111 results on '"Water, A."'
Search Results
2. P06-09: Computational modelling of integrated stress response and oxidative stress response for cellular adversity predictions
3. S24-02: Gene network approaches predictive of adverse outcomes
4. P22-02: The Renal Proximal Tubule TXG-MAPr: Safety Assessment Based On Quantitative Gene Network Analysis
5. CEC01-04: Toxicogenomics data and analysis workflows
6. P16-18: Human-induced pluripotent stem cell reporters for high-content screening of stress response activation identifying target organ-specific toxicities
7. P01-06 Development of a network of adverse outcome pathways for chemically induced oxidative stress leading to (non-)genotoxic carcinogenesis
8. P20-09 Which scope of NAM testing is sufficient for hazard characterisation? – An investigation based on transcriptomics data
9. P22-12 Benchmark dose response modelling of gene co-expression networks in hepatocytes exposed to known inducers of liver steatosis, cholestasis and necrosis
10. S-25-02 Gene co-expression network analysis of toxicogenomic data linked to histopathology provides quantitative mode-of-action assessment and prediction of drug-induced organ toxicity
11. P14-16 Application of various human in vitro systems for the confirmation of cellular targets and the molecular toxicity of glutathione conjugates of Trichloroethylene
12. LP-12 Deciphering the quantitative relationship between chemical kinetics and Nrf2 pathway dynamics
13. P06-23 Integration of metabolomics and transcriptomics for improved mechanism-based hazard characterization of drug-induced liver injury
14. S27-03 Population variability of toxicodynamics driving adverse responses
15. S-25-02 Gene co-expression network analysis of toxicogenomic data linked to histopathology provides quantitative mode-of-action assessment and prediction of drug-induced organ toxicity
16. P22-12 Benchmark dose response modelling of gene co-expression networks in hepatocytes exposed to known inducers of liver steatosis, cholestasis and necrosis
17. P20-09 Which scope of NAM testing is sufficient for hazard characterisation? – An investigation based on transcriptomics data
18. P01-06 Development of a network of adverse outcome pathways for chemically induced oxidative stress leading to (non-)genotoxic carcinogenesis
19. P14-16 Application of various human in vitro systems for the confirmation of cellular targets and the molecular toxicity of glutathione conjugates of Trichloroethylene
20. LP-12 Deciphering the quantitative relationship between chemical kinetics and Nrf2 pathway dynamics
21. Dynamic imaging of stress response pathway activation for quantitative systems liver toxicity approaches
22. Quantitative Bayesian Network Analyses of Mitochondrial Toxicity
23. Dissecting lineage specific oxidative stress response dynamics using high content imaging of the hiPSC HMOX1 fluorescent reporter line
24. Data-driven computational modeling of the DNA damage response and liver toxicity
25. Transcriptomic profiling of the inter-individual variability of chemical-induced cellular stress response activation in primary human hepatocytes
26. Validation of the ToxProfiler reporter assay for toxicological profiling and determination of the underlying mode of action
27. WGCNA in vivo rat liver co-expressed modules to derive human in vitro reporters associated with pathology
28. Validation of the ToxProfiler reporter assay for toxicological profiling and determination of the underlying mode of action
29. Dynamic imaging of stress response pathway activation for quantitative systems liver toxicity approaches
30. Data-driven computational modeling of the DNA damage response and liver toxicity
31. Quantitative Bayesian Network Analyses of Mitochondrial Toxicity
32. Dissecting lineage specific oxidative stress response dynamics using high content imaging of the hiPSC HMOX1 fluorescent reporter line
33. WGCNA in vivo rat liver co-expressed modules to derive human in vitro reporters associated with pathology
34. Gene expression markers in the zebrafish embryo reflect a hepatotoxic response in animal models and humans
35. Development and validation of computational models for predicting oxidative stress responses using comprehensive series of drug-like compounds
36. Single cell imaging for quantitative systems toxicology of hepatoxicity
37. Mitochondrial toxicity and oxidative stress: Defining the tipping point between adaptive and adverse effects for consumer safety risk assessment
38. Development and validation of computational models for predicting oxidative stress responses using comprehensive series of drug-like compounds
39. High throughput adaptive stress response pathway activation to support read across of valproic acid analogue-induced liver steatosis
40. Unravelling essential key events in mitochondrial adverse outcome pathways
41. Single cell imaging for quantitative systems toxicology of hepatoxicity
42. Quantitative assessment of mitochondrial toxicity and downstream cellular perturbations in Adverse Outcome Pathways
43. Use of new approach methods to support chemical read-across: the EU-ToxRisk experience
44. Imaging and computational modelling to unravel the dynamics of the oxidative stress pathway upon repeated perturbation
45. Identification of oxidative stress potential in phenolic compounds and their link to liver injury
46. Mitochondrial toxicity and oxidative stress: Defining the tipping point between adaptive and adverse effects for consumer safety risk assessment
47. Identification of oxidative stress potential in phenolic compounds and their link to liver injury
48. Imaging and computational modelling to unravel the dynamics of the oxidative stress pathway upon repeated perturbation
49. High throughput adaptive stress response pathway activation to support read across of valproic acid analogue-induced liver steatosis
50. Use of new approach methods to support chemical read-across: the EU-ToxRisk experience
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