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Unequivocal international guidelines regarding the diagnosis and management of patients with acute appendicitis are lacking. The aim of the consensus meeting 2015 of the EAES was to generate a European guideline based on best available evidence and expert opinions of a panel of EAES members. After a systematic review of the literature by an international group of surgical research fellows, an expert panel with extensive clinical experience in the management of appendicitis discussed statements and recommendations. Statements and recommendations with more than 70 % agreement by the experts were selected for a web survey and the consensus meeting of the EAES in Bucharest in June 2015. EAES members and attendees at the EAES meeting in Bucharest could vote on these statements and recommendations. In the case of more than 70 % agreement, the statement or recommendation was defined as supported by the scientific community. Results from both the web survey and the consensus meeting in Bucharest are presented as percentages. In total, 46 statements and recommendations were selected for the web survey and consensus meeting. More than 232 members and attendees voted on them. In 41 of 46 statements and recommendations, more than 70 % agreement was reached. All 46 statements and recommendations are presented in this paper. They comprise topics regarding the diagnostic work-up, treatment indications, procedural aspects and post-operative care. The consensus meeting produced 46 statements and recommendations on the diagnostic work-up and management of appendicitis. The majority of the EAES members supported these statements. These consensus proceedings provide additional guidance to surgeons and surgical residents providing care to patients with appendicitis., Competing Interests: Compliance with ethical standards Disclosures Dr. Antoniou received personal fees from the EAES (including Journal and Publication Committee) and from the European Hernia Society. Dr. Muysoms received grants personal fees and non-financial support from Medtronic and Johnson & Johnson. He received grants and personal fees from B. Braun and Dynamesh. He received personal fees from BARD davol, Cousin Biotech, WL Gore@ass and Dansac outside the submitted work. Prof. Dr. Bonjer received grants and personal fees from Johnson & Johnson, Applied Medical, Medtronic and Olympus. He received personal fees from Cook. All outside the submitted work. Drs. Defoort, Dr. Go, Prof. Dr. Ozmen, Dr. Rhodes, Drs. Gorter, Dr. Eker, Drs Gorter-Stam, Drs. Abis, Drs. Acharya, Drs. Ankersmit, Drs. Arolfo, Drs. Babic, Prof. Dr. Boni, Drs. Bruntink, Drs. Van Dam, Drs. Deijen, Drs. DeLacy, Drs. Harmsen, Drs. Van den Helder, Dr. Iordache, Drs. Ket, Drs. Papoulas, Drs. Straatman, Drs. Tenhagen, Drs. Turrado, Dr. Vereczkei, Prof. Dr. Vilallonga and Drs. Deelder have no conflict of interest or financial ties to disclose.