1. Single-center analysis of patients with frontal fibrosing alopecia: evidence for hypothyroidism and a good quality of life
- Author
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Nadja Zöller, Markus Meissner, Roland Kaufmann, Manuela Denise Maier, and Eva Maria Valesky
- Subjects
medicine.medical_specialty ,Medicine (General) ,Clinical Research Reports ,Frontal fibrosing alopecia (FFA) ,Scarring alopecia ,030204 cardiovascular system & hematology ,Single Center ,Biochemistry ,03 medical and health sciences ,0302 clinical medicine ,R5-920 ,hairline ,Quality of life ,Hypothyroidism ,Germany ,Epidemiology ,Medicine ,Humans ,thyroid disease ,atopic predisposition ,Aged ,postmenopausal ,business.industry ,Frontal fibrosing alopecia ,Thyroid disease ,Incidence ,Biochemistry (medical) ,Alopecia ,Cell Biology ,General Medicine ,medicine.disease ,Prognosis ,Dermatology ,Fibrosis ,body regions ,quality of life ,030220 oncology & carcinogenesis ,Disease Progression ,Female ,business ,Follow-Up Studies - Abstract
Objective Frontal fibrosing alopecia (FFA) is an underestimated scarring alopecia. This study aimed to examine epidemiological information, as well as predilection sites, associated diseases, and responses to therapy of patients with FFA. We also aimed to determine whether the extent or duration of disease correlated with the quality of life (QoL). Methods Twelve outpatients with FFA for > 2 years were analyzed. The Erlanger atopic score and the Functional Assessment of Non-life-threatening Conditions (FANLTC) for QoL-assessment were used as scoring systems. Results All patients were women with a mean age of 70.3 years. Most patients did not have any symptoms during their disease progression and no therapy that was used showed any significant effects. FFA was associated with hypothyroidism. There were no correlations between hairline regression, duration of disease, atopic disposition, and QoL. The overall QoL was good. Conclusions The present study shows that there is no correlation between the extent of FFA and QoL or atopic predisposition. There is a strong correlation between the incidence of thyroid disease and FFA.
- Published
- 2018