1. Middle lobe syndrome as the pulmonary manifestation of primary Sjögren's syndrome
- Author
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Horng-An Chen, De-Feng Huang, Chun-Hsiung Chen, Wei-Kang Kwang, Shinn-Liang Lai, and Juhn-Cherng Liu
- Subjects
Systemic disease ,Pathology ,medicine.medical_specialty ,Eye disease ,Prednisolone ,Atelectasis ,Lymphocytic Infiltrate ,Recurrence ,Middle Lobe Syndrome ,medicine ,Humans ,Glucocorticoids ,Lung ,Autoimmune disease ,Bronchiectasis ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Radiography ,Sjogren's Syndrome ,Treatment Outcome ,Bronchiolitis ,Female ,business - Abstract
Middle lobe syndrome - recurrent atelectasis and/or bronchiectasis involving the right middle lobe and/or lingula - has, up to now, not been reported as the pulmonary manifestation of primary Sjogren's syndrome. We describe a patient in whom lymphocytic bronchiolitis in the atelectatic lobes was proved histologically from two separate transbronchial biopsies. The atelectasis responded well to glucocorticoid treatment, suggesting that the peribronchiolar lymphocytic infiltrates may have played an important role in the development of middle lobe syndrome in this patient.
- Published
- 2005