1. Pre-mRNA splicing in yeast
- Author
-
John Abelson and Stephanie W. Ruby
- Subjects
Genetics ,Splice site mutation ,Base Sequence ,RNA Splicing ,Molecular Sequence Data ,Alternative splicing ,Exonic splicing enhancer ,Intron ,RNA, Fungal ,Saccharomyces cerevisiae ,Group II intron ,Biology ,Catalysis ,Introns ,Cell biology ,Fungal Proteins ,Exon ,Splicing factor ,RNA splicing ,RNA Precursors ,Nucleic Acid Conformation - Abstract
The removal of introns from the primary transcript occurs by RNA splicing. Three major types of RNAs: tRNA, rRNA and mRNA, are known to contain introns. There are two general questions concerning any splicing mechanism: first, how is the precise recognition and alignment of the splice junctions achieved in introns whose lengths vary from a few hundred nucleotides to several thousands of nucleotides and, second, what are the biochemical mechanisms of the cleavage and ligation reactions.
- Published
- 1991
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