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2. Administration of Losartan Improves Myocardial Functional Performance in Rats with High‐Fat Diet‐Induced Obesity

Author

Nayara Araújo Muzili, Gabriel Elias Ota, Katashi Okoshi, Marina Politi Okoshi, Camila Souza de Morais, Paula Felippe Martinez, Antonio Carlos Cicogna, Marcelo Diarcadia Mariano Cezar, Dijon Henrique Salomé de Campos, Silvio A. Oliveira Junior, and Marianna Rabelo Carvalho

Subjects
High fat diet induced obesity, medicine.medical_specialty, Losartan, Endocrinology, business.industry, Internal medicine, Genetics, Medicine, business, Molecular Biology, Biochemistry, Biotechnology, medicine.drug
Published
2019
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4. Administration of Losartan Improves Myocardial Functional Performance in Rats with High‐Fat Diet‐Induced Obesity

Author

Oliveira, Silvio Assis, primary, Araújo Muzili, Nayara, additional, Carvalho, Marianna Rabelo, additional, Campos, Dijon Henrique Salomé, additional, Cezar, Marcelo Diarcádia Mariano, additional, Ota, Gabriel Elias, additional, Morais, Camila Souza, additional, Okoshi, Katashi, additional, Okoshi, Marina Politi, additional, Cicogna, Antonio Carlos, additional, and Martinez, Paula Felippe, additional

Published
2019
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5. AT1 receptor blockade modifies MAPKs expression and attenuates myocardial remodeling in rats subjected to high‐fat diet‐induced obesity

Author

Oliveira‐Junior, Silvio Assis, primary, Carvalho, Marianna R, additional, Ota, Gabriel E, additional, Morais, Camila S, additional, Pagan, Luana U, additional, Gomes, Mariana J, additional, Martinez, Paula F, additional, Fernandes, Tiago, additional, Oliveira, Edilamar M, additional, Okoshi, Marina P, additional, Okoshi, Katashi, additional, Campos, Dijon H S, additional, and Cicogna, Antonio C, additional

Published
2017
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9. Correlation Between Diet Macronutrients and Metabolic plus Cardiovascular Abnormalities in Spontaneously Hypertensive Rats

Author

Paula F. Martinez, Silvio de Oliveira Junior, Katashi Okoshi, Dijon Henrique Salomé de Campos, Nilza Regina da Silva, Sérgio Tosi Rodrigues, Carlos Roberto Padovani, Antonio Carlos Cicogna, and Marina Politi Okoshi

Subjects
medicine.medical_specialty, business.industry, musculoskeletal system, Biochemistry, Correlation, Endocrinology, Internal medicine, cardiovascular system, Genetics, medicine, cardiovascular diseases, business, Molecular Biology, circulatory and respiratory physiology, Biotechnology, Hormone
Abstract

This study analyzed the association between dietary macronutrients and metabolic, hormonal, as well as cardiovascular responses in spontaneously hypertensive rats (SHR). SHR (n=20) were submitted t...

Published
2015
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10. Renin‐angiotensin‐aldosterone system blockade ameliorates myocardial and ventricular function of rats with diabetes mellitus

Author

C. M. Rosa, Rodrigo Gimenes, Dijon Henrique Salomé de Campos, Luana Urbano Pagan, Katashi Okoshi, Felipe C. Damatto, Marcela Nunes, Marina Politi Okoshi, Mariana Janini Gomes, Marcelo Diarcadia Mariano Cezar, Ricardo Luiz Damatto, and Camila Bonomo

Subjects
medicine.medical_specialty, Ventricular function, business.industry, medicine.disease, Biochemistry, Blockade, Losartan, Internal medicine, Diabetes mellitus, Renin–angiotensin system, cardiovascular system, Genetics, medicine, Cardiology, Cardiac structure, business, Molecular Biology, Biotechnology, medicine.drug
Abstract

The objective of this study was to evaluate the influence of renin-angiotensin-aldosterone system (RAAS) blockade with losartan (LOS) on cardiac structure and function of rats with diabetes mellitu...

Published
2015
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11. Obesity in Saturated Fat Diet Does Not Alter the Proteins Involved in Myocardial Calcium Transit

Author

Antonio Carlos Cicogna, Danielle Fernandes Vileigas, Danielle da Silva, Marina Politi Okoshi, Dijon Henrique Salomé de Campos, Scarlet Marques de Oliveira, Adriana Fernandes de Deus, Luana Urbano Pagan, and Paula Grippa Sant’Ana

Subjects
medicine.medical_specialty, Chemistry, Saturated fat, medicine.disease, Biochemistry, Obesity, Endocrinology, Internal medicine, Genetics, medicine, Phosphorylation, sense organs, Myocardial calcium, skin and connective tissue diseases, Molecular Biology, Biotechnology
Abstract

The aim of this study was to test the hypothesis that obesity by saturated high-fat diet leads to changes in the expression and / or phosphorylation of proteins related to myocardial calcium handli...

Published
2015
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12. Exercise training and MAPK protein expression in rats with heart failure (LB521)

Author

Luana Urbano Pagan, Paula F. Martinez, Camila Bonomo, Mariana Janini Gomes, Ana Matsimbe, Marina Politi Okoshi, Dijon Henrique Salomé de Campos, Ricardo Luiz Damatto, Buanansa Juma, Aline R. R. Lima, and Katashi Okoshi

Subjects
Soleus muscle, medicine.medical_specialty, business.industry, sed, Skeletal muscle, medicine.disease, Biochemistry, medicine.anatomical_structure, Ventricle, Heart failure, Internal medicine, Genetics, medicine, Physical therapy, Cardiology, Analysis of variance, Transthoracic echocardiogram, Treadmill, business, Molecular Biology, computer, Biotechnology, computer.programming_language
Abstract

This study examined whether exercise training influences physical capacity, cardiac remodeling, and mitogen-activated protein kinases (MAPK) expression in skeletal muscle of rats with pressure overload-induced heart failure. Methods: Twenty weeks after inducing aortic stenosis (AS), Wistar rats were assigned to four groups (n=8): sham sedentary (Sed), Sham exercise (Ex), AS, and AS-Ex. Physical training was performed 5 times per week for 8 weeks in a treadmill. Physical performance was assessed by exercise test on a treadmill with a gradual speed increase before and after the training period. Transthoracic echocardiogram was performed before and after training. Protein expression was analyzed by Western blot in soleus muscle. Statistical analyzes: ANOVA and Tukey test. Results: Before training, echocardiographic parameters did not differ between AS and AS-Ex groups. Physical training improved functional capacity without changing cardiac structures or left ventricular function. Right ventricle weight was h...

Published
2014
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13. Inhibition of the Sodium‐Glucose Co‐Transporter Protein Type 2 Decreases Oxidative Stress and Improves Cardiac Remodeling in Rats with Diabetes Mellitus

Author

Rosa, Camila Moreno, primary, Campos, Dijon Henrique Salome, additional, Reyes, David Rafael, additional, Pagan, Luana Urbano, additional, Gomes, Mariana Janini, additional, Damatto, Felipe, additional, Fernandes, Ana Angélica Henrique, additional, Okoshi, Marina Politi, additional, and Okoshi, Katashi, additional

Published
2016
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14. Long‐Term Exposure of Obesity Induced by Unsaturated High‐Fat Diet promotes Cardiac Dysfunction and Increase of Myocardial Collagen

Author

André Soares Leopoldo, Mario Mateus Sugizaki, Dijon Henrique Salomé de Campos, Ana Paula Lima Leopoldo, Carlos Roberto Padovani, Andre F. Nascimento, Antonio Carlos Cicogna, and Danielle da Silva

Subjects
medicine.medical_specialty, business.industry, High fat diet, medicine.disease, Biochemistry, Obesity, Cardiac dysfunction, Endocrinology, Internal medicine, Genetics, medicine, business, Molecular Biology, Biotechnology
Published
2013
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15. Influence of long‐term exposure of obesity on protein expression of myocardial calcium handling

Author

Dijon Henrique Salomé de Campos, Ana Paula Lima-Leopoldo, André Soares Leopoldo, Antonio Carlos Cicogna, Adriana Fernandes de Deus, Carlos Alves, Paula Paccielli Freire, Danielle Cristina Tomaz da Silva, Andre F. Nascimento, Mario Mateus Sugizaki, and Renata de Azevedo Melo Luvizotto

Subjects
medicine.medical_specialty, business.industry, medicine.disease, Biochemistry, Obesity, Protein expression, Term (time), Endocrinology, Internal medicine, Genetics, Medicine, Myocardial calcium, business, Molecular Biology, Biotechnology
Published
2013
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16. Effects of a high‐fat diet on the cardiac dysfunction and energy metabolism in rats with supravalvar aortic stenosis

Author

Antonio Carlos Cicogna, Carlos Roberto Padovani, Danielle Cristina Tomaz da Silva, Ana Angélica Henrique Fernandes, Katashi Okoshi, Loreta Casquel de Tomasi, André Ferreira do Nascimento, and Dijon Henrique Salomé de Campos

Subjects
medicine.medical_specialty, business.industry, Energy metabolism, medicine.disease, Biochemistry, Cardiac dysfunction, Stenosis, Fat diet, Internal medicine, Genetics, Cardiology, medicine, business, Molecular Biology, Biotechnology
Published
2013
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17. Influence of physical exercise on cardiac structure and function of spontaneously hypertensive rats

Author

Luana Urbano Pagan, Marcelo Diarcadia Mariano Cezar, Camila Bonomo, Daniele M. Guizoni, Dijon Henrique Salomé de Campos, R. L. Damatto, Katashi Okoshi, Rodrigo Gimenes, Aline R. R. Lima, and Marina Politi Okoshi

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Genetics, medicine, Cardiology, Physical exercise, Cardiac structure, business, Molecular Biology, Biochemistry, Function (biology), Biotechnology
Published
2012
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18. TOTAL ANTIOXIDANT CAPACITY, LIPID PEROXIDATION, BIOCHEMICAL PARAMETERS AND BLOOD PRESSURE IN GENETICALLY OBESE RATS

Author

Camila Renata Corrêa, Mariana Gobbo Braz, Antonio Carlos Cicogna, Mirelle de Faria Jacob, Dijon Henrique Salomé de Campos, Ana Lúcia dos Anjos Ferreira, Damiana Tortolero Pierine, and Taina Teixeira Ortega

Subjects
medicine.medical_specialty, Biochemistry, Lipid peroxidation, Antioxidant capacity, chemistry.chemical_compound, Blood pressure, Endocrinology, chemistry, Internal medicine, Genetics, medicine, Molecular Biology, Biotechnology
Published
2011
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20. Renin‐angiotensin‐aldosterone system blockade ameliorates myocardial and ventricular function of rats with diabetes mellitus

Author

Pagan, Luana, primary, Gimenes, Rodrigo, additional, Damatto, Ricardo, additional, Cezar, Marcelo, additional, Rosa, Camila, additional, Nunes, Marcela, additional, Damatto, Felipe, additional, Campos, Dijon, additional, Gomes, Mariana, additional, Bonomo, Camila, additional, Okoshi, Marina, additional, and Okoshi, Katashi, additional

Published
2015
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26. Influence of physical exercise on cardiac structure and function of spontaneously hypertensive rats

Author

Pagan, Luana Urbano, primary, Damatto, Ricardo Luis, additional, Cezar, Marcelo Diarcadia Mariano, additional, Gimenes, Rodrigo, additional, Campos, Dijon Henrique Salomé, additional, Lima, Aline Regina Ruiz, additional, Bonomo, Camila, additional, Guizoni, Daniele Mendes, additional, Okoshi, Marina Politi, additional, and Okoshi, Katashi, additional

Published
2012
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27. EFFECTS OF GROWTH HORMONE ADMINISTRATION ON CARDIAC REMODELING PROCESS IN RATS WITH AORTIC STENOSIS‐INDUCED HEART FAILURE

Author

Lima, Aline Regina Ruiz, primary, Damatto, Ricardo, additional, Campos, Dijon, additional, Martinez, Paula, additional, Guizoni, Daniele, additional, Bonomo, Camila, additional, Cézar, Marcelo, additional, Silva, Frederico, additional, Zanati, Silméia, additional, Campana, Alvaro, additional, Okoshi, Katashi, additional, and Okoshi, Marina, additional

Published
2012
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28. Early rather than late aldosterone blockade improves myocardial function in spontaneously hypertensive rats without heart failure

Author

CEZAR, MARCELO DIARCADIA MARIANO, primary, Junior, Silvio, additional, Martinez, Paula, additional, Damatto, Ricardo, additional, Lima, Aline, additional, Bonomo, Camila, additional, Guizoni, Daniele, additional, Campos, Dijon, additional, Moretto, Fernanda, additional, Blotta, Daniella, additional, Rosa, Camila, additional, Campana, Alvaro, additional, Okoshi, Marina, additional, and Okoshi, Katashi, additional

Published
2012
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