Search

Your search keyword '"Mahdieh Hoseinpour"' showing total 1 results
Start Over Author "Mahdieh Hoseinpour" Journal tetrahedron
1 results on '"Mahdieh Hoseinpour"'

1. A novel and efficient solvent-free and heterogeneous method for the synthesis of primary, secondary and bis-N-acylsulfonamides using metal hydrogen sulfate catalysts

Author

Hamid Javaherian Naghash, Azadeh Molseghi, Mahdieh Hoseinpour, Beheshteh Asadi, Roozbeh Javad Kalbasi, and Ahmad Reza Massah

Subjects
chemistry.chemical_classification, Carboxylic acid, Organic Chemistry, Heterogeneous catalysis, Biochemistry, Chemical synthesis, Catalysis, Sulfonamide, Acylation, chemistry.chemical_compound, Acyl chloride, chemistry, Drug Discovery, Organic chemistry, Imide
Abstract

Some metal hydrogen sulfates were used as acid catalysts in the N-acylation of different sulfonamides using carboxylic acid chlorides and anhydrides as acylating agents under both heterogeneous and solvent-free conditions. Al(HSO 4 ) 3 and Zr(HSO 4 ) 4 were found to have the highest activity and catalyze the reactions efficiently to furnish the primary N -acyl sulfonamides (RCONHSO 2 R′), secondary N -acylsulfonamides (RCONR″SO 2 R′) and bis- N -acylsulfonamnides [RCO(SO 2 R′)N-R″-N(SO 2 R′)COR] in good to high yield. The mild reaction conditions, inexpensive and low toxicity of catalysts and easy work-up procedure make this method attractive.

Published
2009
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results