1. Factor Analysis for Body Mass Index Changes in Kidney Transplant Recipients
- Author
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Soojinna Choi, Yeon-Ho Han, Sang-Hoon Shin, Seok Jun Sohn, Ho-Kyun Lee, and Hyo-Sin Kim
- Subjects
medicine.medical_specialty ,Statin ,medicine.drug_class ,Logistic regression ,Kidney transplant ,Body Mass Index ,chemistry.chemical_compound ,Risk Factors ,Internal medicine ,Hyperlipidemia ,medicine ,Humans ,Aged ,Transplantation ,Cholesterol ,business.industry ,Odds ratio ,Middle Aged ,medicine.disease ,Kidney Transplantation ,Confidence interval ,Transplant Recipients ,chemistry ,Surgery ,business ,Factor Analysis, Statistical ,Body mass index - Abstract
Background The purpose of this study was to identify factors influencing changes in the body mass index (BMI) of kidney transplant (KT) patients and provide data for the management of the BMI of patients who have undergone KT. Method The participants were 106 patients who underwent KT at a single center from August 2014 to June 2017. BMIs were compared and analyzed for 6 months and 24 months after KT, and the survey details were collected through medical records. Analysis was performed between 2 groups, one with increased BMI and the other without. Multivariate logistic regression analysis was performed to identify the factors related to an increase in BMI. Results BMI increased from 22.60 ± 2.72 kg/m2 at 6 months to 23.18 ± 3.06 kg/m2 2 years after KT. The group with increased BMI (n = 39) had more patients with higher low-density cholesterol levels at the time of KT (low-density cholesterol ≥100 mg/dL; 34 [54.0%] vs 10 [26.3]; P = .008) and without statin drug use than the other group (n = 67) (statin drug use, 48 [70.6%] vs 34 [87.2%], P = .044). Multiple logistic regression analysis showed that age >50 years (odds ratio [OR] = 2.942; 95% confidence interval [CI], 1.075-8.055; P = .036), low-density lipoprotein >100 mg/dL at KT (OR = 6.618; 95% CI, 2.225-19.682; P = 0.001), and no statin drugs (OR = 5.094; 95% CI, 1.449-17.911, P = .011) were the risk factors for an increased BMI after KT. Conclusions After KT, to prevent an increase in the BMI, clinicians should strongly recommend the use of drugs to treat hyperlipidemia, especially in elderly patients with high low-density lipoprotein levels before KT.
- Published
- 2021