1. Smoking-related health risks among persons with HIV in the strategies for management of antiretroviral therapy clinical trial
- Author
-
Lifson, Alan R., Neuhaus, Jacqueline, Arribas, Jose Ramon, van den Berg-Wolf, Mary, Labriola, Ann M., and Read, Timothy R.H.
- Subjects
Smoking cessation programs -- Management ,HIV patients -- Behavior ,HIV patients -- Care and treatment ,Public health administration -- Research ,Highly active antiretroviral therapy -- Management ,Company business management ,Government ,Health care industry - Abstract
Objectives. We sought to determine smoking-related hazard ratios (HRs) and population-attributable risk percentage (PAR%) for serious clinical events and death among HIV-positive persons, whose smoking prevalence is higher than in the general population. Methods. For 5472 HIV-infected persons enrolled from 33 countries in the Strategies for Management of Antiretroviral Therapy clinical trial, we evaluated the relationship between baseline smoking status and development of AIDS-related or serious non-AIDS events and overall mortality. Results. Among all participants, 40.5% were current smokers and 24.8% were former smokers. Adjusted HRs were higher for current than for never smokers for overall mortality (2.4; P Conclusions. Smoking contributes to substantial morbidity and mortality in this HIV-infected population. Providers should routinely integrate smoking cessation programs into HIV health care. (Am J Public Health. 2010;100: 1896-1903. doi: 10.2105/AJPH.2009.188664)
- Published
- 2010