1. Clinical features and prognosis of patients with idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease
- Author
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Hyun Kyung Lee, Youngwhan Kim, C. S. Park, Moo Suk Park, Sang Hoon Lee, Song Yee Kim, Joung-Jun Park, S. H. Jeong, H. L. Lee, Jae-Dam Lee, S. T. Uh, Dong Soon Kim, Y. H. Kim, Jong Wook Shin, S. W. Park, M. P. Chung, Yangjin Jegal, J. W. Song, and Yong Bum Park
- Subjects
Pulmonary and Respiratory Medicine ,Adult ,Male ,medicine.medical_specialty ,Vital capacity ,Vital Capacity ,Pulmonary function testing ,Idiopathic pulmonary fibrosis ,FEV1/FVC ratio ,Pulmonary Disease, Chronic Obstructive ,Interquartile range ,Internal medicine ,Forced Expiratory Volume ,Republic of Korea ,medicine ,Humans ,Registries ,Idiopathic interstitial pneumonia ,Aged ,COPD ,business.industry ,Interstitial lung disease ,respiratory system ,Middle Aged ,medicine.disease ,humanities ,Idiopathic Pulmonary Fibrosis ,respiratory tract diseases ,Infectious Diseases ,Female ,business - Abstract
BACKGROUND Idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) share common risk factors. They could therefore be expressed in a single patient. However, the prevalence, clinical characteristics and prognosis of individuals with comorbid IPF and COPD are not known. METHOD From 2003 to 2007, the Korean Interstitial Lung Disease Study Group created a register for idiopathic interstitial pneumonia using 2002 ATS/ERS (American Thoracic Society/European Respiratory Society) criteria. Of the 1546 IPF patients assessed, 143 had decreased lung function consistent with COPD (IPF-COPD). COPD was diagnosed based on age (≥40 years) and pulmonary function (forced expiratory volume in 1 sec [FEV1]/forced vital capacity [FVC] ratio RESULTS The median age of the IPF-COPD group was 71.0 years (interquartile range 66.0-76.0); most patients were male (88.1%). FVC (%) was significantly higher in the IPF-COPD group; however, FEV1 (%) was significantly lower in the IPF-COPD group (P CONCLUSION The prevalence of IPF-COPD was estimated to be ∼9.2% among all IPF patients; prognosis of patients with IPF-COPD was not worse than those with IPF alone. .
- Published
- 2019