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1. Clock-controlled rhythmic transcription: is the clock enough and how does it work?

Author

Beytebiere JR, Greenwell BJ, Sahasrabudhe A, and Menet JS

Subjects
Animals, Gene Expression Regulation, Humans, Promoter Regions, Genetic, Transcription Factors metabolism, Circadian Clocks, Transcription, Genetic
Abstract

Circadian clocks regulate the rhythmic expression of thousands of genes underlying the daily oscillations of biological functions. Here, we discuss recent findings showing that circadian clock rhythmic transcriptional outputs rely on additional mechanisms than just clock gene DNA binding, which may ultimately contribute to the plasticity of circadian transcriptional programs.

Published
2019
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