Search

Guanazine (3,4,5-triamino-1,2,4-triazole) is selectively nitrosated on C–NH 2 to produce nitrosoguanazine (3-nitrosamino-4,5-diamino-1,2,4-triazole). The nitrosoguanazine is used to prepare 5-azido-3-amino-1,2,4-triazole and nitrosoguanazine anion–Cu(II) complexes.

Core molecules based on benzene-, cubane-, and adamantane-polycarboxylates with peripheral polyazido substitution are reported. The first synthesis of 1,3-diazidoacetone and its conversion to the corresponding oxime, DNPH, and 2,2-dinitro derivatives is also reported.

The alkylation of glycoluril with methallyl dichloride and further functionalization of the resultant tetracyclic molecule to synthesize different molecular clefts is described.

N -acetyl-2-azetine has been found to undergo facile [4+2] cycloadditions with various dienes to give products of endo addition exclusively.

Photodimerization of N-acetyl-2-azetine to yield both possible head to head dimers with syn and anti geometries is described.

A facile, one-pot reaction between 3,4,5-triamino-1,2,4-triazole (guanazine) and cyanogen bromide provides a new high-nitrogen example of the 3H,9H-bis[1,2,4]triazolo[1,5-a:5′,1′-d][1,3,5]triazinium system, the 2,3,5,6-tetraamino-9-imino derivative (3) as a quaternary bromide salt.

Amidocubanes react with oxalyl chloride via a ring opening-addition process to give substituted norcubanes.

Reaction of diphenyl methylphosphonate with lithium alkoxides generated in situ from alcohols and butyllithium gives phenyl alkyl methylphosphonate diesters even with hindered alcohols and with high diastereoselectivity at phosphorus.

The structures of various perhalodiones available by isomerization of the Diels–Alder dimers of tetrachloro- and tetrabromocyclopentadienone have finally been determined unambiguously.

The syntheses of new 3,3-dinitro derivatives of the 1,5-diazocine ring system are described. Highly deactivated precursor ketones hexahydro-7,7-dinitro-1,5-bis(2- and 4-nitrobenzenesulfonyl)-1,5-diazocin-3(2 H )-ones ( 18 ) have been difluoraminated to the corresponding gem -bis(difluoramino)diazocines ( 19 ). The 1,5-bis(4-nitrobenzenesulfonyl)diazocine derivative undergoes N -nitrolysis with the protonitronium reagent formed in the nitric acid–trifluoromethanesulfonic acid–antimony pentafluoride system to produce 3,3-bis(difluoramino)octahydro-1,5,7,7-tetranitro-1,5-diazocine 2 (TNFX), containing nitramine, gem -dinitro, and gem -bis(difluoramino) structural components.