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Your search keyword '"Deedwania, Prakash"' showing total 25 results
Start Over Author "Deedwania, Prakash" Journal the american journal of medicine
25 results on '"Deedwania, Prakash"'

1. Systolic Blood Pressure and Outcomes in Older Patients with HFpEF and Hypertension

Author

Faselis, Charles, Lam, Phillip H, Zile, Michael R, Bhyan, Poonam, Tsimploulis, Apostolos, Arundel, Cherinne, Patel, Samir, Kokkinos, Peter, Deedwania, Prakash, Bhatt, Deepak L, Zeng-Trietler, Qing, Morgan, Charity J, Aronow, Wilbert S, Allman, Richard M, Fonarow, Gregg C, and Ahmed, Ali

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Cardiovascular, Aging, Patient Safety, Clinical Research, Hypertension, Aged, Aged, 80 and over, Blood Pressure, Cohort Studies, Female, Heart Failure, Humans, Inpatients, Male, Medicare, Registries, Treatment Outcome, United States, All-cause mortality, Heart failure with preserved ejection fraction, Readmission, Systolic blood pressure, Heart failure with preserved ejection fraction (HFpEF), Readmission, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
Abstract

BackgroundNew hypertension and heart failure guidelines recommend that systolic blood pressure (SBP) in patients with heart failure with preserved ejection fraction (HFpEF) and hypertension be lowered to

Published
2021

8. Association of 30-Day All-Cause Readmission with Long-Term Outcomes in Hospitalized Older Medicare Beneficiaries with Heart Failure

Author

Arundel, Cherinne, Lam, Phillip H, Khosla, Rahul, Blackman, Marc R, Fonarow, Gregg C, Morgan, Charity, Zeng, Qing, Fletcher, Ross D, Butler, Javed, Wu, Wen-Chih, Deedwania, Prakash, Love, Thomas E, White, Michel, Aronow, Wilbert S, Anker, Stefan D, Allman, Richard M, and Ahmed, Ali

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Cardiovascular, Clinical Research, Prevention, Aging, Aged, Aged, 80 and over, Alabama, Case-Control Studies, Cohort Studies, Comorbidity, Coronary Artery Disease, Diabetes Mellitus, Female, Follow-Up Studies, Heart Failure, Hospitalization, Humans, Male, Medicare, Middle Aged, Mortality, Multivariate Analysis, Patient Readmission, Prognosis, Propensity Score, Proportional Hazards Models, Pulmonary Disease, Chronic Obstructive, Renal Insufficiency, Chronic, Treatment Outcome, United States, 30-Day all-cause readmission, All-cause mortality, Cost, Heart failure, Medicare beneficiaries, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
Abstract

BackgroundHeart failure is the leading cause for 30-day all-cause readmission. We examined the impact of 30-day all-cause readmission on long-term outcomes and cost in a propensity score-matched study of hospitalized patients with heart failure.MethodsOf the 7578 Medicare beneficiaries discharged with a primary diagnosis of heart failure from 106 Alabama hospitals (1998-2001) and alive at 30 days after discharge, 1519 had a 30-day all-cause readmission. Using propensity scores for 30-day all-cause readmission, we assembled a matched cohort of 1516 pairs of patients with and without a 30-day all-cause readmission, balanced on 34 baseline characteristics (mean age 75 years, 56% women, 24% African American).ResultsDuring 2-12 months of follow-up after discharge from index hospitalization, all-cause mortality occurred in 41% and 27% of matched patients with and without a 30-day all-cause readmission, respectively (hazard ratio 1.68; 95% confidence interval 1.48-1.90; P

Published
2016

9. Renin-Angiotensin System Inhibition and Lower 30-Day All-Cause Readmission in Medicare Beneficiaries with Heart Failure

Author

Sanam, Kumar, Bhatia, Vikas, Bajaj, Navkaranbir S, Gaba, Saurabh, Morgan, Charity J, Fonarow, Gregg C, Butler, Javed, Deedwania, Prakash, Prabhu, Sumanth D, Wu, Wen-Chih, White, Michel, Love, Thomas E, Aronow, Wilbert S, Fletcher, Ross D, Allman, Richard M, and Ahmed, Ali

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Cardiovascular, Heart Disease, Clinical Research, Good Health and Well Being, Aged, Aged, 80 and over, Alabama, Angiotensin Receptor Antagonists, Angiotensin-Converting Enzyme Inhibitors, Cause of Death, Female, Heart Failure, Hospitalization, Humans, Male, Medicare, Middle Aged, Mortality, Patient Readmission, Proportional Hazards Models, Protective Factors, Renin-Angiotensin System, Stroke Volume, United States, Ventricular Dysfunction, Left, ACEI or ARB, Heart failure, Hospital readmission, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
Abstract

BackgroundHeart failure is the leading cause for 30-day all-cause readmission, the reduction of which is a goal of the Affordable Care Act. There is a growing interest in understanding the impact of evidence-based heart failure therapy on 30-day all-cause readmission. In the current study, we examined the impact of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (ACEI-ARBs) on 30-day all-cause readmission in heart failure.MethodsOf the 1384 hospitalized Medicare beneficiaries with heart failure and left ventricular ejection fraction

Published
2016

10. Beta-blocker Use and 30-day All-cause Readmission in Medicare Beneficiaries with Systolic Heart Failure

Author

Bhatia, Vikas, Bajaj, Navkaranbir S, Sanam, Kumar, Hashim, Taimoor, Morgan, Charity J, Prabhu, Sumanth D, Fonarow, Gregg C, Deedwania, Prakash, Butler, Javed, Carson, Peter, Love, Thomas E, Kheirbek, Raya, Aronow, Wilbert S, Anker, Stefan D, Waagstein, Finn, Fletcher, Ross, Allman, Richard M, and Ahmed, Ali

Subjects
Clinical Research, Aging, Health Services, Heart Disease, Cardiovascular, Good Health and Well Being, Adrenergic beta-Antagonists, Aged, Aged, 80 and over, Cause of Death, Confidence Intervals, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Follow-Up Studies, Heart Failure, Systolic, Hospital Mortality, Humans, Kaplan-Meier Estimate, Male, Medicare, Middle Aged, Patient Discharge, Patient Protection and Affordable Care Act, Patient Readmission, Proportional Hazards Models, Risk Assessment, Survival Analysis, Time Factors, Treatment Outcome, United States, Beta-blockers, Hospitalization, Older adults, Readmission, Systolic heart failure, Medical and Health Sciences, General & Internal Medicine
Abstract

BackgroundBeta-blockers improve outcomes in patients with systolic heart failure. However, it is unknown whether their initial negative inotropic effect may increase 30-day all-cause readmission, a target outcome for Medicare cost reduction and financial penalty for hospitals under the Affordable Care Act.MethodsOf the 3067 Medicare beneficiaries discharged alive from 106 Alabama hospitals (1998-2001) with a primary discharge diagnosis of heart failure and ejection fraction

Published
2015

13. Digoxin Use and Lower 30-day All-cause Readmission for Medicare Beneficiaries Hospitalized for Heart Failure

Author

Ahmed, Ali, Bourge, Robert C, Fonarow, Gregg C, Patel, Kanan, Morgan, Charity J, Fleg, Jerome L, Aban, Inmaculada B, Love, Thomas E, Yancy, Clyde W, Deedwania, Prakash, van Veldhuisen, Dirk J, Filippatos, Gerasimos S, Anker, Stefan D, and Allman, Richard M

Subjects
Clinical Research, Aging, Heart Disease, Cardiovascular, Aged, Aged, 80 and over, Cardiotonic Agents, Case-Control Studies, Chronic Disease, Digoxin, Drug Administration Schedule, Female, Heart Failure, Systolic, Humans, Male, Medicare, Patient Discharge, Patient Readmission, Treatment Outcome, United States, Heart failure, Hospital readmission, Medical and Health Sciences, General & Internal Medicine
Abstract

BackgroundHeart failure is the leading cause for hospital readmission, the reduction of which is a priority under the Affordable Care Act. Digoxin reduces 30-day all-cause hospital admission in chronic systolic heart failure. Whether digoxin is effective in reducing readmission after hospitalization for acute decompensation remains unknown.MethodsOf the 5153 Medicare beneficiaries hospitalized for acute heart failure and not receiving digoxin, 1054 (20%) received new discharge prescriptions for digoxin. Propensity scores for digoxin use, estimated for each of the 5153 patients, were used to assemble a matched cohort of 1842 (921 pairs) patients (mean age, 76 years; 56% women; 25% African American) receiving and not receiving digoxin, who were balanced on 55 baseline characteristics.ResultsThirty-day all-cause readmission occurred in 17% and 22% of matched patients receiving and not receiving digoxin, respectively (hazard ratio [HR] for digoxin, 0.77; 95% confidence interval [CI], 0.63-0.95). This beneficial association was observed only in those with ejection fraction

Published
2014

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