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Your search keyword '"Dominik Steiner"' showing total 2 results
Start Over Author "Dominik Steiner" Journal tissue engineering part a
2 results on '"Dominik Steiner"'

1. Human Umbilical Vein Endothelial Cell Support Bone Formation of Adipose-Derived Stem Cell-Loaded and 3D-Printed Osteogenic Matrices in the Arteriovenous Loop Model

Author

Andrea Meyer-Lindenberg, Sophie Winkler, Hilkea Mutschall, Carolin Körner, Raymund E. Horch, Jonas Biggemann, Tobias Fey, Dominik Steiner, Andreas Arkudas, Volker Weisbach, and Peter Greil

Subjects
3d printed, Angiogenesis, 0206 medical engineering, Cell, Biomedical Engineering, Adipose tissue, Bioengineering, 02 engineering and technology, Biochemistry, Bone tissue engineering, Biomaterials, 03 medical and health sciences, Osteogenesis, Human Umbilical Vein Endothelial Cells, medicine, Animals, Humans, Bone formation, Cells, Cultured, 030304 developmental biology, 0303 health sciences, Tissue Engineering, Tissue Scaffolds, Chemistry, Stem Cells, Regeneration (biology), Cell Differentiation, Mesenchymal Stem Cells, 020601 biomedical engineering, Rats, Cell biology, medicine.anatomical_structure, Adipose Tissue, Printing, Three-Dimensional, Human umbilical vein endothelial cell
Abstract

Introduction: For the regeneration of large volume tissue defects, the interaction between angiogenesis and osteogenesis is a crucial prerequisite. The surgically induced angiogenesis by means of a...

Published
2021
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2. Encapsulation of Mesenchymal Stem Cells Improves Vascularization of Alginate-Based Scaffolds

Author

Lara F. Lingens, Raymund E. Horch, Laura Fischer, Christian Weis, Andreas Arkudas, Tobias Fey, Dominik Steiner, Peter Greil, Aldo R. Boccaccini, Justus P. Beier, Katrin Köhn, and Rainer Detsch

Subjects
Male, 0301 basic medicine, Scaffold, Alginates, Angiogenesis, Biomedical Engineering, Neovascularization, Physiologic, Bioengineering, 02 engineering and technology, Biochemistry, Biomaterials, 03 medical and health sciences, Tissue engineering, Animals, Tissue Scaffolds, Chemistry, fungi, Mesenchymal stem cell, food and beverages, Mesenchymal Stem Cells, Cells, Immobilized, 021001 nanoscience & nanotechnology, Rats, Encapsulation (networking), Cell biology, 030104 developmental biology, Rats, Inbred Lew, 0210 nano-technology
Abstract

Vascularization of bioartificial tissues can be significantly enhanced by the generation of an arteriovenous (AV) loop. Besides the surgical vascularization, the choice of the scaffold and the applied cells are indispensable cofactors. The combination of alginate dialdehyde and gelatin (ADA-GEL) and mesenchymal stem cells (MSCs) is a promising approach with regard to biocompatibility, biodegradation, as well as de novo tissue formation. In this study, we targeted the investigation of the vascularization of ADA-GEL with and in the absence of encapsulated MSCs in the AV loop model. A Teflon chamber filled with ADA-GEL microcapsules was placed in the groin of Lewis rats and an AV loop was placed into the chamber. Group A encompassed the ADA-GEL without MSCs, whereas group B contained 2 × 10

Published
2018
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