1. EFFECT OF ANÆSTHESIA ON INTRACRANIAL PRESSURE IN PATIENTS WITH SPACE-OCCUPYING LESIONS
- Author
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W. Bryan, D.G. Mcdowall, JennettJ. Barker, and W. Fitch
- Subjects
Adult ,Anesthesia, Endotracheal ,medicine.medical_specialty ,Adolescent ,Intracranial Pressure ,Nitrous Oxide ,Brain Abscess ,Blood Pressure ,Fentanyl ,Isonipecotic Acids ,Methoxyflurane ,medicine ,Humans ,Neoplasm Metastasis ,Cerebral perfusion pressure ,Child ,Aged ,Cerebral Hemorrhage ,Encephalocele ,Intracranial pressure ,Phenoperidine ,Brain Diseases ,Blood Volume ,Brain Neoplasms ,business.industry ,Benperidol ,Glioma ,General Medicine ,Middle Aged ,Trichloroethylene ,Surgery ,Perfusion ,Skull ,medicine.anatomical_structure ,Child, Preschool ,Anesthesia ,Halothane ,Meningioma ,business ,Papilledema ,medicine.drug - Abstract
Volatile anaesthetic agents (halothane, trichloroethylene, and methoxyflurane) produced a greater rise in intracranial pressure in patients with intracranial space-occupying lesions than in patients with normal cerebrospinal-fluid pathways. Blood-pressure was reduced and cerebral perfusion fell strikingly. The increased intracranial pressure would be expected to accentuate internal brain hernias and, if the skull were opened, to result in difficult operating conditions and external herniation of the brain.
- Published
- 1969
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