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MUKADA, T., KASHIWAGURA, J., ITASAKA, K., MIYAZAKI, S., HIRAKAWA, H., SASAKI, Y., ANDOH, S., IGURA, H. and MINETA, T. Giant Hyperplasiogenous Polyp of the Stomach Simulating Malignant Polyp. Tohoku J. exp. Med., 1984, 142 (2), 125-130 - A surgical case of giant hyperplasiogenous polyp of the stomach with unusual radiological and pathological findings is presented. Radiological and endoscopical examinations revealed characteristic papillary (villous) features simulating either true adenoma or malignant polyp of the antrum. Complete serial sections from the resected stomach disclosed no malignant area anywhere in and out of the polyp. The pathomorphological nature and radiological characteristics of this rare lesion are discussed.

MUKADA, T., ITASAKA, K., MIYAZAKI, S., HIRAKAWA, H., KASHIWAGURA, J., SASAKI, Y., ANDOH, S., SHINZAWA, A. and SENDOH, F. Pulmonary Hypertension Associated with Liver Cirrhosis and Hepatitis-B Antigenemia. Tohoku J. exp. Med., 1983, 139 (1), 83-90 - An autopsy case of pulmonary hypertension in a 29-year-old Japanese female with macronodular, posthepatitic liver cirrhosis and hepatitis-B antigenemia was presented. No recognizable known cardiopulmonary disease or portal thrombosis was obtained. Hepatitis-B antigen was demonstrated in the cirrhotic hepatocytes by a specific peroxidase antiperoxidase method. Characteristic pulmonary arterial changes including plexiform lesions with varying developmental stages were widely observed throughout the lungs. Complication of these two distinct disease processes seems to be rarely encountered in the literature. Discussion was focused on the possible interrelationship between the liver cirrhosis with hepatitis-B antigenemia and pulmonary hypertension. Proposed were presumptive underlying humoral, particularly immunological, abnormalities common to these diseases rather than mere incidental complications.