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Your search keyword '"Weber, Tilmann"' showing total 10 results
Start Over Author "Weber, Tilmann" Journal synthetic and systems biotechnology
10 results on '"Weber, Tilmann"'

2. Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast

Author

Jakočiūnas, Tadas, Klitgaard, Andreas K, Kontou, Eftychia Eva, Nielsen, Julie Bang, Thomsen, Emil, Romero-Suarez, David, Blin, Kai, Petzold, Christopher J, Gin, Jennifer W, Tong, Yaojun, Gotfredsen, Charlotte Held, Charusanti, Pep, Frandsen, Rasmus JN, Weber, Tilmann, Lee, Sang Yup, Jensen, Michael K, and Keasling, Jay D

Subjects
Biological Sciences, Industrial Biotechnology, Bioengineering, Infection, Generic health relevance, Natural products, Synthetic biology, Aromatic polyketides, CRISPR/Cas9, Polyketide, Production platform in eukaryotes, Metabolic engineering, Biotechnology, Biochemistry and cell biology, Bioinformatics and computational biology
Abstract

To accelerate the shift to bio-based production and overcome complicated functional implementation of natural and artificial biosynthetic pathways to industry relevant organisms, development of new, versatile, bio-based production platforms is required. Here we present a novel yeast-based platform for biosynthesis of bacterial aromatic polyketides. The platform is based on a synthetic polyketide synthase system enabling a first demonstration of bacterial aromatic polyketide biosynthesis in a eukaryotic host.

Published
2020

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