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Propargylic amines are versatile synthetic intermediates in organic synthesis and can be readily accessed through a catalytic three-component coupling of aldehydes, alkynes, and amines, termed the "A SP 3 sp coupling". [33] Moreover, reactions of propargylic amine substrates B 1n b and B 1o b bearing alternative amine moieties also proceeded smoothly (Scheme 3). Keywords: 2-boryl allylboronates; propargylic amines; platinum catalysis; bimetallic synergistic effect; diborylation EN 2-boryl allylboronates propargylic amines platinum catalysis bimetallic synergistic effect diborylation 1573 1576 4 07/31/23 20230815 NES 230815 Graph Organoboron compounds play essential roles in organic synthesis and in the pharmaceutical industry. [Extracted from the article]

The cyclopropanation of alkenes through the transition-metal-catalyzed decomposition of diazo compounds is a powerful and straightforward strategy to produce cyclopropanes. Nevertheless, the appeal of further application of this strategy is tempered by the potentially explosive nature of the diazo substrates. Therefore, it is highly desirable to develop sustainable and operationally safe surrogates for diazo compounds. In this Synpacts article, we discuss recent advances on the cyclopropane syntheses through the catalytic cyclopropanation of alkenes and metal carbenes generated in situ from nondiazo precursors as well as highlight our recent progress on the unprecedented molybdenum-catalyzed deoxygenative cyclopropanation reaction of 1,2-dicarbonyl or monocarbonyl compounds. [ABSTRACT FROM AUTHOR]