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The electrochemical behaviour of chlorpromazine hydrochloride (CPZ-HCI) in sulphuric acid was investigated voltammetrically using ruthenium electrodes and it was subsequently determined by the same method. From the recorded voltammograms it was concluded that CPZ-HCI can be determined in the concentration range 2 x 10(-4)-8 x 10(-4) M (71-284. 3 micrograms ml-1). The proposed voltammetric method was applied to the determination of CPZ-HCI in tablets used for neuroleptic purposes in Turkey; the amount of effective compound was found to be within the ranges given for a pharmacopoeial procedure.

The electrochemical oxidation of bamipine hydrochloride in sulphuric acid and phosphate buffer solutions was examined using a platinum electrode. Two different reaction mechanisms for two different potential regions are proposed. It was shown that the determination of the drug by this method is feasible.