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8 results on '"Britta Will"'

1. New Trogocytosis Study Findings Recently Were Reported by Researchers at Albert Einstein College of Medicine (Regulation of the Hematopoietic Stem Cell Pool By C-kit-associated Trogocytosis).

Subjects
CONNECTIVE tissue cells, BONE marrow cells, MYELOID cells, HEMATOPOIETIC stem cells, RETICULO-endothelial system
Abstract

Researchers at Albert Einstein College of Medicine in Bronx, New York have conducted a study on trogocytosis, a process by which cells acquire molecules from other cells. The study focused on hematopoietic stem cells (HSCs), which are routinely mobilized from the bone marrow for transplantation. The researchers found that a subset of HSCs displayed macrophage-associated markers on their cell surface, suggesting that these HSCs were selectively retained in the bone marrow. The study provides evidence that adult stem cells use trogocytosis to establish and activate molecular mechanisms. [Extracted from the article]

Published
2024

2. Study Results from Albert Einstein College of Medicine Update Understanding of Hematopoietic Stem Cells (An Iron Rheostat Controls Hematopoietic Stem Cell Fate).

Subjects
HEMATOPOIETIC stem cells, MULTIPOTENT stem cells, IRON, STEM cell research, BONE marrow cells
Abstract

A recent study conducted by researchers at the Albert Einstein College of Medicine in New York City has shed light on the mechanisms that control the fate of hematopoietic stem cells (HSPCs), which are responsible for blood production. The study found that transitory free cytoplasmic iron plays a role in regulating the fate of adult stem cells. The researchers discovered that limited iron availability triggers metabolic and epigenetic events that regulate stemness-conferring gene expression. Additionally, the study found that aging-related iron loading can impair cell fate control in aged stem cells. This research provides insights into potential intervention strategies for dysfunctional aged stem cells. [Extracted from the article]

Published
2024

3. Research from Albert Einstein College of Medicine in the Area of Acute Myeloid Leukemia Published (TMIGD2 is an orchestrator and therapeutic target on human acute myeloid leukemia stem cells).

Subjects
ACUTE myeloid leukemia, STEM cells, MYELOID leukemia, THERAPEUTICS, STEM cell research
Abstract

A recent study conducted by researchers at Albert Einstein College of Medicine has identified a potential therapeutic target for acute myeloid leukemia (AML). The study found that a protein called TMIGD2 is expressed by AML cells and plays a crucial role in the development and maintenance of the disease. Targeting TMIGD2 with monoclonal antibodies was shown to reduce leukemia burden in AML patient-derived xenograft models without affecting normal hematopoietic stem/progenitor cells. These findings provide a promising strategy for the treatment of AML. [Extracted from the article]

Published
2024

4. New Trogocytosis Study Findings Recently Were Reported by Researchers at Albert Einstein College of Medicine (Regulation of the Hematopoietic Stem Cell Pool By C-kit-associated Trogocytosis)

Subjects
United States. National Institutes of Health -- Reports, Bone marrow -- Transplantation, Hematopoietic stem cells -- Reports -- Research, Health, Yeshiva University. Albert Einstein College of Medicine -- Reports
Abstract

2024 SEP 9 (NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Week -- Fresh data on Trogocytosis are presented in a new report. According to news reporting [...]

Published
2024

5. Study Results from Albert Einstein College of Medicine Update Understanding of Hematopoietic Stem Cells (An Iron Rheostat Controls Hematopoietic Stem Cell Fate)

Subjects
Cell Press, Hematopoietic stem cells -- Research, Periodical publishing -- Research, Stem cell research -- Research, Health
Abstract

2024 JUN 3 (NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Week -- Current study results on Stem Cell Research - Hematopoietic Stem Cells have been published. [...]

Published
2024

6. Research from Albert Einstein College of Medicine in the Area of Acute Myeloid Leukemia Published (TMIGD2 is an orchestrator and therapeutic target on human acute myeloid leukemia stem cells)

Subjects
Oncology, Experimental -- Reports, Social service -- Reports -- Research, Stem cells -- Reports -- Research, Medical colleges -- Research -- Reports, Cancer -- Research, Stem cell research -- Research -- Reports, Health, Yeshiva University. Albert Einstein College of Medicine -- Reports
Abstract

2024 JAN 22 (NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Week -- New study results on acute myeloid leukemia have been published. According to news reporting [...]

Published
2024

7. Researchers from Albert Einstein College of Medicine Describe Research in Acute Myeloid Leukemia (Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations)

Subjects
Oncology, Experimental -- Genetic aspects, Stem cells -- Genetic aspects -- Research, Cancer -- Research, Health, Yeshiva University. Albert Einstein College of Medicine
Abstract

2022 SEP 12 (NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Week -- Current study results on acute myeloid leukemia have been published. According to news reporting [...]

Published
2022

8. Studies from Albert Einstein College of Medicine in the Area of Science Reported (Chaperone-mediated Autophagy Sustains Haematopoietic Stem-cell Function)

Subjects
United States. National Institutes of Health, Medical colleges -- Research, Hematopoietic stem cells -- Research, Stem cell research -- Research, Health, Yeshiva University. Albert Einstein College of Medicine
Abstract

2021 FEB 15 (NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Week -- Investigators discuss new findings in Science. According to news reporting originating from New York [...]

Published
2021

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