Search

Your search keyword '"Foca A"' showing total 121 results
Start Over Author "Foca A" Journal transplantation proceedings
121 results on '"Foca A"'

8. Infectious tolerance mediated by CD8+ T-suppresor cells after UV-B-irradiated donor-specific transfusion and rat heart transplantation

Author

Piotr Witkowski, Nicole Suciu-Foca, Jiawang Liu, Mark A. Hardy, Ming-Xing Jin, and Zhuoru Liu

Subjects
Adoptive cell transfer, Time Factors, Ultraviolet Rays, medicine.medical_treatment, education, T-Lymphocytes, Regulatory, Andrology, Medicine, Animals, Transplantation, Homologous, Blood Transfusion, Heart transplantation, Transplantation, business.industry, Graft Survival, CD28, Rat heart, Adoptive Transfer, In vitro, Rats, Rats, Inbred ACI, Rats, Inbred Lew, Lymphocyte Transfusion, Immunology, Heart Transplantation, Surgery, Transplantation Tolerance, business, CD8, Heart allograft
Abstract

Aims. CD8+CD28- human T-suppressor cells (Ts), which can be generated in vitro, act directly on APC rendering them tolerogenic to unprimed and primed CD4+ T cells. The aim of this study was to investigate the possibility that CD8+ T cells mediate the induction of tolerance in a heart transplantation model in rodents. Materials and Methods. Blood from Lewis rats was UV-B-irradiated and transfused into ACI recipients on days -21, -14, and -7 before heart allograft transplantation on day 0. CD4 + and CD8 + T cells were positively selected from ACI rats, which had tolerated Lewis heart allografts for more than 100 days and were adoptively transferred to naive ACI rats pretreated (day -1) with gamma irradiation. These ACI rats underwent transplantation with Lewis hearts 24 hours after adoptive transfer of putative T-suppressor cells. Results. Adoptive transfer of CD8 + T cells from tolerant ACI to naive ACI rats significantly prolonged Lewis heart mean allograft survival time (MST ′ SD) to 69 ′ 13 days as compared with 15 ′ 1 and 14 ′ 1 days in animals adoptively transferred with CD4+ T cells or untreated controls, respectively (P

Published
2005

15. Persistent allopeptide reactivity and epitope spreading in chronic rejection

Author

Adriana I. Colovai, Emily Rose, Nicole Suciu-Foca, Eric K. Ho, Rodica Ciubotariu, Raffaello Cortesini, and Aurica Foca-Rodi

Subjects
Graft Rejection, Isoantigens, Transplantation, Cellular immunity, Coronary Disease, Biology, Virology, Epitope, Postoperative Complications, Immune system, Antigen, Risk Factors, Immunology, Heart Transplantation, Humans, Surgery, Reactivity (psychology), Epitope spreading
Published
1999
Full Text
View/download PDF

16. CD8(+)CD28(-) T suppressor cells represent a distinct subset in a heterogeneous population

Author

Adriana I. Colovai, Raffaello Cortesini, Zhuoru Liu, Rodica Ciubotariu, and Nicole Suciu-Foca

Subjects
Genetics, Transplantation, medicine.diagnostic_test, Cell Cycle, T lymphocyte, Cell cycle, Biology, Cd8 cd28, CD8-Positive T-Lymphocytes, Flow Cytometry, Lymphocyte Activation, Flow cytometry, Cell Line, Immunophenotyping, Immune system, Antigen, Cell culture, T-Lymphocyte Subsets, medicine, Humans, Surgery
Published
2001

17. Allospecific T-suppressor cells in liver transplantation

Author

Eric K. Ho, Paola Cinti, B Evangelista, E. R. Molajoni, N Suciu Foca Cortesini, Raffaello Cortesini, F. Della Pietra, Massimo Rossi, M Iapelli, and M.T Lonardo

Subjects
Graft Rejection, Transplantation, T suppressor, Immunity, Cellular, business.industry, medicine.medical_treatment, Down-Regulation, T lymphocyte, T-Lymphocytes, Helper-Inducer, Liver transplantation, T-Lymphocytes, Regulatory, Liver Transplantation, HLA Antigens, Immunology, medicine, Humans, Surgery, business
Published
2001

18. CD8(+)CD28(-) T cells suppress alloresponse of CD4(+) T cells both in primates and rodents

Author

Jianshe Fan, Nicole Suciu-Foca, Raffaello Cortesini, B Yu, and Zhuoru Liu

Subjects
Transplantation, Cellular immunity, Cell, Dose-Response Relationship, Immunologic, Rats, Inbred WF, T lymphocyte, Cd8 cd28, Biology, T-Lymphocytes, Regulatory, In vitro, Rats, Rats, Inbred ACI, Immune system, Animal model, medicine.anatomical_structure, Established cell line, Immunology, Models, Animal, medicine, Animals, Transplantation, Homologous, Surgery, Transplantation Tolerance, Papio
Published
2001

19. Tacrolimus as cornerstone immunosuppressant in kidney transplantation

Author

N Sociu-Foca Cortesini, Raffaello Cortesini, R. Pretagostini, P.B. Berloco, and Massimo Rossi

Subjects
Graft Rejection, Transplantation, medicine.medical_specialty, business.industry, Calcineurin Inhibitors, Hypercholesterolemia, Drug Resistance, medicine.disease, Kidney Transplantation, Risk Assessment, Tacrolimus, Surgery, Acute Disease, medicine, Cyclosporine, Humans, Steroids, Vascular Diseases, business, Kidney transplantation, Immunosuppressive Agents, Follow-Up Studies
Published
2001

20. Experimental and clinical tolerance induction

Author

Nicole Suciu-Foca, Mark A. Hardy, and S Agrawal

Subjects
Graft Rejection, Immunosuppression Therapy, Transplantation, Isoantigens, business.industry, Histocompatibility Antigens Class II, Organ Transplantation, Kidney Transplantation, Peptide Fragments, Tissue Donors, Immune tolerance, Rats, Tolerance induction, medicine.anatomical_structure, Immunology, Immune Tolerance, Medicine, Animals, Humans, Surgery, Bone marrow, business, Bone Marrow Transplantation
Published
1998

21. Contribution of the direct and indirect allorecognition pathway to the rejection of liver allografts

Author

A.M Orlandini, E Renna-Molajoni, J Molajoni, B Evangelista, Paola Cinti, P. Cocciolo, Nicole Suciu-Foca, and Raffaello Cortesini

Subjects
Graft Rejection, Cellular immunity, Isoantigens, medicine.medical_treatment, T-Lymphocytes, Biology, Liver transplantation, Methylprednisolone, Mice, Azathioprine, medicine, Animals, Humans, Transplantation, Homologous, Allorecognition, Cells, Cultured, Transplantation, Graft rejection, Flow Cytometry, Liver Transplantation, Immunoglobulin G, Immunology, Cyclosporine, Surgery, Immunosuppressive Agents
Published
1998

24. Mapping of dominant HLA-DR determinants recognized via the indirect pathway

Author

Zhuoru Liu, Nicole Suciu-Foca, F. Gargano, Adriana I. Colovai, Sorina Tugulea, Raffaello Cortesini, E. R. Molajoni, Antonella Maffei, M. A. Hardy, Paul L. Harris, and Elaine Reed

Subjects
Transplantation, Cellular immunity, Isoantigens, T-Lymphocytes, T lymphocyte, HLA-DR Antigens, Biology, Indirect pathway of movement, Peptide Mapping, Epitope, Peptide Fragments, Major Histocompatibility Complex, Epitopes, Immune system, Immunology, HLA-DR, Humans, Surgery, HLA-DRB1 Chains
Published
1997

25. Indirect T-cell recognition in human allograft rejection

Author

Peter E. Fisher, E. Ho, Robert E. Michler, Adriana I. Colovai, Raffaello Cortesini, P. Cocciolo, Zhuoru Liu, Nicole Suciu-Foca, F. Gargano, M. A. Hardy, Elaine Reed, and Emily Rose

Subjects
Graft Rejection, Cellular immunity, Isoantigens, T cell, T-Lymphocytes, Pathogenesis, Immune system, Text mining, Medicine, Humans, Transplantation, Homologous, Alleles, Transplantation, business.industry, T lymphocyte, HLA-DR Antigens, Kidney Transplantation, Peptide Fragments, Liver Transplantation, medicine.anatomical_structure, Allograft rejection, Immunology, Heart Transplantation, Surgery, business, HLA-DRB1 Chains
Published
1997

26. Self-MHC restricted T cells specific for donor peptides infiltrate human grafts during rejection

Author

Paola Cinti, Paul L. Harris, Raffaello Cortesini, M. A. Hardy, Emily Rose, Adriana I. Colovai, Nicole Suciu-Foca, F. Gargano, Z. Liu, Donna Mancini, and R.E. Drusin

Subjects
Graft Rejection, Isoantigens, medicine.medical_treatment, T-Lymphocytes, Histocompatibility Testing, Biology, Major histocompatibility complex, Polymerase Chain Reaction, Isoantibodies, medicine, Humans, HLA-DR Antigen, Heart transplantation, Transplantation, Biopsy, Needle, T lymphocyte, HLA-DR Antigens, medicine.disease, Kidney Transplantation, Tissue Donors, Immunology, biology.protein, Heart Transplantation, Surgery, Infiltration (medical)
Published
1997

27. Suppression of allorecognition by use of synthetic peptides

Author

A I, Colovai, E, Renna-Molajoni, P L, Cocciolo, S, Tugulea, Z, Liu, P E, Harris, N, Suciu-Foca, and R, Cortesini

Subjects
Structure-Activity Relationship, T-Lymphocytes, Antigen-Presenting Cells, Humans, Amino Acid Sequence, HLA-DR Antigens, Lymphocyte Activation, Cells, Cultured, Peptide Fragments, Recombinant Proteins, Clone Cells, HLA-DR Serological Subtypes
Published
1996

28. Immunologic studies in primates undergoing concordant xenotransplantation as a bridge allotransplantation

Author

A S, Shah, S, Itescu, D P, O'Hair, S, Tugulea, P A, Kwiatkowski, Z, Liu, J L, Platt, E A, Rose, N, Suciu-Foca, and R E, Michler

Subjects
B-Lymphocytes, T-Lymphocytes, Transplantation, Heterologous, Histocompatibility Antigens Class II, Antibodies, Heterophile, Methylprednisolone, Macaca fascicularis, Lymphocyte Transfusion, Azathioprine, Cyclosporine, Animals, Heart Transplantation, Transplantation, Homologous, Immunosuppressive Agents, Papio
Published
1996

29. Importance of cell-mediated immune responses in rejection of concordant heart xenografts in primates

Author

A S, Shah, S, Itescu, D P, O'Hair, S, Tugulea, P A, Kwiatkowski, Z, Liu, J L, Platt, E A, Rose, N, Suciu-Foca, and R E, Michler

Subjects
Cytotoxicity, Immunologic, Graft Rejection, B-Lymphocytes, Immunity, Cellular, Macaca fascicularis, T-Lymphocytes, Histocompatibility Antigens Class I, Transplantation, Heterologous, Histocompatibility Antigens Class II, Animals, Heart Transplantation, Antibodies, Heterophile, Papio
Published
1996

30. Influence of HLA matching on kidney allograft survival

Author

N, Suciu-Foca, D J, Cohen, A I, Benvenisty, J A, Benstein, E F, Reed, E, Ho, and M A, Hardy

Subjects
Reoperation, Survival Rate, Actuarial Analysis, Histocompatibility Testing, Graft Survival, Humans, Transplantation, Homologous, Cyclosporins, Kidney Transplantation, Immunosuppressive Agents, Tissue Donors, Retrospective Studies
Published
1996

31. Role of indirect allorecognition in chronic rejection of human allografts

Author

N, Suciu-Foca, Z, Liu, A I, Colovai, S, Tugulea, E F, Reed, D, Mancini, D J, Cohen, A I, Benvenisty, J A, Benstein, M A, Hardy, L L, Schulman, and E A, Rose

Subjects
Graft Rejection, Isoantibodies, Biopsy, Histocompatibility Testing, T-Lymphocytes, Acute Disease, Antibody Formation, Chronic Disease, Heart Transplantation, Humans, Transplantation, Homologous, Lung Transplantation
Published
1996

33. Indirect recognition of native HLA alloantigens and B-cell help

Author

N, Suciu-Foca, Z, Liu, P E, Harris, E F, Reed, D J, Cohen, J A, Benstein, A I, Benvenisty, D, Mancini, R E, Michler, and E A, Rose

Subjects
B-Lymphocytes, Isoantigens, Receptors, Antigen, T-Cell, alpha-beta, T-Lymphocytes, Gene Expression, HLA-DR Antigens, Spodoptera, Transfection, Polymerase Chain Reaction, Recombinant Proteins, Cell Line, Epitopes, HLA-DR4 Antigen, Animals, Humans, RNA, Messenger
Published
1995

34. Mycophenolate mofetil reduces anti-HLA antibody production and cellular rejection in heart transplant recipients

Author

Silviu Itescu, M. Schuster, Nicole Suciu-Foca, Donna Mancini, Ranjit John, Katherine Lietz, E. Burke, J Ankersmit, and Niloo M. Edwards

Subjects
Graft Rejection, Male, Reoperation, Cellular immunity, Time Factors, medicine.medical_treatment, Mycophenolate, Mycophenolic acid, Immune system, Azathioprine, Humans, Medicine, Retrospective Studies, Transplantation, biology, business.industry, Immunosuppression, Middle Aged, Mycophenolic Acid, Humoral immunity, Immunology, Cyclosporine, biology.protein, Heart Transplantation, Drug Therapy, Combination, Female, Surgery, Antibody, business, Immunosuppressive Agents, Follow-Up Studies, medicine.drug
Published
2002
Full Text
View/download PDF

35. Effect of anti-HLA antibodies on the long-term survival of heart and kidney allografts

Author

M L, Barr, D J, Cohen, A I, Benvenisty, M, Hardy, K, Reemtsma, E A, Rose, C C, Marboe, V, D'Agati, N, Suciu-Foca, and E, Reed

Subjects
Graft Rejection, HLA-D Antigens, Arteriosclerosis, Graft Survival, Histocompatibility Antigens Class I, Kidney Transplantation, Antibodies, Anti-Idiotypic, HLA Antigens, Antibody Formation, Heart Transplantation, Humans, Transplantation, Homologous, Biomarkers, Retrospective Studies
Abstract

Study of anti-HLA antibodies in a population of 238 primary renal and 199 primary heart allograft recipients showed significant association between development of anti-HLA antibodies and that of chronic allograft rejection. The 5-year renal allograft survival was 70% in recipients without antibodies and 53% in recipients who developed anti-HLA alloantibodies during the first year following transplantation. Heart allograft survival at 5 years was 91% in patients without and 78% in patients with antibodies during the first 12 months posttransplantation. Development of antibodies is associated with acute rejection episodes and probably with the release of soluble HLA antigens.

Published
1993

37. Increased risk for cardiac allograft rejection in recipients with HLA-B8, DR3 type

Author

Katherine Lietz, Silviu Itescu, Elizabeth Burke, Niloo M. Edwards, Donna Mancini, Nicole Suciu-Foca, Roy M. John, Michael D. Schuster, and Alfred Kocher

Subjects
Adult, Graft Rejection, Risk, Transplantation, Cardiac allograft, business.industry, HLA-B8 Antigen, Histocompatibility, HLA-DR3 Antigen, Increased risk, Immunology, Heart Transplantation, Humans, Transplantation, Homologous, Medicine, Surgery, Risk factor, business
Published
2001
Full Text
View/download PDF

38. Effect of anti-HLA and anti-idiotypic antibodies on the long-term survival of heart and kidney allografts

Author

E, Reed, D J, Cohen, M L, Barr, E, Ho, C C, Marboe, E A, Rose, M, Hardy, and N, Suciu-Foca

Subjects
Graft Rejection, Histocompatibility Testing, Graft Survival, Kidney Transplantation, Antibodies, Anti-Idiotypic, Survival Rate, Postoperative Complications, Actuarial Analysis, HLA Antigens, Isoantibodies, Chronic Disease, Cyclosporine, Heart Transplantation, Humans, Follow-Up Studies
Abstract

Long-term survival of heart and kidney allografts is threatened by the development of chronic rejection. Analysis of the relationship between reversible acute rejection episodes and actuarial survival at 5 years showed an inverse correlation suggesting that early cellular events may trigger antibody-mediated chronic rejection. In both heart and kidney allograft recipients producing anti-HLA antibodies we found a significant decrease in the 5-year graft survival rate. However, there was heterogeneity among anti-HLA antibody producers with respect to the development of anti-idiotypic antibodies. The actuarial 5-year graft survival was significantly higher in patients with Ab2 compared to patients without.

Published
1992

39. Effect of recipient gender and race on heart and kidney allograft survival

Author

E, Reed, D J, Cohen, M L, Barr, E, Ho, K, Reemtsma, E A, Rose, M, Hardy, and N, Suciu-Foca

Subjects
Graft Rejection, Histocompatibility Testing, Graft Survival, Age Factors, Black People, Kidney Transplantation, White People, Survival Rate, Postoperative Complications, Sex Factors, Actuarial Analysis, HLA Antigens, Cadaver, Heart Transplantation, Humans, Follow-Up Studies
Abstract

Study of long-term survival of heart allografts shows that AA males and females have lower graft survival rates than those observed in NAC recipients. Primary kidney allografts in AA males, but not females, also display lower 5-year survival rates compared to those observed in the corresponding populations of NAC. Comparison of graft survival in the overall population of male and female recipients of kidney allografts shows that females have higher graft survival rates, probably as a result of better HLA matching. The level of alloantibody activity in posttransplantation sera is similar in the two populations, suggesting that factors other than HLA mismatching may contribute to the higher degree of graft failure in AA recipients.

Published
1992

40. Soluble HLA and anti-idiotypic antibodies in transplantation: modulation of anti-HLA antibodies by soluble HLA antigens from the graft and anti-idiotypic antibodies in renal and cardiac allograft recipients

Author

N, Suciu-Foca, E, Ho, D W, King, Y P, Yu, S, Yu-Kai, E, Reed, D, Cohen, J M, Brensilver, R, McCabe, and E, Rose

Subjects
Graft Rejection, Isoantigens, Solubility, HLA Antigens, Graft Survival, Heart Transplantation, Humans, Transplantation, Homologous, Antigen-Antibody Complex, Kidney Transplantation, Antibodies, Anti-Idiotypic, Follow-Up Studies
Published
1991

42. The effect of antiidiotypic antibodies in the rat: II. Correlation of in vitro blocking activity and immunopathology of cardiac allograft survival

Author

T, Wasfie, E, Reed, C, Marboe, N, Suciu-Foca, and M A, Hardy

Subjects
Cytotoxicity, Immunologic, Graft Survival, Immunization, Passive, Skin Transplantation, Antibodies, Anti-Idiotypic, Rats, Rats, Inbred ACI, Immunoglobulin M, Rats, Inbred Lew, Immunoglobulin G, Animals, Heart Transplantation, Transplantation, Homologous, Lymphocyte Culture Test, Mixed
Published
1991

43. Mechanism of liver allograft rejection: indirect allorecognition

Author

L Elia, E Renna-Molajoni, Paola Cinti, Nicole Suciu-Foca, Raffaello Cortesini, P. Cocciolo, A.M Orlandini, Eric K. Ho, and J Molajoni

Subjects
CD4-Positive T-Lymphocytes, Graft Rejection, B-Lymphocytes, Isoantigens, Transplantation, Mechanism (biology), CD8-Positive T-Lymphocytes, Biology, T-Lymphocytes, Regulatory, Liver Transplantation, Immune tolerance, Immune system, Isoantibodies, Allograft rejection, Acute Disease, Immunology, Humans, Transplantation, Homologous, Surgery, Allorecognition, Cells, Cultured, Follow-Up Studies
Published
1999
Full Text
View/download PDF

44. Generation and characterization of xenospecific human suppressor T cells

Author

Pasquale Berloco, Adriana I. Colovai, Rodica Ciubotariu, Nicole Suciu-Foca, Raffaello Cortesini, and Zhuoru Liu

Subjects
CD4-Positive T-Lymphocytes, Cellular immunity, Swine, Antigen presentation, Antigen-Presenting Cells, Biology, Lymphocyte Activation, T-Lymphocytes, Regulatory, Animal origin, Cell Line, Immunophenotyping, law.invention, Immune tolerance, Antigens, CD, law, Antigens, Heterophile, Animals, Humans, Transplantation, Cell growth, Histocompatibility Antigens Class II, T-Lymphocytes, Helper-Inducer, T lymphocyte, Flow Cytometry, In vitro, Cell biology, Immunology, Swine, Miniature, Suppressor, Surgery
Published
1999
Full Text
View/download PDF

46. Specific immunosuppression of the indirect recognition pathway

Author

Nicole Suciu-Foca and Raffaello Cortesini

Subjects
CD4-Positive T-Lymphocytes, Graft Rejection, Isoantigens, T-Lymphocytes, medicine.medical_treatment, Receptors, Antigen, T-Cell, Biology, Epitope, Cell Line, Epitopes, Immune system, Text mining, medicine, Transplantation, Homologous, Humans, Immunosuppression Therapy, HLA-D Antigens, Transplantation, business.industry, Immunosuppression, T lymphocyte, Immunotherapy, Peptide Fragments, Immunology, Surgery, business
Published
1998
Full Text
View/download PDF

47. Indirect allorecognition of donor HLA-DR peptides in chronic rejection of heart allografts

Author

Silviu Itescu, Rodica Ciubotariu, Nicole Suciu-Foca, Eric A. Rose, and Raffaello Cortesini

Subjects
Graft Rejection, Isoantigens, Transplantation, business.industry, Mechanism (biology), HLA-DR Antigens, Peptide Fragments, Antigen, Chronic Disease, Immunology, HLA-DR, Heart Transplantation, Humans, Transplantation, Homologous, Medicine, Surgery, business, Allorecognition
Published
1998
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results