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Iron deficiency (ID) in otherwise healthy adults can impair perceptual and cognitive functioning, along with brain dynamics (as measured by EEG). We used structural equation modeling (SEM) to test the hypothesis that changes in iron status lead to changes in brain functioning and then to changes in behavioral measures. The data used here were taken from 54 ID (sFt

Iron deficiency (ID) is prevalent among female athletes and poor dietary intake is one of several contributing factors. The goal of this cross-sectional analysis was to examine the relationships be...

Nutritional deficiencies have been correlated with cognitive deficits, and animal studies specifically show memory deficiencies. Studies link EEG measures of brain function to behavioral measures o...

Objective: To examine the effects of an iron-biofortified bean intervention on physical performance in Rwandan women assessed by VO2max. Methods: 145 Rwandan women (18-26 years) were randomized to ...

Iron deficiency (ID) is a highly prevalent micronutrient deficiency, affecting individuals in both developing and developed countries. Previous research on children with ID report deficits in atten...

Objective: To quantify the effect on weight gain of a 4.5 months feeding trial intended to replace the subjects’ regular meals. Methods: 145 Rwandan women (18-26 years) in a double-blind feeding trial were randomized to receive either iron-biofortified beans or traditional beans daily for 4.5 months. During the feeding period, the subjects were served 175 g of beans per meal, for lunch and dinner, plus ad libitum consumption of side dishes; they were allowed to consume more beans if desired. Blood biomarkers and anthropometry were measured before and after the feeding period. General linear models were used to evaluate the effect of the intervention on weight gain. Results: On average, the women consumed 200 g of beans (358 kcals) per meal. After the 4.5 months feeding period, 25% of the women gained 蠅 3 kg in body weight. Both the control and the treatment group consumed the same amount of beans per meal, with the treatment group having a significantly (p>.001) greater increase in iron status. The more b...

Iron deficiency affects an estimated one in four persons globally and has been shown to impair cognition, though this relation in adolescents has not been substantiated. In a double-blind efficacy trial, Indian adolescents (n=264) were randomized to groups consuming either high-iron biofortified (Fe-PM) or normal-iron (CN-PM) pearl millet. Here, we present results from a subset (n=161; 12-16 y; 59 F) who performed tests of perceptual and cognitive functioning before and after 6 months of daily pearl millet consumption. Three speeded tests were administered: 1) Simple Reaction Time (SRT), a test of perceptual processing speed, 2) Go/No-Go (GNG), a test of inhibitory control and 3) Attentional Network Task (ANT), a test of three critical functions of attention (low-level attentional capture, high-level attentional selection, and volitional control under distraction). In the intention-to-treat analyses, improvement was greater, though not statistically significant, in the Fe-PM vs. the CN-PM group for all th...

Iron deficiency (ID) is a highly prevalent micronutrient deficiency, affecting individuals world wide. Evidence suggests that brain iron deficiency with and without anemia may disrupt myelination, ...

Objective: To examine the efficacy of an iron biofortified bean intervention on iron status in iron depleted young women. Methods: 257 Rwandan university women (18-27 y) with screening ferritin

The relation between iron status and attentional functioning was explored in Rwandan university women who participated in a RCT assessing the efficacy of biofortified beans on improving iron status. A subsample of the subjects (n=157, 18-27 y) underwent testing of perceptual and cognitive functioning at three time points. Here, we present cross-sectional analyses of baseline performance on the 3 attentional tasks: 1) Simple Reaction Time (SRT): test of perceptual and processing speed; 2) Go/No-Go (GNG): test of inhibitory control; 3) Attentional Network Task (ANT): test of 3 critical functions of attention: low-level attentional capture (alerting), high-level attentional selection (orienting), and volitional control under distraction (conflict). Women were categorized as: iron sufficient (IS), iron deficient (ID) or iron deficient anemic (IDA). SRT reaction times were longer in the IDA and ID grps vs. the IS grp (p

No definition of iron deficiency (ID) exists for infants under 12 mo, but young infants (4-6 mo) are at risk of anemia and depleted iron stores. Nutritional insults during peak brain development (l...

Iron deficiency (ID) has numerous effects on individual functioning, including perception and cognition. Research has documented substantial deficits with ID and improvements with iron repletion. H...

Previous research showed that consuming iron-fortified salt improves iron status. Interactions between iodine and iron in double-fortified salt (DFS) may alter the effect of DFS on iodine status. A...