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48 results on '"Cuervas‐Mons, V"'

27. Risk Factors for Clostridioides Difficile Diarrhea In Solid Organ Transplantation Recipients.

Author

Ortiz-Balbuena J, Royuela A, Calderón-Parra J, Martínez-Ruiz R, Asensio-Vegas Á, Múñez E, Valencia-Alijo Á, Gutiérrez-Rojas Á, Ussetti P, Cuervas-Mons V, Segovia-Cubero J, Portolés-Pérez J, and Ramos-Martínez A

Subjects
Adult, Aged, Case-Control Studies, Clostridioides, Diarrhea, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors, Transplant Recipients, Clostridioides difficile, Clostridium Infections diagnosis, Clostridium Infections epidemiology, Organ Transplantation adverse effects
Abstract

Background: There is limited knowledge about risk factors for Clostridioides difficile infection (CDI) and recurrent CDI in solid organ transplant (SOT) recipients., Methods: A case-control study of CDI in SOT recipients compared with controls (SOT recipients who did not present CDI)., Results: Sixty-seven patients from 1089 SOT recipients (6.2%) suffered at least one episode of CDI. The mean age was 55 ± 12 years and 20 cases (69%) were men. The accumulated incidence was 8% in liver transplantation, 6.2% in lung transplantation, 5.4% in heart transplantation, and 4.7% in kidney transplantation. Twenty-nine cases (43.3%) were diagnosed during the first 3 months after SOT. Forty-one cases (61.2%) were hospital acquired. Thirty-one patients with CDI presented with mild-moderate infection (46.3%), 30 patients with severe infection (44.8%), and 6 patients with severe-complicated disease (9%). Independent variables found to be related with CDI were hospitalization in the previous 3 months (odds ratio: 2.99; [95% confidence interval 1.21-7.37]) and the use of quinolones in the previous month (odds ratio: 3.71 [95% confidence interval 1.16-11.8]). Eleven patients (16.4%) had at least one recurrence of CDI. Previous treatment with amoxicillin-clavulanate, severe-complicated index episode, and high serum creatinine were associated with recurrent CDI in the univariant analysis CONCLUSIONS: Liver transplant recipients presented the highest incidence of CDI among SOT recipients. Risk factors for CDI were hospitalization in the previous 3 months and the use of quinolones in the previous month., (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.)

Published
2021
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28. Autoimmune Extrahepatic Disorders in Patients With Autoimmune Liver Disease.

Author

Contreras GV, Marugan MT, and Cuervas-Mons V

Subjects
Adult, Female, Humans, Retrospective Studies, Severity of Illness Index, Cholangitis, Sclerosing complications, Cholangitis, Sclerosing surgery, End Stage Liver Disease, Hepatitis, Autoimmune complications, Hepatitis, Autoimmune diagnosis, Inflammatory Bowel Diseases
Abstract

Background: Autoimmune liver diseases (ALDs) (primary biliary cholangitis, primary sclerosing cholangitis [PSC], autoimmune hepatitis [AIH]) can present extrahepatic autoimmune manifestations, the most frequent being inflammatory bowel disease (IBD), autoimmune thyroid disease, and Sjögren syndrome (SS)., Methods: Retrospective study of patients who have undergone liver transplant (LT) with post-LT follow-up of at least 2 years. Descriptive analysis of clinical variables and overall and graft survival., Results: ALD was an infrequent indication for LT (68 of 835, 8%), 39 primary biliary cholangitis, 17 AIH, and 12 PSC; 56 were women. The mean (standard deviation [SD]) pre-LT Model for End-Stage Liver Disease score was 17 (5.4). The mean (SD) age of LT recipients at LT was 40 (21) years. A total of 27 patients presented extrahepatic autoimmune diseases. The most frequent was IBD in 7 patients, preferentially in patients with PSC (10/12), followed by Sjögren syndrome and autoimmune thyroid disease. IBD was present in 12 patients: 8 ulcerative colitis (6 PSC and 2 AIH overlap syndrome), 2 Crohn disease both PSC, and another 2 PSC and IBD without conclusive diagnosis (neither for ulcerative colitis nor Crohn disease). Five presented IBD de novo post-LT; the other 7 debuted before LT. In 3 of these 7 patients with pre-LT IBD, the disease went into remission after LT. Colectomy was necessary in 3 patients. No statistically significant findings were found in the survival analysis., Conclusions: ALD is an infrequent reason for LT. Extrahepatic autoimmune diseases are associated in these patients, with IBD being the most frequent. IBD presents a torpid course but does not impact overall survival., (Copyright © 2021 Elsevier Inc. All rights reserved.)

Published
2021
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32. Is the use of University of Wisconsin solution with prolonged ischemia time an option in clinical liver transplantation?

Author

Nuño J, Cuervas-Mons V, Vicente E, Turrión V, Pereira F, Mora NP, Barrios C, Millán I, and Ardaiz J

Subjects
Adenosine, Adult, Allopurinol, Female, Glutathione, Humans, Insulin, Liver Transplantation mortality, Liver Transplantation physiology, Male, Morbidity, Raffinose, Retrospective Studies, Ischemia, Liver blood supply, Liver Transplantation methods, Organ Preservation methods, Organ Preservation Solutions, Postoperative Complications epidemiology
Published
1995

33. Prolonged graft cold ischemia: a risk factor for early bacterial and fungal infection in liver transplant recipients.

Author

Nuño J, Cuervas-Mons V, Vicente E, Turrión V, Pereira F, Mora NP, Barrios C, Millán I, and Ardaiz J

Subjects
Adult, Analysis of Variance, Chi-Square Distribution, Female, Humans, Male, Postoperative Complications epidemiology, Regression Analysis, Retrospective Studies, Risk Factors, Bacterial Infections epidemiology, Ischemia, Liver blood supply, Liver Transplantation, Mycoses epidemiology, Organ Preservation, Postoperative Complications microbiology
Published
1995

34. Renal failure after liver transplantation: analysis of risk factors in 139 liver transplant recipients.

Author

Nuño J, Cuervas-Mons V, Vicente E, Turrión V, Pereira F, Mora NP, Barrios C, Millán I, and Ardaiz J

Subjects
Creatinine blood, Follow-Up Studies, Humans, Medical Records, Regression Analysis, Renal Insufficiency diagnosis, Retrospective Studies, Risk Factors, Time Factors, Liver Transplantation, Postoperative Complications epidemiology, Renal Insufficiency epidemiology
Published
1995

35. Is liver transplantation an emergency or an elective surgical procedure? Analysis of risk factors related to early mortality in 139 liver transplant recipients.

Author

Nuño J, Cuervas-Mons V, Vicente E, Turrión V, Pereira F, Mora NP, Barrios C, Millán I, and Ardaiz J

Subjects
Adenosine, Allopurinol, Female, Glutathione, Humans, Hypertonic Solutions, Insulin, Ischemia, Liver blood supply, Liver Transplantation methods, Male, Organ Preservation, Postoperative Complications mortality, Probability, Prognosis, Raffinose, Renal Insufficiency epidemiology, Renal Insufficiency mortality, Retrospective Studies, Risk Factors, Time Factors, Elective Surgical Procedures, Emergencies, Liver Transplantation mortality, Organ Preservation Solutions, Postoperative Complications epidemiology
Published
1995

36. Prospective study of the incidence, timing, significance, risk factors, and outcome of cytomegalovirus infection in liver transplant patients with double-drug immunosuppression and no prophylactic antiviral therapy.

Author

Sanchez-Turrión V, Cuervas-Mons V, Portero F, Barrios C, Garrido A, and Albillos A

Subjects
Adult, Antibodies, Viral blood, Cytomegalovirus isolation & purification, Cytomegalovirus Infections epidemiology, Cytomegalovirus Infections etiology, Drug Therapy, Combination, Ganciclovir therapeutic use, Graft Rejection, Humans, Immunosuppression Therapy methods, Incidence, Prognosis, Prospective Studies, Risk Factors, Time Factors, Treatment Outcome, Cyclosporine therapeutic use, Cytomegalovirus Infections physiopathology, Liver Transplantation immunology, Prednisone therapeutic use
Published
1993

37. Incidence and risk factors of early acute renal failure in liver transplant patients.

Author

Pascual E, Gómez-Arnau J, Pensado A, de la Quintana B, Carrera A, Arribas MJ, García-Guiral M, and Cuervas-Mons V

Subjects
Acute Kidney Injury etiology, Analysis of Variance, Cyclosporine therapeutic use, Dopamine therapeutic use, Humans, Incidence, Mannitol therapeutic use, Prednisone therapeutic use, Retrospective Studies, Risk Factors, Time Factors, Acute Kidney Injury epidemiology, Liver Transplantation immunology, Liver Transplantation methods, Postoperative Complications epidemiology
Published
1993

43. Analysis of cytomegalovirus reactivation after liver transplantation in cytomegalovirus immunoglobulin G antibody seropositive patients prior to transplantation.

Author

Cuervas-Mons V, Garrido A, Barrios C, Portero F, de la Loma A, Albillos A, Ardaiz J, Turrión VS, Mora NP, and Herrera J

Subjects
Adrenal Cortex Hormones therapeutic use, Adult, Antibodies, Monoclonal therapeutic use, Azathioprine therapeutic use, Blood Transfusion, Cyclosporins therapeutic use, Female, Follow-Up Studies, Graft Rejection, Humans, Immunosuppression Therapy, Male, Muromonab-CD3, Prospective Studies, Serologic Tests, Cytomegalovirus Infections immunology, Immunoglobulin G analysis, Liver Transplantation immunology
Published
1990

47. Monitoring of the rejection of intrasplenic hepatocyte allografts and xenografts in the rat using technetium 99m-imidoacetic acid scanning.

Author

Cuervas-Mons V, Cantón T, Escandón J, Nieto J, Ramos J, Menéndez J, Ortiz J, Castillo-Olivares JL, and Segovia JM

Subjects
Animals, Dogs, Liver cytology, Liver diagnostic imaging, Radionuclide Imaging, Rats, Spleen, Transplantation, Heterologous, Graft Rejection, Imino Acids, Liver Transplantation, Organometallic Compounds, Organotechnetium Compounds, Technetium
Published
1987

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