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Fluorogenic aromatic aldehydes bearing arylethynyl groups were developed. They were used for monitoring the reaction progress of organocatalytic aldol reactions in DMSO through an increase in the fluorescence intensity based on the formation of the florescent aldol product. The ratios of the fluorescence intensities of the aldols to the aldehydes were more than 300. These results suggest that the fluorescence assay system using the aldehyde is useful for the rapid identification of superior aldol catalysts and reaction conditions.

A new type of dendritic molecules, Gd–DTPA derivatives, which work as a functionalized ligand coordinating gadolinium(III) ion at the center of their frameworks with different terminal moieties on the molecular surfaces, was readily synthesized with high yield. The structures were established by 1H, 13C NMR, and mass spectral studies. In vitro studies showed them to have enhanced r1 value in albumin medium and good potentiality as MRI contrast agent.

The novel formation of anhydro -3-hydroxy-2,4-diphenyl-6-arylpyrylium hydroxide in the reaction of 3-aroylaziridines with diphenylcyclopropenones and their 1,3-dipolar cycloaddition reactions with diphenylcyclopropenone, N-phenylmaleimide, dimethyl fumarate, and dimethyl maleate were described.

Summary The title compound which incorporates a strained bridgehead double bond and highly deformed cis and trans stilbene structures in bicyclo[4.2.2]-decane ring system was synthesized in good yield as an air-sensitive substance. Some reactions pertinent to strain were examined.