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Your search keyword '"Ching-Jer Chang"' showing total 19 results
Start Over Author "Ching-Jer Chang" Journal the journal of organic chemistry
19 results on '"Ching-Jer Chang"'

1. Ohioensins: novel benzonaphthoxanthenones from Polytrichum ohioense

Author

Guo Qiang Zheng, John M. Cassady, David K. Ho, Jon Clardy, Ching Jer Chang, and Thomas J. Stout

Subjects
chemistry.chemical_classification, biology, Chemistry, Stereochemistry, Organic Chemistry, Tumor cells, Fractionation, biology.organism_classification, Chemical correlation, Polytrichaceae, Polycyclic compound, Spectral analysis, Polytrichum ohioense, Two-dimensional nuclear magnetic resonance spectroscopy
Abstract

Ohioensins A (1), B (2), C (3), D (4), and E (6), containing the novel polycyclic skeleton of (7bβ,-12bα,14cα)-7b,12b,13,14c-tetrahydro-14H-benzo[c]naphtho[2,1,8-mna]xanthen-14-one,have been isolated from the moss Polytrichum ohioense (Polytrichaceae) following bioassay-directed fractionation. The structures and relative stereochemistry of ohioensins were established on the basis of spectral analysis (UV, IR, MS, 2D NMR, and CD), chemical correlation, and X-ray diffraction

Published
1993
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2. Cytotoxic polyketides from Annona densicoma (annonaceae): 10,13-trans-13,14-erythro-densicomacin, 10,13-trans-13,14-threo-densicomacin, and 8-hydroxyannonacin

Author

Lizhen Xu, David K. Ho, Ching Jer Chang, John M. Cassady, and Jing Guang Yu

Subjects
biology, Chemistry, Stereochemistry, Organic Chemistry, Diastereomer, Biological activity, Nuclear magnetic resonance spectroscopy, Carbon-13 NMR, biology.organism_classification, Polyketide, Annonaceae, Cytotoxic T cell, Organic chemistry, Annona
Abstract

Three new linear polyketides, 10,13-trans-13,14-erythro-densicomacin (1), 10,13-trans-13,14-threo-densicomacin (2), and 8-hydroxyannonacin (3), and a known polyketide goniothalamicin were isolated from the stem bark of the Peruvian plant Annona densicoma Mart (Annonaceae). Their structures were elucidated on the basis of UV, IR, 1 H and 13 C NMR, and mass spectrometry data of the natural compounds and their derivatives. These polyketides are cytotoxic against human tumor cells in culture

Published
1992
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5. Mutactin, a novel polyketide from Streptomyces coelicolor. Structure and biosynthetic relationship to actinorhodin

Author

A. Adefarati, Paul J. Keller, John M. Beale, J. Gallucci, Ching-Jer Chang, X. G. He, H. L. Zhang, S. P. Cole, and Heinz G. Floss

Subjects
Polyketide, chemistry.chemical_compound, biology, Biochemistry, Stereochemistry, Streptomycetaceae, Chemistry, Organic Chemistry, Streptomyces coelicolor, Actinomycetales, biology.organism_classification, Actinorhodin
Abstract

La mutactin a ete isolee de Streptomyces coelidor et sa structure a ete etudiee par spectrometrie

Published
1990
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10. Biosynthesis of boromycin

Author

Ching-Jer Chang, Tom S. S. Chen, and Heinz G. Floss

Subjects
Boromycin, chemistry.chemical_compound, Biochemistry, Biosynthesis, Chemistry, Organic Chemistry
Published
1981
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16. Chemistry and selective cytotoxicity of annonacin-10-one, isoannonacin, and isoannonacin-10-one. Novel polyketides from Annona densicoma (Annonaceae)

Author

Jing Guang Yu, John M. Cassady, Lizhen Xu, and Ching Jer Chang

Subjects
chemistry.chemical_classification, Ketone, Cytotoxicity test, biology, Stereochemistry, Organic Chemistry, Annonacin, Biological activity, biology.organism_classification, Selective cytotoxicity, Isoannonacin, chemistry.chemical_compound, chemistry, Annonaceae, Annona
Abstract

Purification de trois composes polycetoniques extraits de Annona densicoma; analyse structurale; tests de cytotoxicite sur differentes lignees cellulaires de mammiferes

Published
1989
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18. Application of long-range spin-spin couplings in biosynthetic studies

Author

Laurence H. Hurley, Milton J. Zmijewski, Heinz G. Floss, and Ching jer Chang

Subjects
Range (particle radiation), Benzodiazepinones, Antifungal Agents, Magnetic Resonance Spectroscopy, Condensed matter physics, Chemistry, Anthramycin, Organic Chemistry, Pyrrolnitrin, Spin-½
Published
1976

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