1. Modified Head and Neck Swallow Scale: Using <scp>EORTC‐QLQ‐H</scp> & <scp>N35</scp> to Predict Overall Survival
- Author
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Yash Patil, Stephen Romeo, Rebecca J. Howell, Liang Niu, Alice Tang, Siddarth Khosla, Douglas von Allmen, Meredith E. Tabangin, Keith A. Casper, Jessica Masch, Mekibib Altaye, Chad A. Zender, Keith M. Wilson, and Vinita Takiar
- Subjects
Male ,medicine.medical_specialty ,Risk Assessment ,Severity of Illness Index ,Swallowing ,Quality of life ,Predictive Value of Tests ,Surveys and Questionnaires ,Internal medicine ,medicine ,Humans ,Prospective Studies ,Aged ,Neoplasm Staging ,Retrospective Studies ,business.industry ,Proportional hazards model ,Head and neck cancer ,Hazard ratio ,Retrospective cohort study ,Middle Aged ,medicine.disease ,Dysphagia ,Otorhinolaryngology ,Head and Neck Neoplasms ,Quality of Life ,Feasibility Studies ,Female ,medicine.symptom ,Deglutition Disorders ,business ,Cohort study - Abstract
OBJECTIVES/HYPOTHESIS Dysphagia is a treatment-related complication of head and neck cancer (HNCA). We demonstrate the predictive value of a modified head and neck swallow scale (m-HNSW) adapted from the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35 (EORTC-QLQ-H&N35). STUDY DESIGN Retrospective Cohort Study. METHODS Retrospective, single-center cohort study utilizing a prospectively collected database of HNCA patients in a high-volume tertiary referral center. 736 HNCA patients more than 2 years from completion of treatment were identified. EORTC-QLQ-H&N35 data collected from at least one of three defined episodes of care were used. The m-HNSW uses three questions to form a 9-point dysphagia scale. A Cox proportional hazards model was used to determine the effect of the m-HNSW while controlling for demographics, tumor staging, site, and treatment. RESULTS Using data from 3, 6, 12 months from treatment, we analyzed a subset that included 328 patients. Three months after the completion of therapy, the m-HNSW score had a significant association with 1 (HR = 1.24, P = .0005) and 5 year survival (HR = 1.19, P = .0002) after accounting for body mass index. Six (HR = 1.14, P = .014) and 12 month (hazard ratio (HR) = 1.33, P
- Published
- 2021
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