1. Endoscopic versus microscopic stapes surgery outcomes: A meta‐analysis and systematic review
- Author
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Adrienn Németh, István János Tóth, László Lujber, Gábor Varga, István Szanyi, Noémi Gede, István Pap, Péter Révész, Imre Gerlinger, Zsolt Szakács, Péter Hegyi, Alexandros Koukkoullis, and Kinga Harmat
- Subjects
Microsurgery ,medicine.medical_specialty ,Funnel plot ,business.industry ,medicine.medical_treatment ,Perforation (oil well) ,Endoscopy ,Publication bias ,Odds ratio ,Stapes Surgery ,Stapedectomy ,medicine.disease ,Confidence interval ,Surgery ,03 medical and health sciences ,Treatment Outcome ,0302 clinical medicine ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Meta-analysis ,medicine ,Humans ,Otosclerosis ,030223 otorhinolaryngology ,business - Abstract
OBJECTIVE Compare intraoperative and postoperative outcomes of endoscopic and microscopic stapes surgery to provide objective evidence on whether the former is a better alternative than the latter. METHODS We performed a systematic review and meta-analysis for studies that compared endoscopic stapes surgery with microscopic stapes surgery. Only studies that met predetermined criteria were selected and assessed for bias and quality. Primary outcomes were postoperative air-bone gap (ABG) and chorda tympani nerve injury. Secondary outcomes were average operating time, tympanic membrane (TM) perforation, and postoperative taste disturbance, pain, and dizziness. We calculated pooled odds ratios (ORs) with 95% confidence intervals (CIs) for dichotomous outcomes and weighted mean difference (WMD) with 95% CI for continuous outcomes. A confidence interval starting above 1.0 was considered as statistically significant. I2 and χ2 tests were used to quantify statistical heterogeneity. We used funnel plots to look for publication bias and performed a sensitivity analysis. RESULTS Six nonrandomized cohort studies were eligible. The primary outcomes were ABG 20 dB: OR = 2.51 (95% CI: 0.77 to 8.22), and chorda tympani injury: OR = 3.51 (95% CI: 1.55 to 7.93). Secondary outcomes were taste: OR = 2.36 (95% CI: 1.01 to 5.51), average operation time: WMD = 0.14 (95% CI: -11.69 to 11.98), TM perforation: OR = 1.70 (95% CI: 0.44 to 6.58); pain: OR = 0.84 (95% CI: 0.36 to 1.96), and dizziness: OR = 2.15 (95% CI: 0.94 to 4.89). CONCLUSIONS Endoscopic stapes surgery is a valid alternative to the microscope. LEVEL OF EVIDENCE 2a Laryngoscope, 130: 2019-2027, 2020.
- Published
- 2019