 20% in 40.4% of patients. Patients with a respiratory disability report were also considered disabled by the departments of Physical Therapy and Rehabilitation, Cardiology and Eye diseases. There was a positive correlation between disability rating and age, and a negative correlation between forced expiratory volume in first second (FEV
1 ) and oxigen saturation measured by pulse oximeter (SpO2 ) values (p= 0.002; p< 0.001; p< 0.001, respectively). Furthermore, smokers had a higher disability rating compared to non-smokers (p= 0.02). CONCLUSION: In Turkey, we have limited number of studies about respiratory disability. We believe that the present study will help determination of the etiology of respiratory disability and contribute to any action on prevention of these disorders in our region. [ABSTRACT FROM AUTHOR]- Published
- 2016
- Full Text
- View/download PDF
49. The Importance of Neutrophil-to-Lymphocyte Ratio in Chronic Obstructive Pulmonary Disease.
- Author
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İn, Erdal, Kuluöztürk, Mutlu, Öner, Önsel, and Deveci, Figen
- Subjects
BLOOD sedimentation ,BLOOD cell count ,C-reactive protein ,INFLAMMATION ,OBSTRUCTIVE lung diseases ,LYMPHOCYTES ,NEUTROPHILS ,RESPIRATORY measurements ,SERUM ,VITAL capacity (Respiration) ,CASE-control method ,RECEIVER operating characteristic curves - Abstract
OBJECTIVES: Chronic obstructive pulmonary disease (COPD) is a common lung disease characterized by airflow limitation and systemic inflammation. Recently, neutrophil-to-lymphocyte ratio (NLR) has gathered increasing interest in the detection of inflammation in inflammatory diseases. This study aimed to investigate the role of NLR in COPD for identifying the detection of inflammation and recognition of acute exacerbation. MATERIAL AND METHODS: The laboratory results of 103 COPD patients were included into the study, of which 47 patients were in acute exacerbation and 56 patients were at stable period, and there were 40 gender and age-matched healthy controls. Complete blood count (CBC), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were evaluated. NLR was calculated from CBC. RESULTS: NLR values of patients with COPD (both acutely exacerbated and stable) were found significantly higher than those of the controls (p< 0.001, p< 0.05; respectively). In all patients with COPD, NLR values positively correlated with serum CRP (r= 0.641, p< 0.001) and ESR (r= 0.276, p= 0.005) levels and negatively correlated with forced vital capacity (r= -0.20, p= 0.043) and forced expiratory volume in the 1st second (r= -0.288, p= 0.003). For an NLR cutoff of 3.34, sensitivity for detecting exacerbation of COPD was 78.7% and specificity was 73.2% (AUC 0.863, p< 0.001). CONCLUSION: Our results suggest that NLR may be considered as a reliable and simple indicator in the determination of increased inflammation in patients with COPD. Furthermore, NLR could be useful for the early detection of possible acute exacerbations in patients with COPD. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
50. EDITORIAL.
- Subjects
DATABASE evaluation ,CHEST diseases - Abstract
An introduction is presented in which the editor discusses various articles within the issue on topics including lung function in children, and asthma monitoring and training program on children's disease management.
- Published
- 2015
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