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4 results on '"Jake Shortt"'

1. Red cell transfusions: Is less always best?

Author

Erica M. Wood, Zoe McQuilten, Allison Mo, Simon J. Stanworth, and Jake Shortt

Subjects
medicine.medical_specialty, Standard of care, Heart Diseases, Immunology, Pilot Projects, Oxygen Consumption, Outcome Assessment, Health Care, Outpatients, medicine, Humans, Immunology and Allergy, Practice Patterns, Physicians', Intensive care medicine, Exercise, Diagnosis-Related Groups, Randomized Controlled Trials as Topic, Evidence-Based Medicine, Red Cell, business.industry, Hematopoietic Stem Cell Transplantation, Standard of Care, Hematology, Patient Outcome Assessment, Hematologic Neoplasms, Practice Guidelines as Topic, Therapeutic Equipoise, Erythrocyte Transfusion, business
Published
2021
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2. N-Acetylcysteine for thrombotic thrombocytopenic purpura: is a von Willebrand factor-inhibitory dose feasible in vivo?

Author

Erica M. Wood, Stephen Opat, and Jake Shortt

Subjects
Purpura, Thrombotic Thrombocytopenic, biology, business.industry, Immunology, Thrombotic thrombocytopenic purpura, Hematology, Pharmacology, Inhibitory postsynaptic potential, medicine.disease, Acetylcysteine, Von Willebrand factor, In vivo, biology.protein, Humans, Immunology and Allergy, Medicine, Female, business, medicine.drug
Published
2014
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3. Assessment of the urgency and deferability of transfusion to inform emergency blood planning and triage: the Bloodhound prospective audit of red blood cell use

Author

Damien Jolley, Erica M. Wood, Mark N. Polizzotto, Neil Waters, Jake Shortt, Mary Comande, Marija Borosak, Martine Moran, and Alexandra Devine

Subjects
medicine.medical_specialty, Hematology, business.industry, Prospective audit, Immunology, MEDLINE, Economic shortage, Triage, Confidence interval, Internal medicine, medicine, Immunology and Allergy, Humans, Blood Transfusion, Elective surgery, Emergencies, Intensive care medicine, business, Erythrocyte Transfusion
Abstract

BACKGROUND: Careful planning is essential to ensure blood availability during shortages. Triaging supply is one proposed strategy; however, few data concerning the urgency of transfusion are available to inform planning. This study sought to determine the proportion of red blood cells (RBCs) used for clinically urgent indications. STUDY DESIGN AND METHODS: A total of 5132 RBC units were randomly selected at point of production and distributed into general statewide inventory over a 9-month period. These selected units carried case report forms, for completion at the point of hospital issue for transfusion. Completed forms were returned to the blood service for collation and analysis, capturing information on indication and clinical urgency of supply, including use for potentially deferrable elective surgery. RESULTS: Data from 5052 RBC units indicated that 95.6% were transfused. Approximately one-third of transfused units were used to support surgery, one-third for hematology/oncology, and one-third for other medical and miscellaneous indications. Where used for surgery, 25.7% (95% confidence interval [CI], 23.4%-28.0%) were for elective procedures, although urgency of surgery was unknown in 17.1% (95% CI, 15.2%-19.2%) of cases. Supply for nonurgent medical indications and elective surgery only accounted for 9.8% (95% CI, 9.0%-10.6%) of use, with 53.4% (95% CI, 52.0%-54.8%) of RBCs required within 24 hours. CONCLUSIONS: The majority of RBCs are transfused with a high degree of clinical urgency, with only a minor proportion required to support elective surgery.

Published
2009

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