1. [Comparative morphometric study of the ultrastructure of cells in vivo and in vitro].
- Author
-
Iagubov AS and Kats VA
- Subjects
- Adenoviridae, Animals, Cells, Cultured, Cricetinae, Cytoplasm ultrastructure, Endoplasmic Reticulum ultrastructure, Fibroblasts ultrastructure, Lymphoma, Large B-Cell, Diffuse pathology, Mitochondria ultrastructure, Neoplasm Transplantation, Organoids ultrastructure, Rats, Sarcoma, Experimental pathology, Cells ultrastructure
- Abstract
A morphometrical study of the fine structure of normal and malignant cells, both taken immediately from the organism (in vivo) or previously cultured (in vitro) was carried out. A high level on the mitochondrial morphological coefficient -- Km was discovered in normal and malignant cells in vitro. Unlike, the ergastoplasmic morphological coefficient -- Ke was high in the in vivo cells and low in the in vitro cells. The in vitro factor causes considerable changes in the fine structure of cells, which are more important than distinctions between normal and malignant cells. This fact must be taken into account in morphological studies of cells in vitro.
- Published
- 1975