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Start Over Descriptor "Muscle dysfunction" Journal the faseb journal
9 results on '"Muscle dysfunction"'

1. Manipulating Levels of Stress‐Response Proteins in a Drosophila Model of Myosin‐Based Inclusion Body Myopathy 3 Worsens Muscle Dysfunction

Author

Jennifer A. Suggs, D. Brian Foster, Girish C. Melkani, Anju Melkani, Sanford I. Bernstein, and Kimberley Manalo

Subjects
Fight-or-flight response, Inclusion body myopathy, biology, Muscle dysfunction, Myosin, Genetics, Drosophila (subgenus), biology.organism_classification, Molecular Biology, Biochemistry, Biotechnology, Cell biology
Published
2020
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3. Senescence in Myoblasts; Role in Age‐Related Muscle Dysfunction

Author

Aphrodite Vasilaki, Caroline Amy Staunton, Anne McArdle, and Shahjahan Shigdar

Subjects
0301 basic medicine, Senescence, medicine.medical_specialty, Biology, Biochemistry, 03 medical and health sciences, 030104 developmental biology, Endocrinology, Internal medicine, Muscle dysfunction, Age related, Genetics, medicine, Myocyte, Molecular Biology, Biotechnology
Published
2018
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4. Loss of mitochondrial phosphate carrier in skeletal muscle: dissociation of muscle dysfunction from lower ADP phosphorylating potential

Author

Lauren Anderson-Pullinger, Erin L. Seifert, and Yana Sharpadskaya

Subjects
Biophysics, Skeletal muscle, Phosphate, Biochemistry, Dissociation (chemistry), chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Muscle dysfunction, Genetics, medicine, Phosphorylation, Molecular Biology, Biotechnology
Published
2018
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6. Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline

Author

Leslie M. Fischer, Steven H. Zeisel, Michael V. Milburn, Wei Jia, Kerry Ann Da Costa, Wei Sha, Kay A. Lawton, and Alvin Berger

Subjects
medicine.medical_specialty, Biology, Biochemistry, Choline, Research Communications, Fats, chemistry.chemical_compound, Metabolomics, Predictive Value of Tests, Internal medicine, Genetics, medicine, Humans, Molecular Biology, chemistry.chemical_classification, Liver Diseases, Fatty liver, Organ dysfunction, medicine.disease, Choline Deficiency, Diet, Metabolomic profiling, Endocrinology, Liver, chemistry, Muscle dysfunction, medicine.symptom, Liver dysfunction, Essential nutrient, Biotechnology
Abstract

Choline is an essential nutrient, and deficiency causes liver and muscle dysfunction. Common genetic variations alter the risk of developing organ dysfunction when choline deficient, probably by causing metabolic inefficiencies that should be detectable even while ingesting a normal choline-adequate diet. We determined whether metabolomic profiling of plasma at baseline could predict whether humans will develop liver dysfunction when deprived of dietary choline. Fifty-three participants were fed a diet containing 550 mg choline/70 kg/d for 10 d and then fed

Published
2010
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7. Cigarette smoke impairs the in situ fatigue resistance of locomotor skeletal muscle in mice (1102.18)

Author

Ellen C. Breen, Breanna M. Trisko, Peter D. Wagner, and Leonardo Nogueira

Subjects
medicine.medical_specialty, COPD, business.industry, Skeletal muscle, Exercise intolerance, Anatomy, medicine.disease, Biochemistry, respiratory tract diseases, Fatigue resistance, Endocrinology, medicine.anatomical_structure, Muscle dysfunction, Internal medicine, Genetics, medicine, Cigarette smoke, Skeletal muscle fatigue, medicine.symptom, business, Molecular Biology, Biotechnology
Abstract

Muscle dysfunction is thought to contribute to exercise intolerance in smokers with COPD. In this study, cigarette smoke (CS) was hypothesized to impair skeletal muscle fatigue resistance. To test ...

Published
2014
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8. Paraquat exposure induces dorsiflexor muscle dysfunction and dopaminergic modification resembling Parkinson's disease

Author

Mohamed A. Fahim, Abderrahim Nemmar, Safa Shehab, Abdu Adem, and Mohamed Y. Hasan

Subjects
medicine.medical_specialty, Parkinson's disease, business.industry, Dopaminergic, medicine.disease, Biochemistry, chemistry.chemical_compound, Endocrinology, Paraquat, chemistry, Muscle dysfunction, Internal medicine, Genetics, medicine, business, Molecular Biology, Biotechnology
Published
2012
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