1. Living Donor Liver Transplantation in a Hepatitis B Patient with Acute on Chronic Liver Failure Accompanying Hepatocellular Carcinoma
- Author
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Seong Gyu Hwang, Yun Bin Lee, Kyu Sung Rim, Joo Ho Lee, Hana Park, and Hee Jin Hong
- Subjects
medicine.medical_specialty ,Cirrhosis ,business.industry ,medicine.medical_treatment ,030230 surgery ,Liver transplantation ,Milan criteria ,Hepatitis B ,medicine.disease ,Chronic liver disease ,Gastroenterology ,03 medical and health sciences ,Liver disease ,0302 clinical medicine ,Internal medicine ,Hepatocellular carcinoma ,medicine ,030211 gastroenterology & hepatology ,business ,Survival rate - Abstract
Acute clinical deterioration in patients with chronic liver disease is called acute on chronic liver failure (ACLF). Principles of management of ACLF consist of early identifying etiology of liver disease, rapid intervention of precipitating event and discreet intensive cares. Despite medical intensive cares, if liver failure progresses, liver transplantation could be the other option. Also, liver transplantation is the only treatment that offers a chance of cure for hepatocellular carcinoma (HCC) and the underlying liver cirrhosis simultaneously. Emergent living donor liver transplantation (LDLT) can be performed for patients with acute liver failure and improves survival rate, especially in circumstances which liver graft is often not available because of deceased donors are not affordable. Here, we describe a chronic hepatitis B patient who developed ACLF accompanying early HCC. Because he did not improved with medical care, he received emergent LDLT. After LDLT, he showed great improvement without critical complications. (Ewha Med J 2016;39(3):76-80) Received July 29, 2015 Accepted May 18, 2016
- Published
- 2016