Search

Sensors and biosensors have been increasingly used for clinical analysis due to their miniaturization and portability, allowing the construction of diagnostic devices for point-of-care testing. This paper presents an up-to-date overview and comparison of the analytical performance of sensors and biosensors recently used in clinical analysis. This includes cancer and cardiac biomarkers, hormones, biomolecules, neurotransmitters, bacteria, virus and cancer cells, along with related significant advances since 2011. Some methods of enhancing the analytical performance of sensors and biosensors through their figures of merit are also discussed., (© 2016 Elsevier B.V. All rights reserved.)

We provide a state-of-the-art review of the main strategies for the enhancement of analytical performance of sensors using nanomaterials, particularly nanowires and carbon-based materials. We emphasize the way to overcome the problem of device-to-device variation. We discuss the study of the influence of nanomaterial characteristics, sensor dimensions and operational conditions on sensing performance, and the application of appropriate calibration models., (Copyright © 2013 Elsevier Ltd. All rights reserved.)